Organism Name: A new engineered strain of Saccharomyces cerevisiae JDY52 [GgbAS, MtCPR, CYP716A12, AtCPR, LjCPR]| Organism ID: | NPO41899 |
| Organism Name: | A new engineered strain of Saccharomyces cerevisiae JDY52 [GgbAS, MtCPR, CYP716A12, AtCPR, LjCPR] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Saccharomyces |
| Family: | Saccharomycetaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC313627 | DGGZCXUXASNDAC-QQNGCVSVSA-N | n.a. | 2 | 6 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Saccharomyces cerevisiae JDY52 | Saccharomyces cerevisiae JDY52 | GgbAS, MtCPR, CYP716A12, AtCPR, LjCPR | Increase NP yield | n.a. | 1) improving the pairing efficiency between cytochrome P450 monooxygenase and reductase; 2) the cellular galactose regulatory network was reconstructed by knocking out galactose metabolic genes GAL80 and GAL1; 3) the 3-hydroxy-3-methylglutaryl-CoA reductase, squalene synthase and 2,3-oxidosqualene synthase were further overexpressed | NPC313627 | C-1027 | n.a. | 606.9 ± 9.1 mg/L | 7.6-fold |
PMID[29526355] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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