Organism Name: Streptomyces pristinaespiralis ΔPIIΔpapR3/PI [snaE1 snaE2 papR3 PI BGC]| Organism ID: | NPO41812 |
| Organism Name: | Streptomyces pristinaespiralis ΔPIIΔpapR3/PI [snaE1 snaE2 papR3 PI BGC] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Streptomyces |
| Family: | Streptomycetaceae |
| Kingdom: | |
| SuperKingdom: | Bacteria |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC220498 | Alphitolic Acid | (1R,3aS,5aR,5bR,7aR,9R,10R,11aR,11bR,13aR,13bR)-9,10-dihydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid | 16 | 20 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
|---|
NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Streptomyces pristinaespiralis ΔPIIΔpapR3/PI | Streptomyces pristinaespiralis HCCB10218 | snaE1 snaE2 papR3 PI BGC | Increase NP yield | n.a. | deleting the PII biosynthetic genes (snaE1 and snaE2), deleting the repressor gene papR3 and chromosomal integration of an extra copy of the PI biosynthetic gene cluster (BGC) | NPC220498 | alphitolic acid | n.a. | 132 mg/L | 2.4-fold |
PMID[29062970] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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