Target ID |
Target Type |
Target Name |
Target Organism |
Activity Type |
Activity Relation |
Value |
Unit |
Reference |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
4200 |
nM |
8691450 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Ki |
= |
7000 |
nM |
8691450 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
2.7 |
min |
3351858 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
260 |
nM |
11294382 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED20 |
= |
3.5 |
mg/kg |
11294382 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
ED20 |
> |
10 |
mg/kg |
11294382 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
34910 |
nM |
12873513 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
9800 |
U (mg of protein)-1 |
11140725 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
1912 |
U (mg of protein)-1 |
11140725 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
21 |
U (mg of protein)-1 |
11140725 |
NPT6 |
Organism |
Plasmodium falciparum |
Plasmodium falciparum |
IC50 |
>= |
150000 |
nM |
17149876 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
7820 |
nM |
17379526 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Inhibition |
= |
93.8 |
% |
17379526 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
42240 |
nM |
17497807 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
2200 |
nM |
17346963 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Inhibition |
= |
96.3 |
% |
17692432 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
24400 |
nM |
17692432 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
10340 |
nM |
17706325 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
42.3 |
% |
18835711 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
84 |
% |
18819730 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
34910 |
nM |
16309309 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
240 |
nM |
9461655 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
230 |
nM |
9461655 |
NPT613 |
Individual Protein |
Solute carrier family 22 member 1 |
Homo sapiens |
Inhibition |
= |
7.7 |
% |
18788725 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
21800 |
nM |
18722771 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
11400 |
nM |
18722771 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
1600 |
nM |
2723668 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
2000 |
nM |
18512985 |
NPT580 |
Organism |
Trypanosoma cruzi |
Trypanosoma cruzi |
Activity |
= |
7 |
% |
11975490 |
NPT580 |
Organism |
Trypanosoma cruzi |
Trypanosoma cruzi |
Activity |
= |
10.9 |
|
11975490 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
24200 |
nM |
10425142 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
9820 |
nM |
16872152 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
7450 |
nM |
15730241 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
2000 |
nM |
18606546 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
90 |
% |
18063225 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
77 |
% |
19064319 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Activity |
= |
94 |
% |
19362850 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
23500 |
nM |
19362850 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Activity |
= |
140 |
nM/s |
19388706 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Activity |
= |
120 |
nM/s |
19388706 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Activity |
= |
28 |
nM/s |
19388706 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
-77.5 |
% |
19962217 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
-66.4 |
% |
19962217 |
NPT4394 |
Individual Protein |
Xanthine dehydrogenase/oxidase |
Rattus norvegicus |
IC50 |
= |
21200 |
nM |
19673490 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
2300 |
nM |
19783139 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
-3.3 |
% |
19783139 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
35.9 |
% |
19783139 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
180 |
nM |
19476336 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
86 |
% |
20399654 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
3000 |
nM |
20384317 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
80 |
% |
20542691 |
NPT4896 |
Individual Protein |
Purine nucleoside phosphorylase |
Mycobacterium tuberculosis |
Kd |
= |
1000000 |
nM |
20570524 |
NPT483 |
Individual Protein |
Prelamin-A/C |
Homo sapiens |
Potency |
= |
6309.6 |
nM |
PubChem BioAssay data set |
NPT537 |
Individual Protein |
Ras-related protein Rab-9A |
Homo sapiens |
Potency |
= |
1000 |
nM |
PubChem BioAssay data set |
NPT93 |
Individual Protein |
Survival motor neuron protein |
Homo sapiens |
Potency |
= |
1000 |
nM |
PubChem BioAssay data set |
NPT210 |
Individual Protein |
Thyroid stimulating hormone receptor |
Homo sapiens |
Potency |
= |
5011.9 |
nM |
PubChem BioAssay data set |
NPT58 |
Individual Protein |
Bloom syndrome protein |
Homo sapiens |
Potency |
= |
398.1 |
nM |
PubChem BioAssay data set |
NPT347 |
Cell Line |
Lymphoblastoid cells |
Homo sapiens |
Potency |
= |
15848.9 |
nM |
PubChem BioAssay data set |
NPT4394 |
Individual Protein |
Xanthine dehydrogenase/oxidase |
Rattus norvegicus |
IC50 |
= |
753 |
nM |
21163661 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
730 |
nM |
21163661 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
730 |
nM |
21163661 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
3000 |
nM |
21174408 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
8300 |
nM |
21353569 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
3981.1 |
nM |
PubChem BioAssay data set |
NPT5 |
Individual Protein |
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Homo sapiens |
Potency |
|
25.1 |
nM |
PubChem BioAssay data set |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
1900 |
nM |
21345544 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
42 |
% |
21723119 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
8300 |
nM |
21862335 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Activity |
= |
3.19 |
nM |
21862335 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Activity |
= |
2.93 |
nM |
21862335 |
NPT32 |
Organism |
Mus musculus |
Mus musculus |
Activity |
= |
2.17 |
nM |
21862335 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
20 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
69 |
nmol/min |
21930379 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
184 |
% |
22483591 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
5700 |
nM |
22483591 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Inhibition |
= |
100 |
% |
22483591 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
0.53 |
ug/ml |
22677314 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
8500 |
nM |
22901670 |
NPT10 |
Individual Protein |
Geminin |
Homo sapiens |
Potency |
|
92 |
nM |
PubChem BioAssay data set |
NPT539 |
Individual Protein |
Cellular tumor antigen p53 |
Homo sapiens |
Potency |
|
31622.8 |
nM |
PubChem BioAssay data set |
NPT152 |
Individual Protein |
Nuclear factor erythroid 2-related factor 2 |
Homo sapiens |
Potency |
|
74978 |
nM |
PubChem BioAssay data set |
NPT102 |
Individual Protein |
Interleukin-8 |
Homo sapiens |
Potency |
|
74978 |
nM |
PubChem BioAssay data set |
NPT1417 |
Individual Protein |
Transcriptional regulator ERG |
Homo sapiens |
Potency |
|
794.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
41 |
% |
23078966 |
NPT622 |
Individual Protein |
Solute carrier organic anion transporter family member 2B1 |
Homo sapiens |
Inhibition |
= |
8.4 |
% |
22541068 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
10.8 |
% |
22541068 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
-35.6 |
% |
22541068 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
130 |
% |
23122864 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
177 |
% |
23122864 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
4190 |
nM |
23122864 |
NPT2933 |
Individual Protein |
Aldehyde oxidase |
Oryctolagus cuniculus |
Inhibition |
= |
18 |
% |
21476569 |
NPT43 |
Individual Protein |
Tyrosinase |
Agaricus bisporus |
Inhibition |
= |
4 |
% |
21476569 |
NPT2933 |
Individual Protein |
Aldehyde oxidase |
Oryctolagus cuniculus |
IC50 |
> |
1000000 |
nM |
21476569 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
17000 |
nM |
21476569 |
NPT43 |
Individual Protein |
Tyrosinase |
Agaricus bisporus |
IC50 |
> |
1000000 |
nM |
21476569 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
-77 |
% |
10.1007/s00044-010-9444-9 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
-83 |
% |
10.1007/s00044-009-9280-y |
NPT4394 |
Individual Protein |
Xanthine dehydrogenase/oxidase |
Rattus norvegicus |
IC50 |
= |
6000 |
nM |
23177727 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
4200 |
nM |
23265878 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
5804.8 |
nM |
PubChem BioAssay data set |
NPT861 |
Individual Protein |
Isocitrate dehydrogenase [NADP] cytoplasmic |
Homo sapiens |
Potency |
|
25929 |
nM |
PubChem BioAssay data set |
NPT160 |
Individual Protein |
TAR DNA-binding protein 43 |
Homo sapiens |
Potency |
|
35481.3 |
nM |
PubChem BioAssay data set |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
1.6 |
ug/ml |
23851116 |
NPT2 |
Others |
Unspecified |
|
Inhibition |
= |
51 |
% |
23954239 |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
54 |
% |
24090915 |
NPT580 |
Organism |
Trypanosoma cruzi |
Trypanosoma cruzi |
IC50 |
= |
9620 |
nM |
24090917 |
NPT73 |
Individual Protein |
Solute carrier organic anion transporter family member 1B1 |
Homo sapiens |
Inhibition |
= |
68.8 |
% |
23571415 |
NPT72 |
Individual Protein |
Solute carrier organic anion transporter family member 1B3 |
Homo sapiens |
Inhibition |
= |
84.36 |
% |
23571415 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
11100 |
nM |
24388807 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
11230 |
nM |
24556143 |
NPT614 |
Tissue |
Plasma |
Rattus norvegicus |
Activity |
= |
94 |
% |
24508129 |
NPT29 |
Organism |
Rattus norvegicus |
Rattus norvegicus |
Activity |
= |
87 |
% |
24508129 |
NPT2 |
Others |
Unspecified |
|
Potency |
|
13.3 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
10.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
6308.8 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
266 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
37.6 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
27945.9 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
1.5 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
22384.5 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
44663 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
15 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
5623.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Activity |
= |
49 |
% |
24871900 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
5000 |
nM |
2778 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Inhibition |
= |
100 |
% |
2778 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Ki |
= |
2600 |
nM |
2778 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
Ki |
= |
1000 |
nM |
2778 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
3000 |
nM |
926119 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Ki |
= |
100 |
nM |
25060641 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Ki |
= |
7300 |
nM |
25019478 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
2000 |
nM |
25245672 |
NPT2 |
Others |
Unspecified |
|
AC50 |
|
28183.8 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
56227.4 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
Potency |
|
15089 |
nM |
PubChem BioAssay data set |
NPT2 |
Others |
Unspecified |
|
AC50 |
|
1778.3 |
nM |
PubChem BioAssay data set |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
2900 |
nM |
26022844 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
Ki |
= |
1550 |
nM |
26712096 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
200 |
nM |
26762836 |
NPT2 |
Others |
Unspecified |
|
IC50 |
= |
3740 |
nM |
26774578 |
NPT1310 |
Individual Protein |
Xanthine dehydrogenase |
Bos taurus |
IC50 |
= |
44000 |
nM |
27133595 |
NPT967 |
Individual Protein |
Xanthine dehydrogenase |
Homo sapiens |
IC50 |
= |
950 |
nM |
27162124 |