Natural Product: NPC295898

Natural Product ID:  NPC295898
Common Name:   n.a.
IUPAC Name:  
Synonyms:  
Molecular Formula:   C16H12N2O3
Standard InCHIKey:  OXLYRYAVJWCSDD-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C16H12N2O3/c1-17-6-5-11-10-4-3-9(21-2)7-12(10)18-15(11)13(17)8-14(19)16(18)20/h3-8H,1-2H3
Canonical SMILES:  COc1ccc2c(c1)n1c(=O)c(=O)cc3c1c2ccn3C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO20383 Stenocereus thurberi Species Cactaceae Eukaryota UNPD*
NPO11530 Heterosigma akashiwo Species Chattonellaceae Eukaryota UNPD*
NPO11072 Geigeria schinzii Species Asteraceae Eukaryota UNPD*
NPO8640 Nemuaron humboldtii Species Atherospermataceae Eukaryota UNPD*
NPO12988 Blainvillea latifolia Species Asteraceae Eukaryota UNPD*
NPO14280 Helichrysum angustifolium Species Asteraceae Eukaryota UNPD*
NPO6014 Goniothalamus undulatus Species Annonaceae Eukaryota UNPD*
NPO20318 Acinetobacter baumannii Species Moraxellaceae Bacteria UNPD*
NPO13494 Prosopis kuntzei Species Fabaceae Eukaryota UNPD*
NPO893 Helichrysum sutherlandii Species Asteraceae Eukaryota UNPD*
NPO8220 Russula sardonia Species Russulaceae Eukaryota UNPD*
NPO13692 Leontice kiangnanensis Species Berberidaceae Eukaryota UNPD*
NPO6626 Pteris spinulosa Species Pteridaceae Eukaryota UNPD*
NPO22888 Lophiostoma vaginatispora Species Lophiostomataceae Eukaryota UNPD*
NPO2084 Acinetobacter calcoaceticus Species Moraxellaceae Bacteria UNPD*
NPO13604 Dermocybe cardinalis Species Cortinariaceae Eukaryota UNPD*
NPO12026 Papaver radicatum Species Papaveraceae Eukaryota UNPD*
NPO5401 Monanchora unguiculata Species Crambeidae Eukaryota UNPD*
NPO3924 Penicillium alutaceum Species Aspergillaceae Eukaryota UNPD*
NPO9965 Eurycoma longifolia Species Simaroubaceae Eukaryota UNPD*
NPO8820 Lophocereus marginatus Species Cactaceae Eukaryota UNPD*
NPO14602 Vitex negundo Species Lamiaceae Eukaryota UNPD*
NPO12890 Ophryosporus charua Species Asteraceae Eukaryota UNPD*
NPO9644 Euphorbia resinifera Species Euphorbiaceae Eukaryota UNPD*
NPO2505 Pachycereus pringlei Species Cactaceae Eukaryota UNPD*
NPO1418 Boletinus paluster Species Gyrodontaceae Eukaryota UNPD*
NPO9375 Medium grandiflorum NA NA NA UNPD*
NPO9024 Aralidium pinnatifidum Species Torricelliaceae Eukaryota UNPD*
NPO13798 Cheilanthes marantae Species Pteridaceae Eukaryota UNPD*
NPO3576 Bersama swinnyi Species Melianthaceae Eukaryota UNPD*
NPO12577 Pinus glauca Species Pinaceae Eukaryota UNPD*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT2 Others Unspecified Ratio = 2.1 25819098
NPT2 Others Unspecified Ratio = 3.3 25819098
NPT2 Others Unspecified Ratio = 1.5 25819098
NPT2 Others Unspecified Ratio = 6.3 25819098
NPT178 Individual Protein Protein-tyrosine phosphatase 1B Homo sapiens IC50 = 19180 nM 25819098
NPT178 Individual Protein Protein-tyrosine phosphatase 1B Homo sapiens Ki = 12940 nM 25819098
NPT178 Individual Protein Protein-tyrosine phosphatase 1B Homo sapiens Inhibition = 93.8 % 25819098
NPT206 Individual Protein Protein-tyrosine phosphatase 2C Homo sapiens Inhibition = 44.4 % 25819098
NPT205 Individual Protein Protein-tyrosine phosphatase 1C Homo sapiens Inhibition = 28.7 % 25819098
NPT1211 Individual Protein Dual specificity protein phosphatase 3 Homo sapiens Inhibition = 61.4 % 25819098
NPT1210 Individual Protein T-cell protein-tyrosine phosphatase Homo sapiens Inhibition = 15 % 25819098

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC295898 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.886 High Similarity NPC174758
0.8593 High Similarity NPC274982
0.8571 High Similarity NPC174672
0.8442 Intermediate Similarity NPC264176
0.8387 Intermediate Similarity NPC84478
0.8366 Intermediate Similarity NPC305984
0.8333 Intermediate Similarity NPC82548
0.8325 Intermediate Similarity NPC303658
0.8317 Intermediate Similarity NPC194740
0.823 Intermediate Similarity NPC471762
0.8155 Intermediate Similarity NPC128115
0.815 Intermediate Similarity NPC287208
0.8131 Intermediate Similarity NPC53144
0.8057 Intermediate Similarity NPC66777
0.8043 Intermediate Similarity NPC65080
0.8038 Intermediate Similarity NPC122436
0.802 Intermediate Similarity NPC469589
0.8 Intermediate Similarity NPC285558
0.7991 Intermediate Similarity NPC141053
0.798 Intermediate Similarity NPC329747
0.7941 Intermediate Similarity NPC146418
0.794 Intermediate Similarity NPC232727
0.7933 Intermediate Similarity NPC281094
0.7933 Intermediate Similarity NPC17565
0.7892 Intermediate Similarity NPC85273
0.7861 Intermediate Similarity NPC200836
0.7857 Intermediate Similarity NPC198673
0.7853 Intermediate Similarity NPC176127
0.783 Intermediate Similarity NPC21638
0.7805 Intermediate Similarity NPC167860
0.7805 Intermediate Similarity NPC123976
0.7798 Intermediate Similarity NPC235685
0.7794 Intermediate Similarity NPC475910
0.7789 Intermediate Similarity NPC72211
0.7789 Intermediate Similarity NPC168911
0.7788 Intermediate Similarity NPC148183
0.7788 Intermediate Similarity NPC152768
0.7783 Intermediate Similarity NPC65277
0.7778 Intermediate Similarity NPC471080
0.7778 Intermediate Similarity NPC469592
0.7773 Intermediate Similarity NPC99891
0.7768 Intermediate Similarity NPC26543
0.7763 Intermediate Similarity NPC474183
0.7763 Intermediate Similarity NPC101350
0.7757 Intermediate Similarity NPC157931
0.7731 Intermediate Similarity NPC260434
0.7729 Intermediate Similarity NPC472098
0.7725 Intermediate Similarity NPC323969
0.7717 Intermediate Similarity NPC184680
0.7714 Intermediate Similarity NPC473041
0.7705 Intermediate Similarity NPC26850
0.77 Intermediate Similarity NPC239954
0.7696 Intermediate Similarity NPC472111
0.7696 Intermediate Similarity NPC72980
0.7688 Intermediate Similarity NPC70259
0.7682 Intermediate Similarity NPC470784
0.7682 Intermediate Similarity NPC470785
0.7659 Intermediate Similarity NPC249583
0.7659 Intermediate Similarity NPC4687
0.765 Intermediate Similarity NPC243834
0.765 Intermediate Similarity NPC70956
0.7642 Intermediate Similarity NPC472099
0.7638 Intermediate Similarity NPC131017
0.7638 Intermediate Similarity NPC43787
0.7638 Intermediate Similarity NPC205934
0.7637 Intermediate Similarity NPC26872
0.7635 Intermediate Similarity NPC211813
0.763 Intermediate Similarity NPC469594
0.7606 Intermediate Similarity NPC60621
0.76 Intermediate Similarity NPC13880
0.7598 Intermediate Similarity NPC162484
0.7594 Intermediate Similarity NPC213530
0.7594 Intermediate Similarity NPC193267
0.7581 Intermediate Similarity NPC177404
0.7559 Intermediate Similarity NPC477533
0.7549 Intermediate Similarity NPC475112
0.7549 Intermediate Similarity NPC475085
0.7549 Intermediate Similarity NPC291535
0.7548 Intermediate Similarity NPC471304
0.7538 Intermediate Similarity NPC62069
0.7537 Intermediate Similarity NPC11017
0.7525 Intermediate Similarity NPC306376
0.7524 Intermediate Similarity NPC316181
0.7524 Intermediate Similarity NPC151781
0.7524 Intermediate Similarity NPC74562
0.7523 Intermediate Similarity NPC131486
0.7512 Intermediate Similarity NPC87413
0.7489 Intermediate Similarity NPC91868
0.7489 Intermediate Similarity NPC63971
0.7487 Intermediate Similarity NPC92111
0.7478 Intermediate Similarity NPC303374
0.7476 Intermediate Similarity NPC308137
0.7476 Intermediate Similarity NPC310211
0.7475 Intermediate Similarity NPC296527
0.7475 Intermediate Similarity NPC267928
0.7464 Intermediate Similarity NPC470020
0.7462 Intermediate Similarity NPC204385
0.7453 Intermediate Similarity NPC170114
0.7452 Intermediate Similarity NPC470931
0.7451 Intermediate Similarity NPC329793
0.7451 Intermediate Similarity NPC176538
0.7451 Intermediate Similarity NPC121772
0.7448 Intermediate Similarity NPC312872
0.7442 Intermediate Similarity NPC198503
0.744 Intermediate Similarity NPC476106
0.7438 Intermediate Similarity NPC212213
0.7437 Intermediate Similarity NPC76748
0.7431 Intermediate Similarity NPC478078
0.7431 Intermediate Similarity NPC257851
0.7427 Intermediate Similarity NPC475774
0.7427 Intermediate Similarity NPC223427
0.7419 Intermediate Similarity NPC473449
0.7418 Intermediate Similarity NPC169402
0.7416 Intermediate Similarity NPC201697
0.7413 Intermediate Similarity NPC307963
0.7407 Intermediate Similarity NPC220851
0.7406 Intermediate Similarity NPC116238
0.7406 Intermediate Similarity NPC470549
0.7391 Intermediate Similarity NPC16452
0.7391 Intermediate Similarity NPC476581
0.7391 Intermediate Similarity NPC36229
0.7381 Intermediate Similarity NPC11464
0.7379 Intermediate Similarity NPC199277
0.7379 Intermediate Similarity NPC135887
0.7371 Intermediate Similarity NPC14325
0.7371 Intermediate Similarity NPC28848
0.7366 Intermediate Similarity NPC234197
0.7366 Intermediate Similarity NPC315957
0.7366 Intermediate Similarity NPC477019
0.736 Intermediate Similarity NPC258480
0.7359 Intermediate Similarity NPC244543
0.7349 Intermediate Similarity NPC298436
0.7347 Intermediate Similarity NPC206201
0.734 Intermediate Similarity NPC251090
0.7337 Intermediate Similarity NPC46580
0.733 Intermediate Similarity NPC267423
0.733 Intermediate Similarity NPC476044
0.7321 Intermediate Similarity NPC193777
0.7321 Intermediate Similarity NPC53344
0.7321 Intermediate Similarity NPC472061
0.732 Intermediate Similarity NPC288943
0.7317 Intermediate Similarity NPC476582
0.7317 Intermediate Similarity NPC4071
0.7317 Intermediate Similarity NPC476578
0.7315 Intermediate Similarity NPC150239
0.7311 Intermediate Similarity NPC202768
0.7311 Intermediate Similarity NPC296482
0.7311 Intermediate Similarity NPC53069
0.7311 Intermediate Similarity NPC316981
0.7309 Intermediate Similarity NPC253675
0.7308 Intermediate Similarity NPC470930
0.7302 Intermediate Similarity NPC46561
0.7302 Intermediate Similarity NPC96321
0.7302 Intermediate Similarity NPC247803
0.7294 Intermediate Similarity NPC322482
0.7286 Intermediate Similarity NPC39679
0.7286 Intermediate Similarity NPC66210
0.7282 Intermediate Similarity NPC19872
0.7282 Intermediate Similarity NPC283152
0.7281 Intermediate Similarity NPC310118
0.7277 Intermediate Similarity NPC133140
0.7277 Intermediate Similarity NPC195268
0.7277 Intermediate Similarity NPC162530
0.7277 Intermediate Similarity NPC236668
0.7273 Intermediate Similarity NPC473185
0.7269 Intermediate Similarity NPC208084
0.7269 Intermediate Similarity NPC288987
0.7265 Intermediate Similarity NPC473105
0.7265 Intermediate Similarity NPC329631
0.7264 Intermediate Similarity NPC174629
0.726 Intermediate Similarity NPC245816
0.726 Intermediate Similarity NPC476138
0.7257 Intermediate Similarity NPC41501
0.7256 Intermediate Similarity NPC473513
0.7252 Intermediate Similarity NPC475253
0.725 Intermediate Similarity NPC66083
0.7246 Intermediate Similarity NPC470586
0.7246 Intermediate Similarity NPC31930
0.7243 Intermediate Similarity NPC146976
0.724 Intermediate Similarity NPC311906
0.7238 Intermediate Similarity NPC270918
0.7238 Intermediate Similarity NPC313189
0.7235 Intermediate Similarity NPC174760
0.7233 Intermediate Similarity NPC287437
0.723 Intermediate Similarity NPC96405
0.723 Intermediate Similarity NPC171409
0.723 Intermediate Similarity NPC94157
0.723 Intermediate Similarity NPC48353
0.7222 Intermediate Similarity NPC173080
0.7217 Intermediate Similarity NPC269367
0.7209 Intermediate Similarity NPC330009
0.7202 Intermediate Similarity NPC477532
0.72 Intermediate Similarity NPC311858
0.7198 Intermediate Similarity NPC133609
0.7195 Intermediate Similarity NPC74575
0.719 Intermediate Similarity NPC300156
0.719 Intermediate Similarity NPC45190
0.719 Intermediate Similarity NPC475841
0.719 Intermediate Similarity NPC474145
0.7188 Intermediate Similarity NPC172222

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC295898 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.797 Intermediate Similarity NPD5658 Approved
0.7936 Intermediate Similarity NPD6790 Phase 1
0.7908 Intermediate Similarity NPD4418 Discontinued
0.784 Intermediate Similarity NPD3259 Approved
0.7767 Intermediate Similarity NPD6567 Clinical (unspecified phase)
0.7727 Intermediate Similarity NPD7025 Clinical (unspecified phase)
0.7727 Intermediate Similarity NPD6861 Clinical (unspecified phase)
0.7685 Intermediate Similarity NPD4952 Phase 3
0.7653 Intermediate Similarity NPD6824 Clinical (unspecified phase)
0.7617 Intermediate Similarity NPD4203 Approved
0.7617 Intermediate Similarity NPD4204 Approved
0.7588 Intermediate Similarity NPD1304 Clinical (unspecified phase)
0.758 Intermediate Similarity NPD4373 Phase 2
0.7573 Intermediate Similarity NPD7453 Approved
0.7573 Intermediate Similarity NPD7452 Approved
0.7573 Intermediate Similarity NPD7222 Phase 2
0.7571 Intermediate Similarity NPD4897 Phase 2
0.7561 Intermediate Similarity NPD4795 Phase 2
0.7559 Intermediate Similarity NPD6242 Discontinued
0.7558 Intermediate Similarity NPD7710 Clinical (unspecified phase)
0.7534 Intermediate Similarity NPD4885 Approved
0.7523 Intermediate Similarity NPD7589 Clinical (unspecified phase)
0.7488 Intermediate Similarity NPD4118 Clinical (unspecified phase)
0.7464 Intermediate Similarity NPD4900 Clinical (unspecified phase)
0.7455 Intermediate Similarity NPD7796 Approved
0.7455 Intermediate Similarity NPD7797 Approved
0.744 Intermediate Similarity NPD4901 Clinical (unspecified phase)
0.744 Intermediate Similarity NPD3003 Approved
0.7418 Intermediate Similarity NPD7823 Clinical (unspecified phase)
0.7413 Intermediate Similarity NPD1038 Approved
0.7411 Intermediate Similarity NPD6344 Clinical (unspecified phase)
0.7409 Intermediate Similarity NPD6962 Phase 2
0.7406 Intermediate Similarity NPD3257 Approved
0.7406 Intermediate Similarity NPD5293 Phase 2
0.7385 Intermediate Similarity NPD7426 Phase 1
0.7376 Intermediate Similarity NPD3324 Clinical (unspecified phase)
0.7366 Intermediate Similarity NPD1739 Approved
0.7366 Intermediate Similarity NPD1740 Approved
0.7361 Intermediate Similarity NPD5506 Approved
0.7361 Intermediate Similarity NPD5507 Approved
0.7356 Intermediate Similarity NPD5601 Phase 2
0.7333 Intermediate Similarity NPD2921 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD3920 Phase 2
0.7317 Intermediate Similarity NPD1768 Approved
0.7316 Intermediate Similarity NPD2915 Discontinued
0.7311 Intermediate Similarity NPD3816 Phase 1
0.7311 Intermediate Similarity NPD3815 Phase 1
0.7308 Intermediate Similarity NPD3397 Phase 2
0.7302 Intermediate Similarity NPD5632 Approved
0.7286 Intermediate Similarity NPD2916 Discontinued
0.7285 Intermediate Similarity NPD5801 Clinical (unspecified phase)
0.7277 Intermediate Similarity NPD3922 Approved
0.7277 Intermediate Similarity NPD4372 Phase 1
0.7277 Intermediate Similarity NPD3921 Approved
0.7277 Intermediate Similarity NPD3923 Approved
0.7277 Intermediate Similarity NPD3924 Approved
0.7273 Intermediate Similarity NPD7268 Clinical (unspecified phase)
0.7273 Intermediate Similarity NPD5530 Phase 1
0.7273 Intermediate Similarity NPD7994 Phase 2
0.7269 Intermediate Similarity NPD3258 Approved
0.7268 Intermediate Similarity NPD4987 Clinical (unspecified phase)
0.7265 Intermediate Similarity NPD6741 Clinical (unspecified phase)
0.726 Intermediate Similarity NPD6247 Clinical (unspecified phase)
0.7257 Intermediate Similarity NPD8016 Phase 3
0.7257 Intermediate Similarity NPD8017 Clinical (unspecified phase)
0.7248 Intermediate Similarity NPD2285 Clinical (unspecified phase)
0.7243 Intermediate Similarity NPD5903 Approved
0.7243 Intermediate Similarity NPD5902 Approved
0.7236 Intermediate Similarity NPD4889 Approved
0.7225 Intermediate Similarity NPD3946 Clinical (unspecified phase)
0.72 Intermediate Similarity NPD5444 Phase 1
0.7192 Intermediate Similarity NPD6569 Phase 2
0.7189 Intermediate Similarity NPD7194 Discontinued
0.7177 Intermediate Similarity NPD5513 Phase 2
0.7172 Intermediate Similarity NPD3386 Phase 2
0.7171 Intermediate Similarity NPD6550 Discontinued
0.7171 Intermediate Similarity NPD5512 Phase 3
0.7168 Intermediate Similarity NPD4368 Phase 2
0.7162 Intermediate Similarity NPD5559 Phase 2
0.7156 Intermediate Similarity NPD1392 Approved
0.7156 Intermediate Similarity NPD7180 Phase 3
0.7155 Intermediate Similarity NPD5482 Discontinued
0.715 Intermediate Similarity NPD6872 Clinical (unspecified phase)
0.7143 Intermediate Similarity NPD6568 Discontinued
0.7143 Intermediate Similarity NPD8405 Clinical (unspecified phase)
0.7137 Intermediate Similarity NPD4926 Clinical (unspecified phase)
0.7129 Intermediate Similarity NPD4334 Discontinued
0.7124 Intermediate Similarity NPD7853 Phase 2
0.7122 Intermediate Similarity NPD3810 Clinical (unspecified phase)
0.7118 Intermediate Similarity NPD6716 Phase 1
0.7116 Intermediate Similarity NPD3945 Discontinued
0.7109 Intermediate Similarity NPD8403 Phase 1
0.71 Intermediate Similarity NPD8359 Phase 2
0.7085 Intermediate Similarity NPD7414 Clinical (unspecified phase)
0.7083 Intermediate Similarity NPD5417 Clinical (unspecified phase)
0.7083 Intermediate Similarity NPD6140 Clinical (unspecified phase)
0.7082 Intermediate Similarity NPD6525 Clinical (unspecified phase)
0.708 Intermediate Similarity NPD6963 Approved
0.708 Intermediate Similarity NPD6964 Approved
0.7079 Intermediate Similarity NPD6393 Clinical (unspecified phase)
0.7078 Intermediate Similarity NPD5930 Phase 3
0.7077 Intermediate Similarity NPD1078 Clinical (unspecified phase)
0.7076 Intermediate Similarity NPD6961 Discontinued
0.7073 Intermediate Similarity NPD802 Phase 2
0.707 Intermediate Similarity NPD5866 Approved
0.7064 Intermediate Similarity NPD6985 Discontinued
0.7064 Intermediate Similarity NPD8463 Approved
0.7059 Intermediate Similarity NPD7547 Clinical (unspecified phase)
0.7059 Intermediate Similarity NPD3785 Clinical (unspecified phase)
0.7056 Intermediate Similarity NPD5483 Clinical (unspecified phase)
0.7056 Intermediate Similarity NPD5104 Approved
0.7053 Intermediate Similarity NPD6769 Clinical (unspecified phase)
0.7051 Intermediate Similarity NPD2433 Clinical (unspecified phase)
0.7044 Intermediate Similarity NPD6965 Clinical (unspecified phase)
0.704 Intermediate Similarity NPD4328 Approved
0.7039 Intermediate Similarity NPD6590 Discontinued
0.7039 Intermediate Similarity NPD4558 Phase 2
0.7039 Intermediate Similarity NPD3396 Approved
0.7039 Intermediate Similarity NPD3395 Approved
0.7033 Intermediate Similarity NPD4396 Clinical (unspecified phase)
0.7032 Intermediate Similarity NPD3763 Approved
0.703 Intermediate Similarity NPD5256 Discontinued
0.7028 Intermediate Similarity NPD7174 Clinical (unspecified phase)
0.7028 Intermediate Similarity NPD3507 Phase 2
0.7027 Intermediate Similarity NPD6246 Approved
0.7027 Intermediate Similarity NPD7719 Discontinued
0.7026 Intermediate Similarity NPD4724 Clinical (unspecified phase)
0.7022 Intermediate Similarity NPD7284 Clinical (unspecified phase)
0.7015 Intermediate Similarity NPD5083 Clinical (unspecified phase)
0.7014 Intermediate Similarity NPD6991 Approved
0.7 Intermediate Similarity NPD5850 Phase 3
0.7 Intermediate Similarity NPD7417 Discontinued
0.7 Intermediate Similarity NPD5070 Clinical (unspecified phase)
0.6995 Remote Similarity NPD2383 Phase 1
0.6991 Remote Similarity NPD7069 Discontinued
0.6991 Remote Similarity NPD7031 Phase 1
0.699 Remote Similarity NPD5575 Clinical (unspecified phase)
0.6987 Remote Similarity NPD7729 Clinical (unspecified phase)
0.6986 Remote Similarity NPD3825 Phase 3
0.6986 Remote Similarity NPD3354 Phase 2
0.6986 Remote Similarity NPD5948 Phase 2
0.6981 Remote Similarity NPD4036 Approved
0.6981 Remote Similarity NPD4039 Approved
0.6981 Remote Similarity NPD4033 Approved
0.6981 Remote Similarity NPD4035 Approved
0.6981 Remote Similarity NPD4037 Approved
0.6981 Remote Similarity NPD4122 Approved
0.6981 Remote Similarity NPD32 Approved
0.6981 Remote Similarity NPD31 Approved
0.6981 Remote Similarity NPD4038 Approved
0.6981 Remote Similarity NPD4034 Approved
0.6978 Remote Similarity NPD5479 Discontinued
0.6975 Remote Similarity NPD8091 Phase 3
0.6972 Remote Similarity NPD5612 Discontinued
0.6971 Remote Similarity NPD6206 Phase 1
0.697 Remote Similarity NPD6517 Phase 3
0.6966 Remote Similarity NPD8102 Discontinued
0.6964 Remote Similarity NPD4845 Discontinued
0.6963 Remote Similarity NPD2189 Approved
0.6963 Remote Similarity NPD2187 Approved
0.696 Remote Similarity NPD5040 Clinical (unspecified phase)
0.696 Remote Similarity NPD7558 Phase 2
0.6951 Remote Similarity NPD4132 Clinical (unspecified phase)
0.6948 Remote Similarity NPD6245 Phase 2
0.6947 Remote Similarity NPD1867 Approved
0.6946 Remote Similarity NPD7955 Approved
0.6946 Remote Similarity NPD7956 Approved
0.6944 Remote Similarity NPD3570 Phase 2
0.6943 Remote Similarity NPD4958 Clinical (unspecified phase)
0.6942 Remote Similarity NPD4315 Phase 2
0.6941 Remote Similarity NPD3326 Clinical (unspecified phase)
0.6938 Remote Similarity NPD6261 Phase 3
0.6937 Remote Similarity NPD6209 Approved
0.6935 Remote Similarity NPD3504 Approved
0.6935 Remote Similarity NPD3503 Approved
0.6923 Remote Similarity NPD3478 Clinical (unspecified phase)
0.6923 Remote Similarity NPD3477 Phase 2
0.692 Remote Similarity NPD7676 Clinical (unspecified phase)
0.692 Remote Similarity NPD7674 Phase 3
0.692 Remote Similarity NPD7675 Phase 3
0.6917 Remote Similarity NPD6228 Discontinued
0.6915 Remote Similarity NPD3037 Phase 1
0.6912 Remote Similarity NPD2749 Discontinued
0.6912 Remote Similarity NPD6141 Clinical (unspecified phase)
0.6909 Remote Similarity NPD4429 Discontinued
0.6905 Remote Similarity NPD6249 Phase 2
0.6905 Remote Similarity NPD6248 Phase 2
0.6905 Remote Similarity NPD4548 Discontinued
0.6905 Remote Similarity NPD2778 Approved
0.6901 Remote Similarity NPD3947 Discontinued
0.6898 Remote Similarity NPD3392 Approved
0.6898 Remote Similarity NPD1166 Clinical (unspecified phase)
0.6893 Remote Similarity NPD2334 Discontinued
0.6892 Remote Similarity NPD4923 Phase 1
0.689 Remote Similarity NPD6988 Phase 1
0.689 Remote Similarity NPD7948 Phase 1
0.6884 Remote Similarity NPD7671 Approved
0.6884 Remote Similarity NPD7672 Approved
0.6884 Remote Similarity NPD5863 Clinical (unspecified phase)
0.688 Remote Similarity NPD5488 Discontinued

Structure

External Identifiers

PubChem CID   10912909
ChEMBL   CHEMBL3400666
ZINC  

Physicochemical Properties

Molecular Weight:  280.08
ALogP:  -0.9738
MLogP:  2.67
XLogP:  2.151
# Rotatable Bonds:  3
Polar Surface Area:  51.54
# H-Bond Aceptor:  4
# H-Bond Donor:  0
# Rings:  4
# Heavy Atoms:  21

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Biological Activities  
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