Organism Name: Saccharomyces cerevisiae: AY-SB1 (ΔBDH1:loxP/ΔBDH1:loxP) and AY-SD1B2 (ΔBDH1:loxP-PGK1p-BDH2-PGK1t/ΔBDH1:loxP-PGK1p-BDH2-PGK1t) [BDH1 BDH2 ALS ILV2]| Organism ID: | NPO41777 |
| Organism Name: | Saccharomyces cerevisiae: AY-SB1 (ΔBDH1:loxP/ΔBDH1:loxP) and AY-SD1B2 (ΔBDH1:loxP-PGK1p-BDH2-PGK1t/ΔBDH1:loxP-PGK1p-BDH2-PGK1t) [BDH1 BDH2 ALS ILV2] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Saccharomyces |
| Family: | Saccharomycetaceae |
| Kingdom: | Fungi |
| SuperKingdom: | Eukaryota |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC490706 | 6-deb | n.a. | 0 | 0 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saccharomyces cerevisiae: AY-SB1 (ΔBDH1:loxP/ΔBDH1:loxP) and AY-SD1B2 (ΔBDH1:loxP-PGK1p-BDH2-PGK1t/ΔBDH1:loxP-PGK1p-BDH2-PGK1t) | Saccharomyces cerevisiae AY15 | BDH1 BDH2 ALS ILV2 | Increase NP yield | Metabolic Engineering | disrupting BDH1, overexpressing BDH2, he α-acetolactate synthase (ALS) and replacing the promoter of the ILV2 gene with a strong promoter (PGK1p) | NPC490706 | 6-dEB | n.a. | AY-SBI: 7.58 mg/L; AY-SD1B2: 9.47 mg/L | 2.3- and 2.87-fold increase |
PMID[33324376] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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