Organism Name: Yarrowia lipolytica ST6075 [crtW crtZ]| Organism ID: | NPO41826 |
| Organism Name: | Yarrowia lipolytica ST6075 [crtW crtZ] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Yarrowia |
| Family: | Dipodascaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC84319 | Maslinic Acid | (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | 53 | 170 |
| NPC94167 | Riboflavin | 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione | 45 | 211 |
| NPC123965 | Squalene | (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene | 9 | 17 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Yarrowia lipolytica ST6075 | Yarrowia lipolytica 5999 | crtW crtZ | Increase NP yield | n.a. | introduced b-carotene ketolase (crtW) from Paracoccus sp. N81106 and hydroxylase (crtZ) from Pantoea ananatis to convert b-carotene into astaxanthin; XdcrtI↑-XdcrtYB↑, PscrtW↑-PacrtZ↑ & XdcrtI↑-XdcrtYB↑, loop-out hphMX (parent strain: ST5204) | NPC84319 | Maslinic acid | n.a. | 10.4 ± 0.5 mg/L | n.a. |
PMID[29552653] |
| Yarrowia lipolytica ST6075 | Yarrowia lipolytica 5999 | crtW crtZ | Increase NP yield | n.a. | introduced b-carotene ketolase (crtW) from Paracoccus sp. N81106 and hydroxylase (crtZ) from Pantoea ananatis to convert b-carotene into astaxanthin; XdcrtI↑-XdcrtYB↑, PscrtW↑-PacrtZ↑ & XdcrtI↑-XdcrtYB↑, loop-out hphMX (parent strain: ST5204) | NPC94167 | riboflavin | n.a. | 35.3 ± 1.8 mg/L | n.a. |
PMID[29552653] |
| Yarrowia lipolytica ST6075 | Yarrowia lipolytica 5999 | crtW crtZ | Increase NP yield | n.a. | introduced b-carotene ketolase (crtW) from Paracoccus sp. N81106 and hydroxylase (crtZ) from Pantoea ananatis to convert b-carotene into astaxanthin; XdcrtI↑-XdcrtYB↑, PscrtW↑-PacrtZ↑ & XdcrtI↑-XdcrtYB↑, loop-out hphMX (parent strain: ST5204) | NPC123965 | Squalene | n.a. | 5.7 ± 0.5 mg/L | n.a. |
PMID[29552653] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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