Organism Name: A new engineered strain of Escherichia coli [AcrAB-TolC, MdtEF-TolC, mexAB-OprM]| Organism ID: | NPO41859 |
| Organism Name: | A new engineered strain of Escherichia coli [AcrAB-TolC, MdtEF-TolC, mexAB-OprM] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Escherichia |
| Family: | Enterobacteriaceae |
| Kingdom: | n.a. |
| SuperKingdom: | Bacteria |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC490991 | Valencene | (3R,4aS,5R)-4a,5-dimethyl-3-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene | 0 | 0 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Escherichia coli | Escherichia coli | AcrAB-TolC, MdtEF-TolC, mexAB-OprM | Heterologous biosynthesis; Increase NP yield | Transporter engineering | Overexpression of native efflux pumps AcrAB-TolC, MdtEF-TolC; Overexpression of exogenous pumps mexAB-OprM; and Modulating the copy number of pump | NPC490991 | sesquiterpene (+)-valencene | n.a. | 404 mg/L | n.a. |
PMID[23864262] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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