Organism Name: A new engineered strain of Escherichia coli [MetJ]

Organism ID:   NPO41935
Organism Name:   A new engineered strain of Escherichia coli [MetJ]
Native / Engineered Organism:   Engineered Organism
Matched Taxonomy Level:   Strain
Organism External ID:   NCBI_Taxonomy_ID[ n.a.]
Organism Synonyms:  
Genus:   Escherichia
Family:   Enterobacteriaceae
Kingdom:   n.a.
SuperKingdom:   Bacteria

  Individual Natural Products

Natural Product ID Prefer Name (or InChiKey) IUPAC Name Number of Targets Number of Activity Records
NPC50898 Apigenin 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one 399 1052

  NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)

Organism Name Producer Organism Inducer Organism NP ID NP Name Effect of Co-culture Reference

  NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)

Organism Name Parent Organism Name Engineered Gene in Organism Purpose of Engineering Engineering Category Engineering Description NP ID NP Name NP Yeild of Parent Organism NP Yeild of Engineered Organism Yeild Change Reference
A new engineered strain of Escherichia coli Escherichia coli MetJ Increase NP yield n.a. modulation of plasmid copy number and optimization of VvAOMT1 and CkmOMT2 expression conditions; CRISPRi was utilized to silence the transcriptional repressor MetJ NPC50898 Apigenin n.a. 51 mg/L (56 mg/L upon scale-up to shake flask) 21-fold improvement overall PMID[28095853]

  The Quantitative Compositions of NPs in Organism

Organism ID NP ID Organism Material Preparation Organism Part NP Quantity (Standard) NP Quantity (Minimum) NP Quantity (Maximum) Quantity Unit Reference