Organism Name: A new engineered strain of Saccharomyces cerevisiae BY4724 [PgDDS, PgPPDS, AtCPR1]| Organism ID: | NPO41888 |
| Organism Name: | A new engineered strain of Saccharomyces cerevisiae BY4724 [PgDDS, PgPPDS, AtCPR1] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Saccharomyces |
| Family: | Saccharomycetaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC202771 | Noscapine | (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one | 114 | 395 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Saccharomyces cerevisiae BY4724 | Saccharomyces cerevisiae BY4724 | PgDDS, PgPPDS, AtCPR1 | Increase NP yield | n.a. | 1) dammarenediol-II synthase and protopanaxadiol synthase genes of Panax ginseng, together with a NADPH-cytochrome P450 reductase gene of Arabidopsis thaliana, were introduced into Saccharomyces cerevisiae; 2) overexpressing truncated 3-hydroxyl-3-methylglutaryl-CoA reductase, farnesyl diphosphate synthase, squalene synthase and 2,3-oxidosqualene synthase genes, together with increasing protopanaxadiol synthase activity through codon optimization | NPC202771 | noscapine | n.a. | 1548 mg/L | n.a. |
PMID[24126082] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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