Organism Name: Escherichia coli SC-LT [tryrBEc hmaSSc hmoSc leuDHBcopt]| Organism ID: | NPO41697 |
| Organism Name: | Escherichia coli SC-LT [tryrBEc hmaSSc hmoSc leuDHBcopt] |
| Native / Engineered Organism: | Engineered Organism |
| Matched Taxonomy Level: | Strain |
| Organism External ID: | NCBI_Taxonomy_ID[ n.a.] |
| Organism Synonyms: | |
| Genus: | Escherichia |
| Family: | Enterobacteriaceae |
| Kingdom: | n.a. |
| SuperKingdom: | Bacteria |
Individual Natural Products| Natural Product ID | Prefer Name (or InChiKey) | IUPAC Name | Number of Targets | Number of Activity Records |
|---|---|---|---|---|
| NPC313821 | lincomycin | n.a. | 30 | 367 |
NPs produced by Co-culture Organisms (for Co-culture organisms, the full organism list can be found HERE)| Organism Name | Producer Organism | Inducer Organism | NP ID | NP Name | Effect of Co-culture | Reference |
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NPs produced by Engineered Organisms (for Engineered organisms, the full organism list can be found HERE)| Organism Name | Parent Organism Name | Engineered Gene in Organism | Purpose of Engineering | Engineering Category | Engineering Description | NP ID | NP Name | NP Yeild of Parent Organism | NP Yeild of Engineered Organism | Yeild Change | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Escherichia coli SC-LT | Escherichia coli BW25113 | tryrBEc hmaSSc hmoSc leuDHBcopt | Heterologous expression; Increase NP yield | n.a. | A heterologous L-phg pathway was constructed by co-overexpressing the aromatic transaminase (tyrBEc) from E.coli, hydroxymandelate synthase (hmaSSc) and hydroxymandelate oxidase (hmoSc) from S. coelicolor, and a codon-optimized leucine dehydrogenase (leuDHBcopt) from Bacillus clausii | NPC313821 | lincomycin | n.a. | 0.23 mM (35.3 mg/L) L-phg | n.a. |
PMID[35024478] |
The Quantitative Compositions of NPs in Organism| Organism ID | NP ID | Organism Material Preparation | Organism Part | NP Quantity (Standard) | NP Quantity (Minimum) | NP Quantity (Maximum) | Quantity Unit | Reference |
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