Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT19 | Organism | Escherichia coli | Escherichia coli | MIC | > | 32 | ug/ml | 17845000 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | = | 6 | ug/ml | 17845000 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | = | 1.5 | ug/ml | 17845000 |
NPT17 | Organism | Staphylococcus epidermidis | Staphylococcus epidermidis | MIC | = | 1.3 | ug/ml | 17845000 |
NPT17 | Organism | Staphylococcus epidermidis | Staphylococcus epidermidis | MIC | = | 0.8 | ug/ml | 17845000 |
NPT1118 | Organism | Streptococcus pneumoniae | Streptococcus pneumoniae | MIC | = | 8 | ug/ml | 17845000 |
NPT1118 | Organism | Streptococcus pneumoniae | Streptococcus pneumoniae | MIC | = | 6 | ug/ml | 17845000 |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 3 | ug/ml | 17845000 |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 1.5 | ug/ml | 17845000 |
NPT1122 | Organism | Haemophilus influenzae | Haemophilus influenzae | MIC | = | 12 | ug/ml | 17845000 |
NPT1122 | Organism | Haemophilus influenzae | Haemophilus influenzae | MIC | = | 16 | ug/ml | 17845000 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC477485 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.9726 | High Similarity | NPC477486 |
0.9726 | High Similarity | NPC477484 |
0.6742 | Remote Similarity | NPC477487 |
0.641 | Remote Similarity | NPC325550 |
0.641 | Remote Similarity | NPC326524 |
0.641 | Remote Similarity | NPC329003 |
0.6395 | Remote Similarity | NPC288086 |
0.6353 | Remote Similarity | NPC469836 |
0.6333 | Remote Similarity | NPC162741 |
0.6333 | Remote Similarity | NPC91332 |
0.6322 | Remote Similarity | NPC217095 |
0.6322 | Remote Similarity | NPC264417 |
0.6304 | Remote Similarity | NPC471595 |
0.6282 | Remote Similarity | NPC321030 |
0.625 | Remote Similarity | NPC64971 |
0.6207 | Remote Similarity | NPC469835 |
0.62 | Remote Similarity | NPC175614 |
0.6196 | Remote Similarity | NPC469838 |
0.6196 | Remote Similarity | NPC469833 |
0.6173 | Remote Similarity | NPC316674 |
0.6145 | Remote Similarity | NPC83965 |
0.6118 | Remote Similarity | NPC103712 |
0.6118 | Remote Similarity | NPC291196 |
0.6111 | Remote Similarity | NPC474833 |
0.6091 | Remote Similarity | NPC5485 |
0.6081 | Remote Similarity | NPC288381 |
0.6081 | Remote Similarity | NPC20934 |
0.6044 | Remote Similarity | NPC471597 |
0.6023 | Remote Similarity | NPC160540 |
0.6 | Remote Similarity | NPC278202 |
0.5982 | Remote Similarity | NPC315652 |
0.5982 | Remote Similarity | NPC7905 |
0.5978 | Remote Similarity | NPC472948 |
0.5963 | Remote Similarity | NPC122926 |
0.5963 | Remote Similarity | NPC113012 |
0.5957 | Remote Similarity | NPC144415 |
0.5952 | Remote Similarity | NPC137163 |
0.5949 | Remote Similarity | NPC192843 |
0.5949 | Remote Similarity | NPC281230 |
0.5941 | Remote Similarity | NPC189764 |
0.5929 | Remote Similarity | NPC27413 |
0.5929 | Remote Similarity | NPC271621 |
0.5929 | Remote Similarity | NPC59751 |
0.5921 | Remote Similarity | NPC188341 |
0.5921 | Remote Similarity | NPC49494 |
0.5918 | Remote Similarity | NPC159369 |
0.5918 | Remote Similarity | NPC39290 |
0.5905 | Remote Similarity | NPC469598 |
0.5897 | Remote Similarity | NPC242930 |
0.5895 | Remote Similarity | NPC477199 |
0.5888 | Remote Similarity | NPC154601 |
0.5888 | Remote Similarity | NPC271269 |
0.5882 | Remote Similarity | NPC193029 |
0.5882 | Remote Similarity | NPC473357 |
0.5862 | Remote Similarity | NPC477455 |
0.5862 | Remote Similarity | NPC94743 |
0.5862 | Remote Similarity | NPC291062 |
0.5851 | Remote Similarity | NPC180363 |
0.5851 | Remote Similarity | NPC65930 |
0.5851 | Remote Similarity | NPC73310 |
0.5851 | Remote Similarity | NPC473712 |
0.5851 | Remote Similarity | NPC145914 |
0.5851 | Remote Similarity | NPC329829 |
0.5851 | Remote Similarity | NPC131002 |
0.5851 | Remote Similarity | NPC473529 |
0.5851 | Remote Similarity | NPC475159 |
0.5851 | Remote Similarity | NPC94875 |
0.5851 | Remote Similarity | NPC474312 |
0.5851 | Remote Similarity | NPC473780 |
0.5851 | Remote Similarity | NPC11332 |
0.5843 | Remote Similarity | NPC474321 |
0.5842 | Remote Similarity | NPC192066 |
0.5842 | Remote Similarity | NPC3568 |
0.5842 | Remote Similarity | NPC17290 |
0.5842 | Remote Similarity | NPC256570 |
0.5833 | Remote Similarity | NPC296436 |
0.5833 | Remote Similarity | NPC251330 |
0.5833 | Remote Similarity | NPC176215 |
0.5825 | Remote Similarity | NPC265662 |
0.5814 | Remote Similarity | NPC249713 |
0.5814 | Remote Similarity | NPC263382 |
0.5814 | Remote Similarity | NPC125578 |
0.5814 | Remote Similarity | NPC146376 |
0.5814 | Remote Similarity | NPC474812 |
0.5806 | Remote Similarity | NPC47653 |
0.58 | Remote Similarity | NPC146852 |
0.5794 | Remote Similarity | NPC472616 |
0.5789 | Remote Similarity | NPC261571 |
0.5789 | Remote Similarity | NPC253801 |
0.5789 | Remote Similarity | NPC476190 |
0.5784 | Remote Similarity | NPC205546 |
0.5784 | Remote Similarity | NPC50902 |
0.5784 | Remote Similarity | NPC233273 |
0.5783 | Remote Similarity | NPC477707 |
0.578 | Remote Similarity | NPC140251 |
0.578 | Remote Similarity | NPC307903 |
0.5776 | Remote Similarity | NPC473808 |
0.5773 | Remote Similarity | NPC204686 |
0.5773 | Remote Similarity | NPC473687 |
0.5773 | Remote Similarity | NPC219498 |
0.5773 | Remote Similarity | NPC477010 |
0.5773 | Remote Similarity | NPC134807 |
0.5773 | Remote Similarity | NPC134885 |
0.5773 | Remote Similarity | NPC477015 |
0.5773 | Remote Similarity | NPC210218 |
0.5773 | Remote Similarity | NPC308412 |
0.575 | Remote Similarity | NPC52012 |
0.5747 | Remote Similarity | NPC280065 |
0.5747 | Remote Similarity | NPC94488 |
0.5747 | Remote Similarity | NPC16964 |
0.5747 | Remote Similarity | NPC45060 |
0.5747 | Remote Similarity | NPC471022 |
0.5747 | Remote Similarity | NPC475004 |
0.5747 | Remote Similarity | NPC262673 |
0.5743 | Remote Similarity | NPC61275 |
0.5741 | Remote Similarity | NPC472615 |
0.5741 | Remote Similarity | NPC201128 |
0.5739 | Remote Similarity | NPC296361 |
0.5732 | Remote Similarity | NPC130807 |
0.573 | Remote Similarity | NPC314678 |
0.5729 | Remote Similarity | NPC475706 |
0.5729 | Remote Similarity | NPC163093 |
0.5729 | Remote Similarity | NPC156804 |
0.5728 | Remote Similarity | NPC8098 |
0.5728 | Remote Similarity | NPC183449 |
0.5728 | Remote Similarity | NPC197294 |
0.5727 | Remote Similarity | NPC474725 |
0.5714 | Remote Similarity | NPC477457 |
0.5714 | Remote Similarity | NPC476269 |
0.5714 | Remote Similarity | NPC477012 |
0.5714 | Remote Similarity | NPC477456 |
0.5714 | Remote Similarity | NPC472614 |
0.5701 | Remote Similarity | NPC474563 |
0.57 | Remote Similarity | NPC166554 |
0.5698 | Remote Similarity | NPC472266 |
0.5698 | Remote Similarity | NPC243272 |
0.5698 | Remote Similarity | NPC127091 |
0.5698 | Remote Similarity | NPC22101 |
0.5698 | Remote Similarity | NPC148192 |
0.5698 | Remote Similarity | NPC473752 |
0.5698 | Remote Similarity | NPC104537 |
0.5698 | Remote Similarity | NPC271921 |
0.5698 | Remote Similarity | NPC330426 |
0.5696 | Remote Similarity | NPC281590 |
0.5686 | Remote Similarity | NPC23454 |
0.5686 | Remote Similarity | NPC473314 |
0.5686 | Remote Similarity | NPC35269 |
0.5686 | Remote Similarity | NPC70323 |
0.5686 | Remote Similarity | NPC262312 |
0.5686 | Remote Similarity | NPC477241 |
0.5682 | Remote Similarity | NPC42526 |
0.5679 | Remote Similarity | NPC325734 |
0.567 | Remote Similarity | NPC473669 |
0.567 | Remote Similarity | NPC235809 |
0.567 | Remote Similarity | NPC470400 |
0.567 | Remote Similarity | NPC477014 |
0.567 | Remote Similarity | NPC100921 |
0.567 | Remote Similarity | NPC103284 |
0.567 | Remote Similarity | NPC39167 |
0.567 | Remote Similarity | NPC292809 |
0.567 | Remote Similarity | NPC132496 |
0.567 | Remote Similarity | NPC329615 |
0.567 | Remote Similarity | NPC25764 |
0.567 | Remote Similarity | NPC110710 |
0.567 | Remote Similarity | NPC475268 |
0.567 | Remote Similarity | NPC322529 |
0.567 | Remote Similarity | NPC77871 |
0.567 | Remote Similarity | NPC9678 |
0.567 | Remote Similarity | NPC286338 |
0.567 | Remote Similarity | NPC473651 |
0.567 | Remote Similarity | NPC39279 |
0.567 | Remote Similarity | NPC82795 |
0.567 | Remote Similarity | NPC1083 |
0.567 | Remote Similarity | NPC473478 |
0.567 | Remote Similarity | NPC319036 |
0.567 | Remote Similarity | NPC231009 |
0.567 | Remote Similarity | NPC477018 |
0.567 | Remote Similarity | NPC120398 |
0.567 | Remote Similarity | NPC107986 |
0.567 | Remote Similarity | NPC283085 |
0.567 | Remote Similarity | NPC66346 |
0.567 | Remote Similarity | NPC223871 |
0.567 | Remote Similarity | NPC182383 |
0.567 | Remote Similarity | NPC329838 |
0.567 | Remote Similarity | NPC473156 |
0.567 | Remote Similarity | NPC202055 |
0.567 | Remote Similarity | NPC477013 |
0.567 | Remote Similarity | NPC471567 |
0.567 | Remote Similarity | NPC473671 |
0.5667 | Remote Similarity | NPC227396 |
0.5667 | Remote Similarity | NPC264178 |
0.5663 | Remote Similarity | NPC321838 |
0.5663 | Remote Similarity | NPC29468 |
0.566 | Remote Similarity | NPC313234 |
0.5658 | Remote Similarity | NPC225974 |
0.5652 | Remote Similarity | NPC474818 |
0.5652 | Remote Similarity | NPC51809 |
0.5652 | Remote Similarity | NPC125365 |
0.5652 | Remote Similarity | NPC176329 |
0.5652 | Remote Similarity | NPC49302 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC477485 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.625 | Remote Similarity | NPD818 | Approved |
0.625 | Remote Similarity | NPD819 | Approved |
0.5929 | Remote Similarity | NPD7505 | Discontinued |
0.5909 | Remote Similarity | NPD7116 | Clinical (unspecified phase) |
0.5625 | Remote Similarity | NPD7601 | Clinical (unspecified phase) |
PubChem CID   | 23642821 |
ChEMBL   | CHEMBL400963 |
ZINC   |
Molecular Weight:   | 335.25 |
ALogP:   | -1.9057 |
MLogP:   | 3.22 |
XLogP:   | 6.386 |
# Rotatable Bonds:   | 16 |
Polar Surface Area:   | 58.89 |
# H-Bond Aceptor:   | 4 |
# H-Bond Donor:   | 1 |
# Rings:   | 1 |
# Heavy Atoms:   | 24 |