Organism Name: A new engineered strain of Corynebacterium glutamicum [n.a.]| Organism ID: | NPO41838 |
| Organism Name: | A new engineered strain of Corynebacterium glutamicum [n.a.] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Corynebacterium |
| Family: | Corynebacteriaceae |
| Kingdom: | n.a. |
| SuperKingdom: | Bacteria |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC316205 | Tylosin | 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde | 45 | 158 |
| NPC94167 | Riboflavin | 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione | 45 | 211 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Corynebacterium glutamicum | Corynebacterium glutamicum | n.a. | Construct NP producting platform strain | n.a. | four gene clusters comprising 21 genes involved in the catabolism of aromatic compounds were deleted; Expression of plant-derived and codon-optimized genes coding for a chalcone synthase (CHS) and a chalcone isomerase (CHI) | NPC94167 | riboflavin | n.a. | 35 mg/L | n.a. |
PMID[27288926] |
| A new engineered strain of Corynebacterium glutamicum | Corynebacterium glutamicum | n.a. | Increase NP yield | n.a. | n.a. | NPC316205 | Tylosin | n.a. | titer: 120 g/L; yield: 0.55 g lysine/g glucose | n.a. |
PMID[21241816] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
|---|