Organism Name: Shimwellia blattae (p424IbPSO, pIZpntAB) [AdhA; pntAB]| Organism ID: | NPO41785 |
| Organism Name: | Shimwellia blattae (p424IbPSO, pIZpntAB) [AdhA; pntAB] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Shimwellia |
| Family: | n.a. |
| Kingdom: | n.a. |
| SuperKingdom: | n.a. |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC490700 | 4ʹ-o-methyl-daidzein | n.a. | 0 | 0 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Shimwellia blattae (p424IbPSO, pIZpntAB) | Shimwellia blattae (p424IbPSO) | AdhA; pntAB | Increase NP yield | n.a. | we have overexpressed the NAD-dependent alcohol dehydrogenase (AdhA) from L. lactis to offer a new enzyme to finish the pathway. Second, we have modulated the cell redox balance of the host by cloning the pntAB transhydrogenase encoding gene from E. coli to increase the NADPH levels required by IlvC and YqhD reductases. | NPC490700 | 4ʹ-O-methyl-daidzein | total yield 11.9% | total yield 16.4%; 5.98 g/L; 0.19 ± 0.010 gIbOH/L h; 2.32 ± 0,12gIbOH g/X | 19.3% higher isobutanol production; 39.0% more isobutanol than the original strain |
PMID[33407735] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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