Organism Name: A new engineered strain of Yarrowia lipolytica [n.a.]| Organism ID: | NPO41916 |
| Organism Name: | A new engineered strain of Yarrowia lipolytica [n.a.] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Yarrowia |
| Family: | Dipodascaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC99088 | Lycopene | (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene | 14 | 43 |
| NPC123965 | Squalene | (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene | 9 | 17 |
| NPC98386 | Soyasapogenol B | (3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-3,9-diol | 8 | 19 |
| NPC236709 | Succinic Acid | butanedioic acid | 18 | 45 |
| NPC88839 | Isobutanol | 2-methylpropan-1-ol | 9 | 25 |
| NPC79943 | 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydrochromen-4-One | 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one | 35 | 59 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Increase NP yield | Microbial chassis engineering | Culture condition optimization of Y. lipolytica via nutrient screening and coexpression of a myxo-ppt with the artificial PUFA gene cluster from myxobacteria | NPC88839 | isobutanol | n.a. | 0.168 | n.a. |
PMID[31492836] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Novel NPs activation | n.a. | n.a. | NPC99088 | lycopene | n.a. | 1.5 g/L; 0.048 g/g | n.a. |
PMID[28986998] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | NP biosynthesis | n.a. | n.a. | NPC79943 | Naringenin | n.a. | 134.2 mg/L | n.a. |
PMID[31622552] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Increase NP yield | n.a. | n.a. | NPC98386 | soyasapogenol B | n.a. | 48.1 mg/L | n.a. |
PMID[30695641] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Novel NPs activation | n.a. | n.a. | NPC123965 | Squalene | n.a. | 6.5 g/L; 90 mg/g DCW | n.a. |
PMID[28986998] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Increase NP yield | n.a. | n.a. | NPC123965 | Squalene | n.a. | 54.2 mg/L | n.a. |
PMID[30695641] |
| A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | n.a. | Increase NP yield | n.a. | n.a. | NPC236709 | Succinic Acid | n.a. | 71.2 mg/L | n.a. |
PMID[30695641] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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