Drug Information

Drug ID:  NPD7398
Drug Name:  Azilsartan Medoxomil
Molecular Formula:  C30H24N4O8
Canonical SMILES:  CCOc1nc2c(n1Cc1ccc(cc1)c1ccccc1c1[nH]oc(=O)n1)c(ccc2)C(=O)OCc1oc(=O)oc1C
Standard InCHI:  InChI=1S/C30H24N4O8/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26/h4-14H,3,15-16H2,1-2H3,(H,32,33,36)
Standard InCHIKey:  QJFSABGVXDWMIW-UHFFFAOYSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL; IUPHAR/BPS

  Structural Similarity Between NPASS Natural Products and NPD7398

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
Intermediate Similarity 0.7588 NPC243850
Intermediate Similarity 0.7184 NPC116622
Intermediate Similarity 0.7131 NPC244856
Intermediate Similarity 0.7126 NPC107836
Intermediate Similarity 0.7101 NPC236424
Intermediate Similarity 0.7101 NPC306644
Intermediate Similarity 0.7071 NPC274842
Intermediate Similarity 0.7021 NPC313345
Intermediate Similarity 0.7021 NPC314855
Intermediate Similarity 0.7021 NPC313796
Intermediate Similarity 0.7021 NPC315638
Intermediate Similarity 0.7 NPC263937
Intermediate Similarity 0.7 NPC94428
Remote Similarity 0.6992 NPC315545
Remote Similarity 0.6992 NPC314297
Remote Similarity 0.6978 NPC476341
Remote Similarity 0.6978 NPC282103
Remote Similarity 0.6947 NPC90415
Remote Similarity 0.6904 NPC314834
Remote Similarity 0.6895 NPC187145
Remote Similarity 0.6889 NPC243058
Remote Similarity 0.6867 NPC474916
Remote Similarity 0.686 NPC477979
Remote Similarity 0.6858 NPC203635
Remote Similarity 0.6835 NPC314648
Remote Similarity 0.6768 NPC303374
Remote Similarity 0.6763 NPC472842
Remote Similarity 0.6763 NPC123839
Remote Similarity 0.676 NPC157931
Remote Similarity 0.6758 NPC472207
Remote Similarity 0.6756 NPC256268
Remote Similarity 0.6753 NPC138370
Remote Similarity 0.6749 NPC31700
Remote Similarity 0.6747 NPC313884
Remote Similarity 0.6747 NPC98371
Remote Similarity 0.6735 NPC244425
Remote Similarity 0.6735 NPC15384
Remote Similarity 0.6733 NPC471762
Remote Similarity 0.6729 NPC472846
Remote Similarity 0.6711 NPC219848
Remote Similarity 0.6694 NPC62995
Remote Similarity 0.6693 NPC257851
Remote Similarity 0.6691 NPC279589
Remote Similarity 0.668 NPC266249
Remote Similarity 0.668 NPC282247
Remote Similarity 0.6679 NPC1203
Remote Similarity 0.6667 NPC471197
Remote Similarity 0.6667 NPC45048
Remote Similarity 0.6667 NPC66777
Remote Similarity 0.6667 NPC267811
Remote Similarity 0.6654 NPC63109
Remote Similarity 0.6653 NPC323969
Remote Similarity 0.664 NPC471198
Remote Similarity 0.6629 NPC74619
Remote Similarity 0.6599 NPC312645
Remote Similarity 0.6588 NPC132329
Remote Similarity 0.6569 NPC471944
Remote Similarity 0.6562 NPC329631
Remote Similarity 0.6556 NPC132539
Remote Similarity 0.6555 NPC81535
Remote Similarity 0.6543 NPC116555
Remote Similarity 0.6531 NPC242923
Remote Similarity 0.6525 NPC101350
Remote Similarity 0.652 NPC472099
Remote Similarity 0.6513 NPC124300
Remote Similarity 0.6512 NPC57453
Remote Similarity 0.6506 NPC478006
Remote Similarity 0.6504 NPC472098
Remote Similarity 0.6504 NPC118940
Remote Similarity 0.6502 NPC310618
Remote Similarity 0.6498 NPC79356
Remote Similarity 0.6498 NPC245916
Remote Similarity 0.6498 NPC102592
Remote Similarity 0.6493 NPC478083
Remote Similarity 0.6489 NPC291609
Remote Similarity 0.6486 NPC28945
Remote Similarity 0.6486 NPC235685
Remote Similarity 0.6486 NPC285343
Remote Similarity 0.648 NPC308906
Remote Similarity 0.6478 NPC89508
Remote Similarity 0.6475 NPC285192
Remote Similarity 0.6473 NPC179896
Remote Similarity 0.646 NPC478010
Remote Similarity 0.646 NPC478009
Remote Similarity 0.6456 NPC280638
Remote Similarity 0.6447 NPC84347
Remote Similarity 0.6444 NPC67288
Remote Similarity 0.6437 NPC471583
Remote Similarity 0.6437 NPC471782
Remote Similarity 0.6435 NPC88110
Remote Similarity 0.6426 NPC152768
Remote Similarity 0.6426 NPC148183
Remote Similarity 0.6423 NPC227824
Remote Similarity 0.6418 NPC314882
Remote Similarity 0.6417 NPC245756
Remote Similarity 0.6414 NPC198673
Remote Similarity 0.6407 NPC472843
Remote Similarity 0.6402 NPC311451
Remote Similarity 0.6402 NPC160898
Remote Similarity 0.6398 NPC278540
Remote Similarity 0.6395 NPC89987
Remote Similarity 0.6393 NPC82053
Remote Similarity 0.6393 NPC472845
Remote Similarity 0.6393 NPC238457
Remote Similarity 0.6392 NPC473506
Remote Similarity 0.6383 NPC196251
Remote Similarity 0.6383 NPC63199
Remote Similarity 0.6383 NPC111602
Remote Similarity 0.6383 NPC102338
Remote Similarity 0.6381 NPC472844
Remote Similarity 0.6378 NPC229893
Remote Similarity 0.6376 NPC471743
Remote Similarity 0.6375 NPC467439
Remote Similarity 0.6375 NPC168911
Remote Similarity 0.6371 NPC220852
Remote Similarity 0.6371 NPC141053
Remote Similarity 0.6371 NPC272458
Remote Similarity 0.6368 NPC160381
Remote Similarity 0.6368 NPC141612
Remote Similarity 0.6368 NPC17273
Remote Similarity 0.6368 NPC135601
Remote Similarity 0.6367 NPC87152
Remote Similarity 0.6367 NPC475631
Remote Similarity 0.6367 NPC74575
Remote Similarity 0.6367 NPC474905
Remote Similarity 0.6367 NPC476110
Remote Similarity 0.6367 NPC475600
Remote Similarity 0.6364 NPC280799
Remote Similarity 0.6364 NPC315467
Remote Similarity 0.636 NPC472116
Remote Similarity 0.636 NPC36405
Remote Similarity 0.636 NPC322064
Remote Similarity 0.6357 NPC473441
Remote Similarity 0.6357 NPC475303
Remote Similarity 0.6357 NPC131273
Remote Similarity 0.6357 NPC260434
Remote Similarity 0.6357 NPC475596
Remote Similarity 0.6352 NPC472119
Remote Similarity 0.6352 NPC21429
Remote Similarity 0.6349 NPC52254
Remote Similarity 0.6346 NPC327769
Remote Similarity 0.6346 NPC253675
Remote Similarity 0.6345 NPC192306
Remote Similarity 0.6345 NPC221100
Remote Similarity 0.6345 NPC234078
Remote Similarity 0.6344 NPC77101
Remote Similarity 0.6342 NPC475644
Remote Similarity 0.6342 NPC470486
Remote Similarity 0.6342 NPC471190
Remote Similarity 0.6342 NPC156003
Remote Similarity 0.6342 NPC471977
Remote Similarity 0.6341 NPC470280
Remote Similarity 0.634 NPC278434
Remote Similarity 0.6339 NPC220851
Remote Similarity 0.6339 NPC477788
Remote Similarity 0.6333 NPC472435
Remote Similarity 0.6332 NPC49547
Remote Similarity 0.6332 NPC935
Remote Similarity 0.6332 NPC473186
Remote Similarity 0.6332 NPC30456
Remote Similarity 0.6332 NPC267078
Remote Similarity 0.633 NPC270515
Remote Similarity 0.6329 NPC472097
Remote Similarity 0.6327 NPC277350
Remote Similarity 0.6326 NPC295452
Remote Similarity 0.6326 NPC171393
Remote Similarity 0.6324 NPC272174
Remote Similarity 0.6324 NPC472436
Remote Similarity 0.6318 NPC195314
Remote Similarity 0.6316 NPC477633
Remote Similarity 0.6314 NPC122436
Remote Similarity 0.6314 NPC76565
Remote Similarity 0.6314 NPC473666
Remote Similarity 0.631 NPC248601
Remote Similarity 0.631 NPC82070
Remote Similarity 0.6308 NPC474357
Remote Similarity 0.6307 NPC239954
Remote Similarity 0.6307 NPC102008
Remote Similarity 0.6305 NPC153980
Remote Similarity 0.6305 NPC6865
Remote Similarity 0.6303 NPC55493
Remote Similarity 0.6301 NPC244741
Remote Similarity 0.6299 NPC474896
Remote Similarity 0.6298 NPC470022
Remote Similarity 0.6298 NPC311858
Remote Similarity 0.6296 NPC54537
Remote Similarity 0.6295 NPC471192
Remote Similarity 0.6293 NPC160666
Remote Similarity 0.6292 NPC472068
Remote Similarity 0.6289 NPC475137
Remote Similarity 0.6289 NPC475498
Remote Similarity 0.6288 NPC148889
Remote Similarity 0.6287 NPC324091
Remote Similarity 0.6284 NPC158055
Remote Similarity 0.6284 NPC39370
Remote Similarity 0.6284 NPC170751
Remote Similarity 0.6284 NPC182222
Remote Similarity 0.6283 NPC473800
Remote Similarity 0.6276 NPC473178
Remote Similarity 0.6275 NPC31097

Drug Structure

External Identifiers

TTD   DCL000310
DrugBank   DB08822
ChEMBL   CHEMBL2028661
IUPHAR/BPS   6900
PharmaGKB  
KEGG Drug   D08865
PubChem CID   11238823
ChEBI   68845
CAS Number  863031-21-4

Drug Properties

Molecular Weight  568.16
ALogP  -0.0782
MLogP  3.44
XLogP  7.486
HDA  9
HBD  1
Rotatable Bonds  12
TPSA  139.57
RO5 Violation  1