Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2013	TCMT223	Aldose reductase	Homo sapiens	IC50: 2700 (nM), Ref: 22261024
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC949	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 19911821
TCMC949	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 48 (nM), Ref: 19911821
TCMC949	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9100 (nM), Ref: 19911821
TCMC949	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3300 (nM), Ref: 19911821
TCMC949	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 2000 (nM), Ref: 19911821
TCMC949	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 5200 (nM), Ref: 19911821
TCMC949	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9400 (nM), Ref: 19911821
TCMC949	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6800 (nM), Ref: 19911821
TCMC949	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 5600 (nM), Ref: 19911821
TCMC949	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270
TCMC949	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1113	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC1774	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 20674354 Ki: 3100 (nM), Ref: 21282059 Ki: 3400 (nM), Ref: 22137345
TCMC1774	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9300 (nM), Ref: 22137345
TCMC785	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 610 (nM), Ref: 23062825
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1828	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 900 (nM), Ref: 17994701
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1425	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 71 (ug/ml), Ref: 1710653 IC50: 71 (ug/ml), Ref: 21295891
TCMC785	TCMT1104	Sortase	Staphylococcus aureus	IC50: 8.7 (ug/ml), Ref: 17716892 IC50: 8.7 (ug/ml), Ref: 19269184
TCMC785	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 100 (ug/ml), Ref: 1710653 IC50: 100 (ug/ml), Ref: 21295891
TCMC785	TCMT1154	Sortase	Staphylococcus aureus	IC50: 40.6 (ug/ml), Ref: 26551342
TCMC1491	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 0.00423 (ug/ml), Ref: 21334901 IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2013	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2398	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.557 (ug/ml), Ref: 3286870 IC50: 2.008 (ug/ml), Ref: 3286870
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC1113	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 15863332
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1425	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.422 (ug/ml), Ref: 3286870 IC50: 1.607 (ug/ml), Ref: 3286870
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC785	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.36 (ug/ml), Ref: 10.1016/S0960-894X(00)80357-1 IC50: 0.141 (ug/ml), Ref: 3286870 IC50: 0.148 (ug/ml), Ref: 3286870
TCMC785	TCMT1246	Escherichia coli	Escherichia coli	MIC: 5 (ug/ml), Ref: 16359864 MIC: 31.25 (ug/ml), Ref: 18591276
TCMC785	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 16730982 MIC: 31.3 (ug/ml), Ref: 16872133
TCMC785	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 17716892 MIC: 50 (ug/ml), Ref: 9784149 MIC: 60 (ug/ml), Ref: 15568768 MBC: 64 (ug/ml), Ref: 10.1007/s00044-013-0844-5 MIC: 32 (ug/ml), Ref: 10.1007/s00044-013-0844-5
TCMC785	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 100 (ug/ml), Ref: 9784149
TCMC785	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 25 (ug/ml), Ref: 9784149
TCMC785	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 9784149 MIC: 31.3 (ug/ml), Ref: 16872133 MIC: 15.6 (ug/ml), Ref: 16872133
TCMC785	TCMT1385	Candida shehatae	Candida shehatae	MIC: 7.8 (ug/ml), Ref: 16872133
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1491	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491	TCMT1318	Human T-lymphotropic virus 1	Human T-lymphotropic virus 1	IC50: 1.07 (ug/ml), Ref: 21334901
TCMC1828	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.281 (ug/ml), Ref: 3286870 IC50: 0.163 (ug/ml), Ref: 3286870
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2811	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.35 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1113	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 16 (nM), Ref: 17263522
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242