Organism Name: A new engineered strain of Aspergillus spp. [n.a.]| Organism ID: | NPO41833 |
| Organism Name: | A new engineered strain of Aspergillus spp. [n.a.] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Aspergillus |
| Family: | Aspergillaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC236637 | Homoeriodictyol | (2S)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one | 13 | 30 |
| NPC115906 | Hydrocodone | (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one | 13 | 32 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A new engineered strain of Aspergillus spp. | Aspergillus spp. | n.a. | Increase NP yield | Microbial chassis engineering | Genome reduction of A. nidulans via deleting 6 endogenous BGCs to eliminate undesired toxins and substrates competition, combined with establishment of an efficient heterologous expression procedure | NPC236637 | Homoeriodictyol | n.a. | n.a. | Titer increase |
PMID[23621425] |
| A new engineered strain of Aspergillus spp. | Aspergillus spp. | n.a. | Increase NP yield | Microbial chassis engineering | Establishment of precursors biosynthesis and metabolic engineering of A. oryzae for heterologous production of polyketides | NPC115906 | hydrocodone | n.a. | n.a. | Titer increase |
PMID[34947068] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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