Drug Information

Drug ID:  NPD6343
Drug Name:  Dextromoramide Tartrate
Molecular Formula:  C25H32N2O2.C4H6O6
Canonical SMILES:  OC(C(C(=O)O)O)C(=O)O.C[C@H](N1CCOCC1)CC(C(=O)N1CCCC1)(c1ccccc1)c1ccccc1
Standard InCHI:  InChI=1S/C25H32N2O2.C4H6O6/c1-21(26-16-18-29-19-17-26)20-25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27;5-1(3(7)8)2(6)4(9)10/h2-7,10-13,21H,8-9,14-20H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t21-;/m0./s1
Standard InCHIKey:  FSYOHJCDYPCNSD-BOXHHOBZSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD6343

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
Intermediate Similarity 0.8158 NPC473418
Intermediate Similarity 0.7674 NPC136453
Intermediate Similarity 0.7642 NPC473573
Intermediate Similarity 0.7615 NPC71933
Intermediate Similarity 0.7615 NPC89923
Intermediate Similarity 0.7615 NPC152850
Intermediate Similarity 0.7615 NPC105114
Intermediate Similarity 0.7615 NPC239990
Intermediate Similarity 0.7591 NPC161069
Intermediate Similarity 0.7583 NPC158854
Intermediate Similarity 0.7542 NPC167336
Intermediate Similarity 0.7444 NPC157311
Intermediate Similarity 0.7388 NPC8761
Intermediate Similarity 0.7388 NPC473962
Intermediate Similarity 0.7388 NPC44805
Intermediate Similarity 0.7376 NPC138775
Intermediate Similarity 0.7328 NPC79698
Intermediate Similarity 0.7323 NPC220698
Intermediate Similarity 0.7293 NPC473322
Intermediate Similarity 0.728 NPC33742
Intermediate Similarity 0.7231 NPC213126
Intermediate Similarity 0.7231 NPC169485
Intermediate Similarity 0.7231 NPC84281
Intermediate Similarity 0.7231 NPC317474
Intermediate Similarity 0.7231 NPC291027
Intermediate Similarity 0.7226 NPC79465
Intermediate Similarity 0.7226 NPC474811
Intermediate Similarity 0.7226 NPC293377
Intermediate Similarity 0.7226 NPC118099
Intermediate Similarity 0.7226 NPC90194
Intermediate Similarity 0.7226 NPC273907
Intermediate Similarity 0.7226 NPC474787
Intermediate Similarity 0.7226 NPC49577
Intermediate Similarity 0.7226 NPC475598
Intermediate Similarity 0.7226 NPC475318
Intermediate Similarity 0.7226 NPC474855
Intermediate Similarity 0.7226 NPC76785
Intermediate Similarity 0.7226 NPC9687
Intermediate Similarity 0.7226 NPC260045
Intermediate Similarity 0.7226 NPC151706
Intermediate Similarity 0.7226 NPC476102
Intermediate Similarity 0.7209 NPC200964
Intermediate Similarity 0.72 NPC35850
Intermediate Similarity 0.72 NPC276949
Intermediate Similarity 0.719 NPC45033
Intermediate Similarity 0.7185 NPC255447
Intermediate Similarity 0.7165 NPC315276
Intermediate Similarity 0.7165 NPC14672
Intermediate Similarity 0.7165 NPC285926
Intermediate Similarity 0.7154 NPC314192
Intermediate Similarity 0.7113 NPC5620
Intermediate Similarity 0.7113 NPC209509
Intermediate Similarity 0.7111 NPC200589
Intermediate Similarity 0.7111 NPC69496
Intermediate Similarity 0.7109 NPC470545
Intermediate Similarity 0.708 NPC233910
Intermediate Similarity 0.708 NPC245836
Intermediate Similarity 0.7077 NPC302169
Intermediate Similarity 0.7068 NPC474847
Intermediate Similarity 0.7063 NPC262077
Intermediate Similarity 0.7059 NPC126458
Intermediate Similarity 0.7054 NPC470546
Intermediate Similarity 0.7045 NPC175726
Intermediate Similarity 0.7045 NPC474082
Intermediate Similarity 0.7045 NPC6975
Intermediate Similarity 0.7031 NPC470544
Intermediate Similarity 0.7021 NPC269398
Intermediate Similarity 0.7021 NPC263493
Intermediate Similarity 0.7008 NPC246904
Intermediate Similarity 0.7 NPC476133
Intermediate Similarity 0.7 NPC178662
Intermediate Similarity 0.7 NPC98424
Intermediate Similarity 0.7 NPC92784
Intermediate Similarity 0.7 NPC470884
Remote Similarity 0.6992 NPC55529
Remote Similarity 0.6983 NPC474974
Remote Similarity 0.6983 NPC71140
Remote Similarity 0.6947 NPC27833
Remote Similarity 0.6923 NPC476978
Remote Similarity 0.6923 NPC256452
Remote Similarity 0.6918 NPC129666
Remote Similarity 0.6912 NPC111428
Remote Similarity 0.6906 NPC248283
Remote Similarity 0.6894 NPC202521
Remote Similarity 0.6894 NPC71684
Remote Similarity 0.6891 NPC322598
Remote Similarity 0.6887 NPC113946
Remote Similarity 0.6879 NPC316906
Remote Similarity 0.6821 NPC29285
Remote Similarity 0.6818 NPC476990
Remote Similarity 0.6818 NPC231986
Remote Similarity 0.681 NPC470926
Remote Similarity 0.6809 NPC471265
Remote Similarity 0.6809 NPC471264
Remote Similarity 0.6807 NPC472258
Remote Similarity 0.6797 NPC73644
Remote Similarity 0.6781 NPC145113
Remote Similarity 0.6779 NPC66936
Remote Similarity 0.6779 NPC122590
Remote Similarity 0.6774 NPC473498
Remote Similarity 0.6765 NPC65310
Remote Similarity 0.6754 NPC17497
Remote Similarity 0.6754 NPC305602
Remote Similarity 0.6741 NPC285394
Remote Similarity 0.6741 NPC222466
Remote Similarity 0.6739 NPC179224
Remote Similarity 0.6716 NPC252878
Remote Similarity 0.6716 NPC26285
Remote Similarity 0.6713 NPC163392
Remote Similarity 0.6713 NPC469560
Remote Similarity 0.6713 NPC239762
Remote Similarity 0.6691 NPC130309
Remote Similarity 0.6691 NPC101719
Remote Similarity 0.669 NPC471123
Remote Similarity 0.669 NPC52748
Remote Similarity 0.669 NPC127741
Remote Similarity 0.6687 NPC475427
Remote Similarity 0.6667 NPC329761
Remote Similarity 0.6667 NPC46427
Remote Similarity 0.6667 NPC225648
Remote Similarity 0.6667 NPC472106
Remote Similarity 0.6667 NPC469666
Remote Similarity 0.6645 NPC472120
Remote Similarity 0.6645 NPC472101
Remote Similarity 0.6643 NPC257390
Remote Similarity 0.6641 NPC269340
Remote Similarity 0.6622 NPC471821
Remote Similarity 0.6622 NPC105717
Remote Similarity 0.6622 NPC471820
Remote Similarity 0.6622 NPC240848
Remote Similarity 0.6621 NPC139326
Remote Similarity 0.6621 NPC186284
Remote Similarity 0.6621 NPC197682
Remote Similarity 0.6621 NPC22082
Remote Similarity 0.66 NPC162104
Remote Similarity 0.6597 NPC307357
Remote Similarity 0.6597 NPC268841
Remote Similarity 0.6597 NPC46098
Remote Similarity 0.6596 NPC313663
Remote Similarity 0.6577 NPC2501
Remote Similarity 0.6577 NPC283783
Remote Similarity 0.6575 NPC314388
Remote Similarity 0.6575 NPC315283
Remote Similarity 0.6562 NPC96901
Remote Similarity 0.656 NPC476198
Remote Similarity 0.6558 NPC104345
Remote Similarity 0.6552 NPC168113
Remote Similarity 0.6552 NPC150712
Remote Similarity 0.6541 NPC310467
Remote Similarity 0.6538 NPC472117
Remote Similarity 0.6538 NPC176983
Remote Similarity 0.6531 NPC471680
Remote Similarity 0.6531 NPC316008
Remote Similarity 0.6531 NPC313867
Remote Similarity 0.6525 NPC246913
Remote Similarity 0.6519 NPC279527
Remote Similarity 0.6519 NPC214960
Remote Similarity 0.6516 NPC276085
Remote Similarity 0.6515 NPC239357
Remote Similarity 0.6504 NPC474582
Remote Similarity 0.6486 NPC314358
Remote Similarity 0.6484 NPC292758
Remote Similarity 0.6484 NPC65855
Remote Similarity 0.6479 NPC287401
Remote Similarity 0.6474 NPC309531
Remote Similarity 0.6474 NPC472102
Remote Similarity 0.6471 NPC473661
Remote Similarity 0.6466 NPC169328
Remote Similarity 0.646 NPC285622
Remote Similarity 0.646 NPC137627
Remote Similarity 0.6458 NPC478140
Remote Similarity 0.6458 NPC68865
Remote Similarity 0.6452 NPC329375
Remote Similarity 0.6452 NPC222029
Remote Similarity 0.6449 NPC4974
Remote Similarity 0.6447 NPC286551
Remote Similarity 0.6447 NPC473341
Remote Similarity 0.6444 NPC316582
Remote Similarity 0.6443 NPC135121
Remote Similarity 0.6443 NPC16188
Remote Similarity 0.6438 NPC315051
Remote Similarity 0.6433 NPC471052
Remote Similarity 0.6433 NPC471051
Remote Similarity 0.6433 NPC471053
Remote Similarity 0.6429 NPC474695
Remote Similarity 0.6429 NPC165726
Remote Similarity 0.6429 NPC213969
Remote Similarity 0.6419 NPC477217
Remote Similarity 0.6419 NPC201244
Remote Similarity 0.6414 NPC132636
Remote Similarity 0.6414 NPC281104
Remote Similarity 0.6408 NPC246079
Remote Similarity 0.6395 NPC251439
Remote Similarity 0.6395 NPC176226
Remote Similarity 0.6395 NPC470301
Remote Similarity 0.6387 NPC297145
Remote Similarity 0.6387 NPC197743
Remote Similarity 0.6383 NPC300315
Remote Similarity 0.6382 NPC233702
Remote Similarity 0.6382 NPC473329

Drug Structure

External Identifiers

TTD  
DrugBank  
ChEMBL  
IUPHAR/BPS  
PharmaGKB  
KEGG Drug  
PubChem CID  
ChEBI  
CAS Number  

Drug Properties

Molecular Weight  392.25
ALogP  -1.5886
MLogP  3.77
XLogP  6.767
HDA  4
HBD  0
Rotatable Bonds  8
TPSA  32.78
RO5 Violation  1