Organism ID:   | NPO41915 |
Organism Name:   | A new engineered strain of Yarrowia lipolytica [CLA4 MHY1] |
Native / Engineered Organism:   | Engineered Organism |
Matched Taxonomy Level:   | Strain |
Organism External ID:   | NCBI_Taxonomy_ID[ n.a.] |
Organism Synonyms:   | |
Genus:   | Yarrowia |
Family:   | Dipodascaceae |
Kingdom:   | Fungi |
SuperKingdom:   | Eukaryota |
Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
---|---|---|---|---|
NPC123965 | Squalene | (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene | 9 | 17 |
Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|
A new engineered strain of Yarrowia lipolytica | Yarrowia lipolytica | CLA4 MHY1 | Increase NP yield | Microbial chassis engineering | the strains were morphologically engineered by deleting CLA4 and MHY1 genes to convert the mycelium back to the yeast form, which further increased the β-carotene production by 139%. | NPC123965 | squalene | n.a. | 7.6 g/L and 159 mg/g DCW | n.a. |
PMID[34762415] |
Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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