Natural Product Target: Niemann-Pick C1 protein

Target ID:   NPT538
Target Name:   Niemann-Pick C1 protein
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ O15118]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC306902 Roemerine 3
NPC21429 Rutaecarpine 2
NPC208553 Paclitaxel 2
NPC173555 Digoxin 2
NPC215584 Elliptecine 2
NPC55304 Brefeldin A 2
NPC39426 Genistein 2
NPC196449 Calcimycin 2
NPC83287 Ouabain 2
NPC161571 Resveratrol 2
NPC161749 Daidzin 1
NPC215837 Streptonigrin 1
NPC66705 3-Benzoyl-7-Methoxychromen-2-One 1
NPC254010 2-Propan-2-Ylfuro[3,2-G]Chromen-7-One 1
NPC100329 n.a. 1
NPC298093 Rotenone 1
NPC161957 Aromaticin 1
NPC45165 Ononin 1
NPC254610 N-(2-Phenylethyl)-1,3-Benzodioxole-5-Carboxamide 1
NPC100887 Eupafolin 1
NPC299590 Triptolide 1
NPC164804 4-[(3S)-8,8-Dimethyl-3,4-Dihydro-2H-Pyrano[2,3-F]Chromen-3-Yl]Benzene-1,3-Diol 1
NPC470090 Sp-600125 1
NPC212866 Enniatin B 1
NPC254847 Emodin 1
NPC106334 Asterric Acid 1
NPC300776 (3S,4S)-4-[(3,4-Dimethoxyphenyl)Methyl]-3-[(4-Hydroxy-3-Methoxyphenyl)Methyl]Oxolan-2-One 1
NPC302950 Hesperetin 1
NPC167096 Ilepcimide 1
NPC64359 Sid24823998 1
NPC213761 Cinobufotalin 1
NPC257188 Xanthyletin 1
NPC12377 Cladrin 1
NPC116632 4',7-Dimethoxy-5-Hydroxygenistein 1
NPC306001 n.a. 1
NPC46451 Sanguinarium 1
NPC214036 Piplartine 1
NPC31171 Cytochalasin B 1
NPC116961 Loratadine 1
NPC180508 Pterostilbene 1
NPC475524 Cucurbitacin B 1
NPC268238 n.a. 1
NPC127447 Techtochrysin 1
NPC313449 Dequalinium 1
NPC185607 3-(3,4-Dimethoxyphenyl)-7-Methoxychromen-4-One 1
NPC471108 n.a. 1
NPC223336 1,2-Dimethoxyanthracene-9,10-Dione 1
NPC68441 Gossypol 1
NPC275960 Helenalin 1
NPC133162 Nortriptyline 1
NPC36836 Nicardipine 1
NPC187022 Emetine 1
NPC22783 2-(4-Hydroxyphenyl)Chromen-4-One 1
NPC72260 Digitoxin 1
NPC278556 Chrysin Dimethyl Ether 1
NPC135784 Aurin 1
NPC187145 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 1
NPC223354 Biochanin A, Dimethyl Ether 1
NPC231013 2,3-Dimethoxyxanthen-9-One 1
NPC72772 Strophanthidin 1
NPC32298 Flavone 1
NPC136330 Piperine 1
NPC320656 Sertraline 1
NPC189588 Digoxigenin 1
NPC26617 Thapsigargin 1
NPC231772 Acacetin 1
NPC73416 1-Hydroxy-2-Methoxyanthracene-9,10-Dione 1
NPC285635 2-Methoxyphenazine 1
NPC140840 Sulfuretin 1
NPC325983 Fonsecin 1
NPC191310 Diethyl 2,6-Dimethyl-4-Phenylpyridine-3,5-Dicarboxylate 1
NPC304954 Sid26657808 1
NPC234560 Daidzein 1
NPC73492 Cepharanthine 1
NPC288240 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 1
NPC2596 2-(4-Hydroxyphenyl)Ethyl 4-Methoxybenzoate 1
NPC328267 Fluoxetine 1
NPC192533 2-Anilinonaphthalene-1,4-Dione 1
NPC50898 Apigenin 1
NPC235165 5,7-Dihydroxy-6-Methoxy-2-Phenyl-2,3-Dihydrochromen-4-One 1
NPC73511 Prunetrin 1
NPC2771 4'-Methoxyflavone 1
NPC156222 Pectolinarigenin 1
NPC329631 Win-552122 1
NPC473206 Diphenyleneiodonium 1
NPC237946 Podofilox 1
NPC80710 Calycosin 1
NPC294409 Biochanin 1
NPC157931 n.a. 1
NPC240838 Anguidin 1
NPC197896 5-Hydroxy-3-(4-Hydroxyphenyl)-7-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxychromen-4-One 1
NPC150978 Angustibalin 1
NPC241498 Hispidulin 1
NPC295110 Digitoxigenin 1
NPC160972 Protoapigenone 1
NPC473417 Trifluoperazine 1
NPC204932 Catechol 1
NPC51695 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 1
NPC253574 (2R)-2-(2-Hydroxypropan-2-Yl)-2,3-Dihydrofuro[3,2-G]Chromen-7-One 1
NPC98028 Peucedanin 1
NPC295204 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate 1
NPC43787 Grinimibine 1
NPC207554 Tryptanthrin 1
NPC65517 Hydroquinone 1
NPC253703 Cycloheximide 1
NPC100079 Chelerythrine 1
NPC34864 Piceatannol 1

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4. Species Source: species sources that all natural products that have available activity against this target derived from.

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