Organism ID:   | NPO41747 |
Organism Name:   | Recombinant Saccharomyces cerevisiae(overexpressed strain MO3) [ACE1] |
Native / Engineered Organism:   | Engineered Organism |
Matched Taxonomy Level:   | Strain |
Organism External ID:   | NCBI_Taxonomy_ID[ n.a.] |
Organism Synonyms:   | |
Genus:   | Recombinant |
Family:   | n.a. |
Kingdom:   | n.a. |
SuperKingdom:   | n.a. |
Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
---|---|---|---|---|
NPC264317 | Betulinic Acid | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid | 220 | 1022 |
Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|
Recombinant Saccharomyces cerevisiae(overexpressed strain MO3) | Saccharomyces cerevisiae | ACE1 | Increase NP yield | n.a. | CRISPR/Cpf1 system was applied for ADY2 and ACE1 deletion, and overexpression of HES1, ACE1, CUP1, and SOD1 by genomic integration. | NPC264317 | Betulinic acid | n.a. | n.a. | 6.4-fold (YPD media) and increase accounts for over 60%(YPM media) |
PMID[33498600] |
Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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