TCM Putative Target References: TCMFx1161


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1173
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9430 (nM), Ref: 20185318
Ki: 9430 (nM), Ref: 26498394
TCMC1173
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9780 (nM), Ref: 20185318
Ki: 9780 (nM), Ref: 26498394
TCMC1173
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9870 (nM), Ref: 20185318
TCMC1173
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7410 (nM), Ref: 20185318
TCMC1173
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 8450 (nM), Ref: 20185318
TCMC1173
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7040 (nM), Ref: 20185318
TCMC1173
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2400 (nM), Ref: 20185318
TCMC1173
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2890 (nM), Ref: 20185318
TCMC338
TCMT318 Putative hexokinase HKDC1 Homo sapiens IC50: 2490 (nM), Ref: IC50: 3540 (nM), Ref:
TCMC2119
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9140 (nM), Ref: 20185318
TCMC2119
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9010 (nM), Ref: 20185318
TCMC2119
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 8200 (nM), Ref: 20185318
TCMC2119
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7810 (nM), Ref: 20185318
TCMC2119
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7550 (nM), Ref: 20185318
TCMC2119
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6340 (nM), Ref: 20185318
TCMC2119
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 8580 (nM), Ref: 20185318
TCMC2119
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 3190 (nM), Ref: 20185318
TCMC2119
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 4150 (nM), Ref: 20185318
TCMC1582
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 4100 (nM), Ref: 22668600
TCMC1582
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 820 (nM), Ref: 22668600
TCMC1582
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 5500 (nM), Ref: 22668600
TCMC1582
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 780 (nM), Ref: 22668600
TCMC1582
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 3400 (nM), Ref: 22668600
TCMC1582
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2600 (nM), Ref: 22668600
TCMC1748
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 85 (nM), Ref: 16562853
Ki: 314 (nM), Ref: 25695425
TCMC1748
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 373 (nM), Ref: 25695425
TCMC1748
TCMT160 Serotonin 7 (5-HT7) receptor Homo sapiens Ki: 20 (nM), Ref: 25695425
TCMC1748
TCMT315 Serotonin 6 (5-HT6) receptor Homo sapiens Ki: 306 (nM), Ref: 25695425
TCMC1748
TCMT646 Serotonin 5a (5-HT5a) receptor Homo sapiens Ki: 566 (nM), Ref: 25695425
TCMC1748
TCMT313 Serotonin 2b (5-HT2b) receptor Homo sapiens Ki: 323 (nM), Ref: 25695425
TCMC1741
TCMT161 Hydroxycarboxylic acid receptor 2 Homo sapiens IC50: 140 (nM), Ref: 17994679
IC50: 140 (nM), Ref: 18029181
Ki: 50 (nM), Ref: 18665582
IC50: 150 (nM), Ref: 18752940
IC50: 140 (nM), Ref: 19307116
IC50: 130 (nM), Ref: 18760600
IC50: 140 (nM), Ref: 19309152
IC50: 140 (nM), Ref: 19592242
IC50: 140 (nM), Ref: 19592242
Ki: 82 (nM), Ref: 20184326
Ki: 104 (nM), Ref: 20184326
IC50: 140 (nM), Ref: 20444602
IC50: 140 (nM), Ref: 20615702
IC50: 249 (nM), Ref: 25737085
TCMC6
TCMT46 Coagulation factor III Homo sapiens IC50: 152.43 (nM), Ref: 23199480
TCMC6
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 50 (nM), Ref: 23332346
TCMC6
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 305 (nM), Ref: 23332346
TCMC6
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 149 (nM), Ref: 23332346
TCMC1556
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3840 (nM), Ref: 21402476
TCMC1556
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 3530 (nM), Ref: 21402476
TCMC2111
TCMT614 Egl nine homolog 1 Homo sapiens IC50: 3000 (nM), Ref: 18942826
TCMC1839
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 9800 (nM), Ref: 18501600
Ki: 9800 (nM), Ref: 18579385
Ki: 920 (nM), Ref: 20185318
TCMC1839
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4800 (nM), Ref: 18579385
Ki: 6270 (nM), Ref: 20185318
TCMC1839
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 9200 (nM), Ref: 18579385
Ki: 3670 (nM), Ref: 20185318
TCMC1839
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 6160 (nM), Ref: 20185318
TCMC1839
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 3730 (nM), Ref: 20185318
TCMC1839
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1839
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 5700 (nM), Ref: 20185318
TCMC1839
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 7130 (nM), Ref: 20185318
TCMC1839
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1839
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 6610 (nM), Ref: 20185318
TCMC1839
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 870 (nM), Ref: 20185318
TCMC1566
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 830 (nM), Ref: 22668600
TCMC1566
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 810 (nM), Ref: 22668600
TCMC1566
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 850 (nM), Ref: 22668600
TCMC1566
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 820 (nM), Ref: 22668600
TCMC1566
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 800 (nM), Ref: 22668600
TCMC1566
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 780 (nM), Ref: 22668600
TCMC848
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 7.28 (nM), Ref: 23375794
TCMC848
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 8.2 (nM), Ref: 23375794
TCMC848
TCMT295 Matrix metalloproteinase-1 Homo sapiens IC50: 3301.33 (nM), Ref: 23375794
TCMC2209
TCMT597 Solute carrier family 28 member 3 Homo sapiens Ki: 3400 (nM), Ref: 23388705
IC50: 5400 (nM), Ref: 23388705
TCMC2209
TCMT710 Sodium/nucleoside cotransporter 1 Homo sapiens Ki: 5200 (nM), Ref: 23388705
IC50: 5800 (nM), Ref: 23388705

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC995
TCMT1104 Sortase Staphylococcus aureus IC50: 18.3 (ug/ml), Ref: 16154746
TCMC2317
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 3.9 (ug/ml), Ref: 8786363
IC50: 2.53 (ug/ml), Ref: 8786363
TCMC2317
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 3.9 (ug/ml), Ref: 8786363
IC50: 2.53 (ug/ml), Ref: 8786363
TCMC553
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2107
TCMT1294 Human parainfluenza virus 3 Human parainfluenza virus 3 IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 20542692
TCMC1582
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582
TCMT1232 Pseudomonas aeruginosa Pseudomonas aeruginosa MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582
TCMT1246 Escherichia coli Escherichia coli MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 12.5 (ug/ml), Ref: 18539361
TCMC1582
TCMT1170 Enterobacter cloacae Enterobacter cloacae MIC: 25 (ug/ml), Ref: 18539361
TCMC1748
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 7.15 (ug/ml), Ref: 8786363
IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 7.15 (ug/ml), Ref: 8786363
IC50: 2.7 (ug/ml), Ref: 8786363
TCMC2458
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 50 (ug/ml), Ref: 20542692
TCMC2459
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 37.5 (ug/ml), Ref: 9748372
TCMC2506
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 1.99 (ug/ml), Ref: 8786363
IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 1.99 (ug/ml), Ref: 8786363
IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1387
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 1.9 (ug/ml), Ref: 8786363
IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 1.9 (ug/ml), Ref: 8786363
IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2528
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 50 (ug/ml), Ref: 20476748
TCMC2543
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 1.6 (ug/ml), Ref: 20384293
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC2566
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC801
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 32 (ug/ml), Ref: 15844943
TCMC801
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2642
TCMT1251 Candida albicans Candida albicans IC50: 3.5 (ug/ml), Ref: 12088427
MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans MIC: 12.5 (ug/ml), Ref: 12088427
IC50: 2 (ug/ml), Ref: 12088427
TCMC2642
TCMT1218 Staphylococcus aureus Staphylococcus aureus IC50: 2 (ug/ml), Ref: 12088427
MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642
TCMT1355 Rhodococcus equi Rhodococcus equi MIC: 10 (ug/ml), Ref: 19639965
TCMC2642
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 12 (ug/ml), Ref: 19874044
TCMC2642
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 50 (ug/ml), Ref: 20476748
TCMC2642
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 12.5 (ug/ml), Ref: 22280816