Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO29515 | Laurus nobilis | Species | Lauraceae | Eukaryota | UNPD* | |||
NPO29105 | Meconopsis punicea | Species | Papaveraceae | Eukaryota | UNPD* | |||
NPO24627 | Chondromyces robustus | Species | Polyangiaceae | Bacteria | UNPD* | |||
NPO29118 | Euonymus alatus | Species | Celastraceae | Eukaryota | UNPD* | |||
NPO29212 | Tanaecium jaroba | Species | Bignoniaceae | Eukaryota | UNPD* | |||
NPO29303 | Salvia multicaulis | Species | Lamiaceae | Eukaryota | UNPD* | |||
NPO29323 | Glaucium leiocarpum | Species | Papaveraceae | Eukaryota | UNPD* | |||
NPO29050 | Lemnalia nitida | Species | Nephtheidae | Eukaryota | UNPD* | |||
NPO22397 | Equiseti hiemalis herba | NA | NA | NA | TCMSP* | |||
NPO20568 | Hyperici japonici herber | NA | NA | NA | TCMSP* | |||
NPO3330 | Capsellae herba | NA | NA | NA | TCMSP* | |||
NPO2997 | Aloe africana | Species | Xanthorrhoeaceae | Eukaryota | TM-MC* | |||
NPO11578 | Aloe vera | Species | Xanthorrhoeaceae | Eukaryota | TM-MC* | |||
NPO14763 | Aloe ferox | Species | Asphodelaceae | Eukaryota | TM-MC* | |||
NPO2837 | Aloe spicata | Species | Asphodelaceae | Eukaryota | TM-MC* | |||
NPO28574 | Oroxylum indicum | Species | Bignoniaceae | Eukaryota | TM-MC* | |||
NPO1493 | Hericium erinaceus | Species | Hericiaceae | Eukaryota | TCMID* | |||
NPO10084 | Equisetum hyemale | Species | Equisetaceae | Eukaryota | TCMID* | |||
NPO15462 | Angelica sinensis | Species | Apiaceae | Eukaryota | TCMID* | |||
NPO28876 | Narcissus cyclamineus | Species | Amaryllidaceae | Eukaryota | UNPD* | |||
NPO29391 | Papaver bracteatum | Species | Papaveraceae | Eukaryota | UNPD* | |||
NPO15462 | Angelica sinensis | Species | Apiaceae | Eukaryota | HerDing* | |||
NPO1797 | Homo sapiens | Species | Hominidae | Eukaryota | saliva | DOI[10.1007/s11306-015-0840-5] | ||
NPO1797 | Homo sapiens | Species | Hominidae | Eukaryota | urine |
PMID[24023812] |
||
NPO1797 | Homo sapiens | Species | Hominidae | Eukaryota | blood |
PMID[15996001] |
||
NPO1797 | Homo sapiens | Species | Hominidae | Eukaryota | cerebrospinal fluid |
PMID[18502700] |
||
NPO30744 | Equisetum hiemale | Species | Equisetaceae | Eukaryota | TCM_Taiwan* | |||
NPO30744 | Equisetum hiemale | Species | Equisetaceae | Eukaryota | HerDing* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT1722 | Individual Protein | Choline acetylase | Rattus norvegicus | Ki | = | 28000000 | nM | 4032433 |
NPT1722 | Individual Protein | Choline acetylase | Rattus norvegicus | Ki | = | 260000000 | nM | 4032433 |
NPT48 | Individual Protein | Lysine-specific demethylase 4D-like | Homo sapiens | Potency | = | 39810.7 | nM | PubChem BioAssay data set |
NPT109 | Individual Protein | Cytochrome P450 3A4 | Homo sapiens | Potency | = | 19952.6 | nM | PubChem BioAssay data set |
NPT533 | Protein-Protein Interaction | Runt-related transcription factor 1/Core-binding factor subunit beta | Homo sapiens | Potency | 25118.9 | nM | PubChem BioAssay data set | |
NPT72 | Individual Protein | Solute carrier organic anion transporter family member 1B3 | Homo sapiens | Inhibition | = | 102.71 | % | 23571415 |
NPT73 | Individual Protein | Solute carrier organic anion transporter family member 1B1 | Homo sapiens | Inhibition | = | 115.06 | % | 23571415 |
NPT2 | Others | Unspecified | Potency | 1995.3 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 4466.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 4327.7 | nM | PubChem BioAssay data set | ||
NPT2607 | Individual Protein | Cereblon isoform 4 | Magnetospirillum gryphiswaldense | IC50 | = | 10000000 | nM | 26730808 |
NPT2608 | Individual Protein | Protein cereblon | Homo sapiens | IC50 | = | 181000000 | nM | 26730808 |
NPT2 | Others | Unspecified | IC50 | = | 361000000 | nM | 26730808 | |
NPT2 | Others | Unspecified | IC50 | = | 737000000 | nM | 26730808 | |
NPT2607 | Individual Protein | Cereblon isoform 4 | Magnetospirillum gryphiswaldense | Ki | = | 5690000 | nM | 26730808 |
NPT2608 | Individual Protein | Protein cereblon | Homo sapiens | Ki | = | 137490000 | nM | 26730808 |
NPT2 | Others | Unspecified | Ki | = | 312200000 | nM | 26730808 | |
NPT2 | Others | Unspecified | Ki | = | 664460000 | nM | 26730808 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC256853 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC256853 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
PubChem CID   | 6213 |
ChEMBL   | CHEMBL25028 |
ZINC   |
Molecular Weight:   | 94.01 |
ALogP:   | -0.2206 |
MLogP:   | 1.35 |
XLogP:   | 0.09 |
# Rotatable Bonds:   | 2 |
Polar Surface Area:   | 42.52 |
# H-Bond Aceptor:   | 2 |
# H-Bond Donor:   | 0 |
# Rings:   | 0 |
# Heavy Atoms:   | 5 |