Organism ID:   | NPO41935 |
Organism Name:   | A new engineered strain of Escherichia coli [MetJ] |
Native / Engineered Organism:   | Engineered Organism |
Matched Taxonomy Level:   | Strain |
Organism External ID:   | NCBI_Taxonomy_ID[ n.a.] |
Organism Synonyms:   | |
Genus:   | Escherichia |
Family:   | Enterobacteriaceae |
Kingdom:   | n.a. |
SuperKingdom:   | Bacteria |
Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
---|---|---|---|---|
NPC50898 | Apigenin | 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | 399 | 1052 |
Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|
A new engineered strain of Escherichia coli | Escherichia coli | MetJ | Increase NP yield | n.a. | modulation of plasmid copy number and optimization of VvAOMT1 and CkmOMT2 expression conditions; CRISPRi was utilized to silence the transcriptional repressor MetJ | NPC50898 | Apigenin | n.a. | 51 mg/L (56 mg/L upon scale-up to shake flask) | 21-fold improvement overall |
PMID[28095853] |
Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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