Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO8601 | Petrosia volcano | Species | Petrosiidae | Eukaryota | UNPD* | |||
NPO11333 | Trapa japonica | Species | Lythraceae | Eukaryota | UNPD* | |||
NPO13042 | Diospyros abyssinica | Species | Ebenaceae | Eukaryota | UNPD* | |||
NPO12591 | Archaster typicus | Species | Archasteridae | Eukaryota | UNPD* | |||
NPO1326 | Cratystylis conocephala | Species | Asteraceae | Eukaryota | UNPD* | |||
NPO12819 | Clitocybe subilludens | Species | Tricholomataceae | Eukaryota | UNPD* | |||
NPO12367 | Diospyros elliptifolia | Species | Ebenaceae | Eukaryota | UNPD* | |||
NPO9361 | Aplophyllum villosum | NA | NA | NA | UNPD* | |||
NPO9783 | Mikania scandens | Species | Asteraceae | Eukaryota | UNPD* | |||
NPO5131 | Scorzonera hispanica | Species | Asteraceae | Eukaryota | UNPD* | |||
NPO13555 | Beaucarnea recurvata | Species | Asparagaceae | Eukaryota | UNPD* | |||
NPO9989 | Cotylelobium scabriusculum | Species | Dipterocarpaceae | Eukaryota | UNPD* | |||
NPO12233 | Diospyros peregrina | Species | Ebenaceae | Eukaryota | UNPD* | |||
NPO9553 | Phyllodium pulchellum | Species | Fabaceae | Eukaryota | UNPD* | |||
NPO7870 | Zanthoxylum piperitum | Species | Rutaceae | Eukaryota | UNPD* | |||
NPO6386 | Gutenbergia cordifolia | Species | Asteraceae | Eukaryota | UNPD* | |||
NPO22899 | Phaeotremella fagi | Species | Phaeotremellaceae | Eukaryota | UNPD* | |||
NPO4746 | Centaurea arenaria | Species | Asteraceae | Eukaryota | UNPD* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT1287 | Individual Protein | Cannabinoid CB2 receptor | Homo sapiens | Inhibition | = | 64 | % | 24175626 |
NPT5620 | Individual Protein | Relaxin-3 receptor 1 | Homo sapiens | Inhibition | = | -81 | % | 24175626 |
NPT2766 | Individual Protein | Prostanoid EP2 receptor | Homo sapiens | Inhibition | = | -52 | % | 24175626 |
NPT988 | Individual Protein | Histamine H4 receptor | Homo sapiens | Inhibition | = | -54 | % | 24175626 |
NPT5621 | Individual Protein | Follicle stimulating hormone receptor | Homo sapiens | Inhibition | = | 68 | % | 24175626 |
NPT5622 | Individual Protein | Prolactin-releasing peptide receptor | Homo sapiens | Inhibition | = | 52 | % | 24175626 |
NPT232 | Individual Protein | Cannabinoid CB1 receptor | Homo sapiens | Inhibition | = | 15 | % | 24175626 |
NPT1287 | Individual Protein | Cannabinoid CB2 receptor | Homo sapiens | Inhibition | = | 72 | % | 24175626 |
NPT5620 | Individual Protein | Relaxin-3 receptor 1 | Homo sapiens | Activity | = | 18 | % | 24175626 |
NPT2766 | Individual Protein | Prostanoid EP2 receptor | Homo sapiens | Activity | = | 7 | % | 24175626 |
NPT988 | Individual Protein | Histamine H4 receptor | Homo sapiens | Activity | = | 18 | % | 24175626 |
NPT5623 | Individual Protein | Probable G-protein coupled receptor 151 | Homo sapiens | Activity | = | 76 | % | 24175626 |
NPT5624 | Individual Protein | Probable G-protein coupled receptor 132 | Homo sapiens | Activity | = | 61 | % | 24175626 |
NPT4120 | Individual Protein | G-protein coupled receptor 55 | Homo sapiens | Activity | = | 67 | % | 24175626 |
NPT5621 | Individual Protein | Follicle stimulating hormone receptor | Homo sapiens | Activity | = | 5 | % | 24175626 |
NPT5622 | Individual Protein | Prolactin-releasing peptide receptor | Homo sapiens | Activity | = | 5 | % | 24175626 |
NPT232 | Individual Protein | Cannabinoid CB1 receptor | Homo sapiens | Activity | = | 5 | % | 24175626 |
NPT1287 | Individual Protein | Cannabinoid CB2 receptor | Homo sapiens | EC50 | = | 41.7 | nM | 24175626 |
NPT2 | Others | Unspecified | Ratio IC50 | = | 0.15 | 24175626 | ||
NPT1287 | Individual Protein | Cannabinoid CB2 receptor | Homo sapiens | Inhibition | = | 57 | % | 24175626 |
NPT1287 | Individual Protein | Cannabinoid CB2 receptor | Homo sapiens | IC50 | = | 664 | nM | 24175626 |
NPT232 | Individual Protein | Cannabinoid CB1 receptor | Homo sapiens | Inhibition | = | 37 | % | 24175626 |
NPT232 | Individual Protein | Cannabinoid CB1 receptor | Homo sapiens | IC50 | = | 100 | nM | 24175626 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC267340 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
1.0 | High Similarity | NPC243539 |
1.0 | High Similarity | NPC145032 |
1.0 | High Similarity | NPC54542 |
1.0 | High Similarity | NPC304223 |
0.9787 | High Similarity | NPC267692 |
0.9787 | High Similarity | NPC307435 |
0.9592 | High Similarity | NPC119655 |
0.9592 | High Similarity | NPC303672 |
0.94 | High Similarity | NPC56028 |
0.94 | High Similarity | NPC167759 |
0.94 | High Similarity | NPC305288 |
0.94 | High Similarity | NPC163912 |
0.9388 | High Similarity | NPC195986 |
0.9216 | High Similarity | NPC273023 |
0.9216 | High Similarity | NPC471991 |
0.9216 | High Similarity | NPC297020 |
0.9216 | High Similarity | NPC471992 |
0.9038 | High Similarity | NPC261158 |
0.9038 | High Similarity | NPC24216 |
0.9038 | High Similarity | NPC104138 |
0.9038 | High Similarity | NPC306420 |
0.9038 | High Similarity | NPC477049 |
0.902 | High Similarity | NPC44193 |
0.902 | High Similarity | NPC246519 |
0.902 | High Similarity | NPC14234 |
0.902 | High Similarity | NPC132669 |
0.902 | High Similarity | NPC184014 |
0.902 | High Similarity | NPC123669 |
0.902 | High Similarity | NPC269800 |
0.8393 | Intermediate Similarity | NPC6795 |
0.8302 | Intermediate Similarity | NPC13011 |
0.8302 | Intermediate Similarity | NPC124382 |
0.8214 | Intermediate Similarity | NPC312826 |
0.82 | Intermediate Similarity | NPC91044 |
0.8182 | Intermediate Similarity | NPC245650 |
0.7797 | Intermediate Similarity | NPC471023 |
0.7705 | Intermediate Similarity | NPC187315 |
0.7667 | Intermediate Similarity | NPC253468 |
0.7667 | Intermediate Similarity | NPC235311 |
0.7586 | Intermediate Similarity | NPC74617 |
0.7586 | Intermediate Similarity | NPC150505 |
0.7541 | Intermediate Similarity | NPC477525 |
0.75 | Intermediate Similarity | NPC77891 |
0.7419 | Intermediate Similarity | NPC315141 |
0.7419 | Intermediate Similarity | NPC129995 |
0.74 | Intermediate Similarity | NPC86121 |
0.74 | Intermediate Similarity | NPC470439 |
0.7368 | Intermediate Similarity | NPC4881 |
0.7333 | Intermediate Similarity | NPC324077 |
0.7167 | Intermediate Similarity | NPC309877 |
0.7167 | Intermediate Similarity | NPC130807 |
0.7077 | Intermediate Similarity | NPC471022 |
0.7049 | Intermediate Similarity | NPC273614 |
0.6833 | Remote Similarity | NPC210999 |
0.6792 | Remote Similarity | NPC299114 |
0.6774 | Remote Similarity | NPC29468 |
0.6765 | Remote Similarity | NPC314678 |
0.6667 | Remote Similarity | NPC182758 |
0.661 | Remote Similarity | NPC242930 |
0.6604 | Remote Similarity | NPC138935 |
0.6418 | Remote Similarity | NPC249713 |
0.629 | Remote Similarity | NPC325734 |
0.629 | Remote Similarity | NPC321030 |
0.6226 | Remote Similarity | NPC206906 |
0.619 | Remote Similarity | NPC329003 |
0.619 | Remote Similarity | NPC326524 |
0.619 | Remote Similarity | NPC325550 |
0.6184 | Remote Similarity | NPC14326 |
0.6102 | Remote Similarity | NPC208638 |
0.6087 | Remote Similarity | NPC103712 |
0.6087 | Remote Similarity | NPC45060 |
0.6087 | Remote Similarity | NPC280065 |
0.6087 | Remote Similarity | NPC291196 |
0.6071 | Remote Similarity | NPC180575 |
0.6038 | Remote Similarity | NPC269823 |
0.6 | Remote Similarity | NPC313911 |
0.6 | Remote Similarity | NPC314854 |
0.5962 | Remote Similarity | NPC15934 |
0.5962 | Remote Similarity | NPC182840 |
0.5962 | Remote Similarity | NPC29091 |
0.5962 | Remote Similarity | NPC103213 |
0.5962 | Remote Similarity | NPC255042 |
0.5932 | Remote Similarity | NPC261571 |
0.5926 | Remote Similarity | NPC213538 |
0.5926 | Remote Similarity | NPC256766 |
0.5909 | Remote Similarity | NPC477106 |
0.5909 | Remote Similarity | NPC316674 |
0.5849 | Remote Similarity | NPC56917 |
0.5849 | Remote Similarity | NPC145077 |
0.5833 | Remote Similarity | NPC188341 |
0.5833 | Remote Similarity | NPC49494 |
0.5818 | Remote Similarity | NPC116934 |
0.58 | Remote Similarity | NPC58957 |
0.5763 | Remote Similarity | NPC291437 |
0.5763 | Remote Similarity | NPC328784 |
0.5753 | Remote Similarity | NPC288086 |
0.575 | Remote Similarity | NPC3210 |
0.5676 | Remote Similarity | NPC476923 |
0.5667 | Remote Similarity | NPC71053 |
0.5667 | Remote Similarity | NPC59408 |
0.5667 | Remote Similarity | NPC43053 |
0.5636 | Remote Similarity | NPC68889 |
0.5636 | Remote Similarity | NPC51758 |
0.5636 | Remote Similarity | NPC209279 |
0.5636 | Remote Similarity | NPC304151 |
0.5636 | Remote Similarity | NPC88079 |
0.5636 | Remote Similarity | NPC108494 |
0.5636 | Remote Similarity | NPC180871 |
0.5636 | Remote Similarity | NPC67761 |
0.5636 | Remote Similarity | NPC194586 |
0.5614 | Remote Similarity | NPC160628 |
0.5614 | Remote Similarity | NPC269074 |
0.5614 | Remote Similarity | NPC140501 |
0.561 | Remote Similarity | NPC473031 |
0.56 | Remote Similarity | NPC250734 |
0.56 | Remote Similarity | NPC263266 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC267340 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
PubChem CID   | 5318518 |
ChEMBL   | CHEMBL3086844 |
ZINC   |
Molecular Weight:   | 273.21 |
ALogP:   | 3.4617 |
MLogP:   | 3.22 |
XLogP:   | 5.864 |
# Rotatable Bonds:   | 13 |
Polar Surface Area:   | 32.59 |
# H-Bond Aceptor:   | 2 |
# H-Bond Donor:   | 1 |
# Rings:   | 0 |
# Heavy Atoms:   | 20 |