Organism ID:   | NPO41816 |
Organism Name:   | Streptomyces spp. [n.a.] |
Native / Engineered Organism:   | Engineered Organism |
Matched Taxonomy Level:   | Strain |
Organism External ID:   | NCBI_Taxonomy_ID[ n.a.] |
Organism Synonyms:   | |
Genus:   | Streptomyces |
Family:   | Streptomycetaceae |
Kingdom:   | |
SuperKingdom:   | Bacteria |
Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
---|---|---|---|---|
NPC14552 | geosmin | n.a. | 2 | 2 |
NPC120123 | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-Hydroxy-17-[(2S)-2-Hydroxy-6-Methylhept-5-En-2-Yl]-4,4,8,10,14-Pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-Yl]Oxy]-6-(Hydroxymethyl)Oxan-3-Yl]Oxy-6-(Hydroxymethyl)Oxane-3,4,5-Triol | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | 16 | 45 |
NPC47566 | Ginsenoside Rh1 | (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 5 | 15 |
NPC88000 | Ginsenoside Rh2 | (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 72 | 86 |
NPC160734 | Ginsenoside F1 | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol | 4 | 5 |
NPC490501 | glidobactin a | n.a. | 0 | 0 |
NPC490829 | Glidopeptin A | n.a. | 0 | 0 |
Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|
Streptomyces spp. | Streptomyces spp. | n.a. | Novel NPs activation | Microbial chassis engineering | Genome reduction of S. albus by deleting 15 dispensable endogenous BGCs and increase copy number of exogenous BGCs via introducing phiC31 attB sites to generate cluster-free strains | NPC14552 | geosmin | n.a. | n.a. | n.a. |
PMID[30196100] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Genome reduction of S. albus by deleting 15 dispensable endogenous BGCs and increase copy number of exogenous BGCs via introducing phiC31 attB sites to generate cluster-free strains | NPC120123 | Ginsenoside Rg3 | n.a. | n.a. | Titer increase |
PMID[30196100] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Genome reduction of S. albus by deleting 15 dispensable endogenous BGCs and increase copy number of exogenous BGCs via introducing phiC31 attB sites to generate cluster-free strains | NPC47566 | Ginsenoside Rh1 | n.a. | n.a. | Titer increase |
PMID[30196100] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Genome reduction of S. albus by deleting 15 dispensable endogenous BGCs and increase copy number of exogenous BGCs via introducing phiC31 attB sites to generate cluster-free strains | NPC88000 | Ginsenoside Rh2 | n.a. | n.a. | Titer increase |
PMID[30196100] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Genome reduction of S. albus by deleting 15 dispensable endogenous BGCs and increase copy number of exogenous BGCs via introducing phiC31 attB sites to generate cluster-free strains | NPC160734 | Ginsenoside F1 | n.a. | n.a. | Titer increase |
PMID[30196100] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Metabolic and morphological engineering of Streptomyces hosts via adding microparticles to submerged cultures | NPC490501 | glidobactin A | n.a. | n.a. | Titer increase |
PMID[32808679] |
Streptomyces spp. | Streptomyces spp. | n.a. | Increase NP yield | Microbial chassis engineering | Metabolic and morphological engineering of Streptomyces hosts via adding microparticles to submerged cultures | NPC490829 | glidopeptin A | n.a. | n.a. | Titer increase |
PMID[33974270] |
Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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