Natural Product: NPC184964

Natural Product ID:  NPC184964
Common Name:   1H-Indol-5-Ol
IUPAC Name:   1H-indol-5-ol
Synonyms:   5-Hydroxyindole
Molecular Formula:   C8H7NO
Standard InCHIKey:  LMIQERWZRIFWNZ-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
Canonical SMILES:  Oc1ccc2c(c1)cc[nH]2
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO1797 Homo sapiens Species Hominidae Eukaryota blood PMID[21784895]
NPO1797 Homo sapiens Species Hominidae Eukaryota Faeces PMID[24029555]
NPO31073 Ligusticum chuanxiong Species Apiaceae Eukaryota TCM_Taiwan*
NPO10515 Angelicae sinensis radix NA NA NA TCMSP*
NPO22033 Cnidium officinale Species Apiaceae Eukaryota TM-MC*
NPO18951 Ligusticum sinense Species Apiaceae Eukaryota TM-MC*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT410 Individual Protein Neuronal acetylcholine receptor protein alpha-7 subunit Homo sapiens EC50 = 1000000 nM 18198823
NPT2520 Individual Protein Leukotriene A4 hydrolase Homo sapiens IC50 > 1000000 nM 19618939
NPT2520 Individual Protein Leukotriene A4 hydrolase Homo sapiens IC50 > 2000000 nM 19618939
NPT319 Cell Line B16 Mus musculus Activity = 100 % 19524439
NPT319 Cell Line B16 Mus musculus IC50 = 13000 nM 19524439
NPT741 Individual Protein Tyrosinase Homo sapiens Activity = 54 % 19524439
NPT2739 Individual Protein Tyrosinase Mus musculus Activity = 62 % 19524439
NPT2739 Individual Protein Tyrosinase Mus musculus IC50 = 68000 nM 19524439
NPT2264 Protein Family Heat shock protein HSP90 Homo sapiens IC50 > 50000 nM PubChem BioAssay data set
NPT2 Others Unspecified IC50 = 2230 nM PubChem BioAssay data set
NPT792 Individual Protein Arachidonate 15-lipoxygenase Homo sapiens Potency = 10000 nM PubChem BioAssay data set
NPT45 Individual Protein Ubiquitin carboxyl-terminal hydrolase 2 Homo sapiens Potency = 7943.3 nM PubChem BioAssay data set
NPT60 Individual Protein Lysosomal alpha-glucosidase Homo sapiens Potency = 14125.4 nM PubChem BioAssay data set
NPT1416 Individual Protein Neuropeptide S receptor Homo sapiens Potency = 5011.9 nM PubChem BioAssay data set
NPT4 Individual Protein Large T antigen Simian virus 40 IC50 80220 nM PubChem BioAssay data set
NPT64 Individual Protein ATPase family AAA domain-containing protein 5 Homo sapiens Potency 4466.8 nM PubChem BioAssay data set
NPT6 Organism Plasmodium falciparum Plasmodium falciparum Potency 18526 nM PubChem BioAssay data set
NPT66 Individual Protein Acetylcholinesterase Electrophorus electricus Inhibition = 7.33 % 22425563
NPT10 Individual Protein Geminin Homo sapiens Potency 8199.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 16360.1 nM PubChem BioAssay data set
NPT2 Others Unspecified Inhibition = 79.8 % 23777828
NPT2 Others Unspecified Inhibition > 90.1 % 24411196
NPT2 Others Unspecified Inhibition = 79.8 % 24411196
NPT1 Others Radical scavenging activity Activity = 2.6 10'3/M/s 10.1039/C2MD20287E
NPT5045 Individual Protein DNA repair protein RAD51 homolog 1 Homo sapiens Kd = 2100000 nM 25971770

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC184964 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9753 High Similarity NPC220765
0.9693 High Similarity NPC204717
0.9634 High Similarity NPC314002
0.9576 High Similarity NPC171171
0.9294 High Similarity NPC99666
0.9186 High Similarity NPC326634
0.9152 High Similarity NPC96890
0.9133 High Similarity NPC222018
0.908 High Similarity NPC77555
0.908 High Similarity NPC156704
0.9059 High Similarity NPC46580
0.8927 High Similarity NPC45459
0.8927 High Similarity NPC213308
0.8927 High Similarity NPC315491
0.8914 High Similarity NPC251090
0.8908 High Similarity NPC307963
0.8895 High Similarity NPC296527
0.8844 High Similarity NPC76748
0.8793 High Similarity NPC92111
0.8786 High Similarity NPC32771
0.8712 High Similarity NPC131718
0.8647 High Similarity NPC88363
0.8634 High Similarity NPC88008
0.8626 High Similarity NPC475070
0.8606 High Similarity NPC102423
0.8596 High Similarity NPC242209
0.8587 High Similarity NPC171787
0.8538 High Similarity NPC42979
0.8529 High Similarity NPC224764
0.8427 Intermediate Similarity NPC324149
0.8424 Intermediate Similarity NPC230869
0.8404 Intermediate Similarity NPC219087
0.8402 Intermediate Similarity NPC314940
0.8402 Intermediate Similarity NPC473764
0.8398 Intermediate Similarity NPC192315
0.8396 Intermediate Similarity NPC5145
0.836 Intermediate Similarity NPC266931
0.836 Intermediate Similarity NPC477610
0.8352 Intermediate Similarity NPC476167
0.8324 Intermediate Similarity NPC72980
0.8307 Intermediate Similarity NPC316981
0.8306 Intermediate Similarity NPC176538
0.8304 Intermediate Similarity NPC313791
0.8304 Intermediate Similarity NPC474409
0.8278 Intermediate Similarity NPC106937
0.8258 Intermediate Similarity NPC128751
0.8258 Intermediate Similarity NPC246700
0.8254 Intermediate Similarity NPC246518
0.8232 Intermediate Similarity NPC276517
0.8212 Intermediate Similarity NPC106833
0.8212 Intermediate Similarity NPC469497
0.8187 Intermediate Similarity NPC477609
0.8182 Intermediate Similarity NPC176127
0.8155 Intermediate Similarity NPC279918
0.8148 Intermediate Similarity NPC159856
0.8144 Intermediate Similarity NPC74360
0.814 Intermediate Similarity NPC252590
0.8135 Intermediate Similarity NPC304926
0.8135 Intermediate Similarity NPC476041
0.8108 Intermediate Similarity NPC249040
0.8107 Intermediate Similarity NPC282231
0.8103 Intermediate Similarity NPC276657
0.8095 Intermediate Similarity NPC476465
0.8087 Intermediate Similarity NPC13880
0.8075 Intermediate Similarity NPC476098
0.8072 Intermediate Similarity NPC469765
0.8072 Intermediate Similarity NPC469760
0.8072 Intermediate Similarity NPC469786
0.8072 Intermediate Similarity NPC73952
0.8072 Intermediate Similarity NPC25008
0.8072 Intermediate Similarity NPC469763
0.8072 Intermediate Similarity NPC259644
0.8042 Intermediate Similarity NPC183777
0.8024 Intermediate Similarity NPC80597
0.8024 Intermediate Similarity NPC212376
0.8024 Intermediate Similarity NPC70922
0.8024 Intermediate Similarity NPC75540
0.8024 Intermediate Similarity NPC211572
0.8021 Intermediate Similarity NPC211813
0.799 Intermediate Similarity NPC142901
0.7989 Intermediate Similarity NPC477113
0.798 Intermediate Similarity NPC130570
0.7978 Intermediate Similarity NPC212535
0.7976 Intermediate Similarity NPC469785
0.7965 Intermediate Similarity NPC49954
0.7965 Intermediate Similarity NPC54988
0.7965 Intermediate Similarity NPC160105
0.7965 Intermediate Similarity NPC474561
0.7958 Intermediate Similarity NPC476116
0.7953 Intermediate Similarity NPC311276
0.7952 Intermediate Similarity NPC105818
0.7952 Intermediate Similarity NPC24678
0.7947 Intermediate Similarity NPC270918
0.7946 Intermediate Similarity NPC153042
0.7937 Intermediate Similarity NPC470500
0.7929 Intermediate Similarity NPC469762
0.7927 Intermediate Similarity NPC128084
0.7927 Intermediate Similarity NPC314372
0.7919 Intermediate Similarity NPC78020
0.7919 Intermediate Similarity NPC63751
0.7914 Intermediate Similarity NPC121772
0.7914 Intermediate Similarity NPC190296
0.7889 Intermediate Similarity NPC94943
0.7877 Intermediate Similarity NPC48938
0.7876 Intermediate Similarity NPC208284
0.787 Intermediate Similarity NPC141353
0.7853 Intermediate Similarity NPC111275
0.7853 Intermediate Similarity NPC60553
0.785 Intermediate Similarity NPC245348
0.7848 Intermediate Similarity NPC82295
0.7833 Intermediate Similarity NPC190007
0.7822 Intermediate Similarity NPC477607
0.7822 Intermediate Similarity NPC477608
0.7819 Intermediate Similarity NPC315957
0.7817 Intermediate Similarity NPC264285
0.7814 Intermediate Similarity NPC83111
0.7812 Intermediate Similarity NPC477111
0.7802 Intermediate Similarity NPC278434
0.7801 Intermediate Similarity NPC476121
0.7801 Intermediate Similarity NPC476124
0.779 Intermediate Similarity NPC163421
0.779 Intermediate Similarity NPC188387
0.7784 Intermediate Similarity NPC314603
0.7784 Intermediate Similarity NPC329541
0.7778 Intermediate Similarity NPC232727
0.7772 Intermediate Similarity NPC80596
0.7772 Intermediate Similarity NPC6215
0.7754 Intermediate Similarity NPC90229
0.7747 Intermediate Similarity NPC315555
0.7746 Intermediate Similarity NPC40779
0.7746 Intermediate Similarity NPC194640
0.774 Intermediate Similarity NPC203468
0.774 Intermediate Similarity NPC110500
0.774 Intermediate Similarity NPC149155
0.7737 Intermediate Similarity NPC135887
0.7737 Intermediate Similarity NPC199277
0.7732 Intermediate Similarity NPC11464
0.7723 Intermediate Similarity NPC60006
0.7722 Intermediate Similarity NPC71037
0.7716 Intermediate Similarity NPC477110
0.7714 Intermediate Similarity NPC201700
0.7709 Intermediate Similarity NPC55772
0.7707 Intermediate Similarity NPC207686
0.7697 Intermediate Similarity NPC267885
0.7696 Intermediate Similarity NPC245816
0.7696 Intermediate Similarity NPC223427
0.7696 Intermediate Similarity NPC476138
0.7688 Intermediate Similarity NPC213530
0.7688 Intermediate Similarity NPC193267
0.768 Intermediate Similarity NPC469358
0.7674 Intermediate Similarity NPC92796
0.7674 Intermediate Similarity NPC135141
0.7656 Intermediate Similarity NPC285558
0.7654 Intermediate Similarity NPC261195
0.7654 Intermediate Similarity NPC96102
0.7654 Intermediate Similarity NPC29886
0.7654 Intermediate Similarity NPC151939
0.7654 Intermediate Similarity NPC248454
0.7654 Intermediate Similarity NPC59269
0.7644 Intermediate Similarity NPC470678
0.7641 Intermediate Similarity NPC309845
0.7637 Intermediate Similarity NPC84478
0.7632 Intermediate Similarity NPC19872
0.7632 Intermediate Similarity NPC329793
0.7629 Intermediate Similarity NPC18348
0.7626 Intermediate Similarity NPC470799
0.7626 Intermediate Similarity NPC8022
0.7619 Intermediate Similarity NPC471957
0.7619 Intermediate Similarity NPC306376
0.7612 Intermediate Similarity NPC473317
0.7611 Intermediate Similarity NPC126709
0.7611 Intermediate Similarity NPC248041
0.7611 Intermediate Similarity NPC283219
0.7607 Intermediate Similarity NPC84911
0.7607 Intermediate Similarity NPC105127
0.76 Intermediate Similarity NPC471178
0.7596 Intermediate Similarity NPC15102
0.7577 Intermediate Similarity NPC193777
0.7574 Intermediate Similarity NPC16352
0.7569 Intermediate Similarity NPC300688
0.756 Intermediate Similarity NPC15801
0.7553 Intermediate Similarity NPC131017
0.7538 Intermediate Similarity NPC469928
0.7528 Intermediate Similarity NPC470498
0.7527 Intermediate Similarity NPC233936
0.7527 Intermediate Similarity NPC154339
0.7527 Intermediate Similarity NPC95783
0.7515 Intermediate Similarity NPC110126
0.7515 Intermediate Similarity NPC73767
0.7513 Intermediate Similarity NPC200836
0.7513 Intermediate Similarity NPC53144
0.7513 Intermediate Similarity NPC475774
0.7512 Intermediate Similarity NPC295228
0.7512 Intermediate Similarity NPC477549
0.75 Intermediate Similarity NPC125597
0.75 Intermediate Similarity NPC469727
0.7487 Intermediate Similarity NPC470549
0.7487 Intermediate Similarity NPC128823
0.7487 Intermediate Similarity NPC321428
0.7486 Intermediate Similarity NPC163055

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC184964 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.924 High Similarity NPD5575 Clinical (unspecified phase)
0.8927 High Similarity NPD484 Approved
0.8908 High Similarity NPD1038 Approved
0.8693 High Similarity NPD1304 Clinical (unspecified phase)
0.8547 High Similarity NPD7948 Phase 1
0.8278 Intermediate Similarity NPD802 Phase 2
0.8272 Intermediate Similarity NPD5612 Discontinued
0.8272 Intermediate Similarity NPD6803 Clinical (unspecified phase)
0.8155 Intermediate Similarity NPD9705 Discontinued
0.8155 Intermediate Similarity NPD112 Approved
0.815 Intermediate Similarity NPD5065 Approved
0.815 Intermediate Similarity NPD9690 Approved
0.8095 Intermediate Similarity NPD2187 Approved
0.8095 Intermediate Similarity NPD2189 Approved
0.809 Intermediate Similarity NPD6344 Clinical (unspecified phase)
0.7979 Intermediate Similarity NPD1322 Clinical (unspecified phase)
0.7957 Intermediate Similarity NPD3825 Phase 3
0.7935 Intermediate Similarity NPD3324 Clinical (unspecified phase)
0.788 Intermediate Similarity NPD9695 Approved
0.7874 Intermediate Similarity NPD1325 Approved
0.7874 Intermediate Similarity NPD1326 Approved
0.7874 Intermediate Similarity NPD4184 Clinical (unspecified phase)
0.7853 Intermediate Similarity NPD1392 Approved
0.7819 Intermediate Similarity NPD1739 Approved
0.7819 Intermediate Similarity NPD1740 Approved
0.7778 Intermediate Similarity NPD4511 Phase 1
0.7744 Intermediate Similarity NPD1592 Phase 3
0.774 Intermediate Similarity NPD482 Approved
0.7727 Intermediate Similarity NPD8405 Clinical (unspecified phase)
0.7697 Intermediate Similarity NPD749 Clinical (unspecified phase)
0.7674 Intermediate Similarity NPD604 Clinical (unspecified phase)
0.7672 Intermediate Similarity NPD4118 Clinical (unspecified phase)
0.7657 Intermediate Similarity NPD425 Approved
0.7657 Intermediate Similarity NPD424 Approved
0.7656 Intermediate Similarity NPD4795 Phase 2
0.7654 Intermediate Similarity NPD198 Clinical (unspecified phase)
0.765 Intermediate Similarity NPD6242 Discontinued
0.7644 Intermediate Similarity NPD3928 Approved
0.7644 Intermediate Similarity NPD3931 Approved
0.7588 Intermediate Similarity NPD9706 Clinical (unspecified phase)
0.7582 Intermediate Similarity NPD2094 Phase 2
0.7582 Intermediate Similarity NPD2095 Phase 2
0.7582 Intermediate Similarity NPD2092 Phase 2
0.7579 Intermediate Similarity NPD3814 Phase 1
0.7569 Intermediate Similarity NPD6595 Phase 3
0.7541 Intermediate Similarity NPD2096 Phase 2
0.7541 Intermediate Similarity NPD2091 Phase 2
0.754 Intermediate Similarity NPD9689 Approved
0.7538 Intermediate Similarity NPD7112 Discontinued
0.7515 Intermediate Similarity NPD786 Approved
0.7513 Intermediate Similarity NPD949 Phase 1
0.7512 Intermediate Similarity NPD4845 Discontinued
0.75 Intermediate Similarity NPD926 Approved
0.75 Intermediate Similarity NPD925 Approved
0.7487 Intermediate Similarity NPD3930 Clinical (unspecified phase)
0.7487 Intermediate Similarity NPD1768 Approved
0.7475 Intermediate Similarity NPD3330 Phase 1
0.7463 Intermediate Similarity NPD7603 Discontinued
0.7447 Intermediate Similarity NPD3404 Approved
0.7443 Intermediate Similarity NPD5140 Approved
0.7443 Intermediate Similarity NPD5138 Approved
0.7436 Intermediate Similarity NPD3932 Clinical (unspecified phase)
0.7425 Intermediate Similarity NPD1722 Approved
0.7424 Intermediate Similarity NPD5067 Phase 2
0.7424 Intermediate Similarity NPD5066 Phase 2
0.7416 Intermediate Similarity NPD5040 Clinical (unspecified phase)
0.7416 Intermediate Similarity NPD5069 Clinical (unspecified phase)
0.7405 Intermediate Similarity NPD6610 Clinical (unspecified phase)
0.7396 Intermediate Similarity NPD8395 Approved
0.7396 Intermediate Similarity NPD2175 Phase 3
0.7396 Intermediate Similarity NPD2176 Approved
0.7396 Intermediate Similarity NPD2177 Approved
0.7396 Intermediate Similarity NPD8396 Approved
0.7394 Intermediate Similarity NPD459 Clinical (unspecified phase)
0.7391 Intermediate Similarity NPD5559 Phase 2
0.7389 Intermediate Similarity NPD750 Phase 2
0.7385 Intermediate Similarity NPD32 Approved
0.7385 Intermediate Similarity NPD31 Approved
0.7385 Intermediate Similarity NPD4037 Approved
0.7385 Intermediate Similarity NPD5901 Discontinued
0.7385 Intermediate Similarity NPD4036 Approved
0.7385 Intermediate Similarity NPD4039 Approved
0.7385 Intermediate Similarity NPD4122 Approved
0.7385 Intermediate Similarity NPD4034 Approved
0.7385 Intermediate Similarity NPD4038 Approved
0.7385 Intermediate Similarity NPD4035 Approved
0.7385 Intermediate Similarity NPD4033 Approved
0.7363 Intermediate Similarity NPD6203 Clinical (unspecified phase)
0.736 Intermediate Similarity NPD5658 Approved
0.7326 Intermediate Similarity NPD8431 Approved
0.7318 Intermediate Similarity NPD2781 Approved
0.731 Intermediate Similarity NPD7452 Approved
0.731 Intermediate Similarity NPD7222 Phase 2
0.731 Intermediate Similarity NPD7453 Approved
0.7306 Intermediate Similarity NPD9688 Approved
0.7306 Intermediate Similarity NPD9687 Approved
0.7303 Intermediate Similarity NPD2780 Approved
0.7303 Intermediate Similarity NPD2782 Approved
0.7297 Intermediate Similarity NPD5522 Clinical (unspecified phase)
0.7297 Intermediate Similarity NPD5728 Clinical (unspecified phase)
0.7292 Intermediate Similarity NPD2952 Discontinued
0.7291 Intermediate Similarity NPD3354 Phase 2
0.7287 Intermediate Similarity NPD8110 Clinical (unspecified phase)
0.7282 Intermediate Similarity NPD6975 Discontinued
0.7277 Intermediate Similarity NPD4418 Discontinued
0.7273 Intermediate Similarity NPD706 Phase 1
0.7268 Intermediate Similarity NPD2144 Approved
0.7264 Intermediate Similarity NPD2616 Phase 3
0.7264 Intermediate Similarity NPD2615 Phase 3
0.7259 Intermediate Similarity NPD3003 Approved
0.7241 Intermediate Similarity NPD7823 Clinical (unspecified phase)
0.7234 Intermediate Similarity NPD2383 Phase 1
0.7232 Intermediate Similarity NPD9398 Clinical (unspecified phase)
0.7225 Intermediate Similarity NPD4463 Approved
0.7225 Intermediate Similarity NPD4462 Approved
0.7222 Intermediate Similarity NPD6838 Clinical (unspecified phase)
0.7175 Intermediate Similarity NPD5255 Approved
0.7175 Intermediate Similarity NPD1554 Clinical (unspecified phase)
0.7174 Intermediate Similarity NPD6159 Phase 2
0.7173 Intermediate Similarity NPD994 Phase 2
0.7173 Intermediate Similarity NPD996 Phase 2
0.7172 Intermediate Similarity NPD4862 Clinical (unspecified phase)
0.717 Intermediate Similarity NPD7558 Phase 2
0.7168 Intermediate Similarity NPD4374 Clinical (unspecified phase)
0.7168 Intermediate Similarity NPD3100 Discontinued
0.716 Intermediate Similarity NPD9080 Approved
0.7151 Intermediate Similarity NPD3038 Discontinued
0.715 Intermediate Similarity NPD2125 Clinical (unspecified phase)
0.7143 Intermediate Similarity NPD5934 Clinical (unspecified phase)
0.7136 Intermediate Similarity NPD6290 Phase 2
0.7135 Intermediate Similarity NPD4076 Approved
0.7135 Intermediate Similarity NPD3813 Approved
0.7135 Intermediate Similarity NPD4079 Approved
0.7127 Intermediate Similarity NPD2844 Phase 3
0.7127 Intermediate Similarity NPD6872 Clinical (unspecified phase)
0.7126 Intermediate Similarity NPD2172 Phase 1
0.7122 Intermediate Similarity NPD2021 Discontinued
0.712 Intermediate Similarity NPD2380 Approved
0.712 Intermediate Similarity NPD2381 Approved
0.712 Intermediate Similarity NPD5100 Phase 3
0.712 Intermediate Similarity NPD2382 Approved
0.7114 Intermediate Similarity NPD3013 Phase 3
0.7114 Intermediate Similarity NPD3014 Clinical (unspecified phase)
0.7113 Intermediate Similarity NPD1219 Approved
0.7113 Intermediate Similarity NPD1218 Approved
0.711 Intermediate Similarity NPD4703 Approved
0.711 Intermediate Similarity NPD4702 Approved
0.71 Intermediate Similarity NPD2916 Discontinued
0.7095 Intermediate Similarity NPD1684 Approved
0.7095 Intermediate Similarity NPD1685 Approved
0.7087 Intermediate Similarity NPD3402 Phase 1
0.7086 Intermediate Similarity NPD6476 Clinical (unspecified phase)
0.7086 Intermediate Similarity NPD6158 Phase 2
0.7083 Intermediate Similarity NPD3923 Approved
0.7083 Intermediate Similarity NPD3922 Approved
0.7083 Intermediate Similarity NPD3921 Approved
0.7083 Intermediate Similarity NPD3924 Approved
0.7081 Intermediate Similarity NPD5751 Clinical (unspecified phase)
0.7081 Intermediate Similarity NPD3506 Approved
0.7081 Intermediate Similarity NPD3505 Approved
0.7079 Intermediate Similarity NPD7470 Discontinued
0.7079 Intermediate Similarity NPD5936 Approved
0.7079 Intermediate Similarity NPD5939 Approved
0.7068 Intermediate Similarity NPD5117 Phase 2
0.7059 Intermediate Similarity NPD3178 Discontinued
0.7053 Intermediate Similarity NPD6141 Clinical (unspecified phase)
0.7041 Intermediate Similarity NPD7621 Clinical (unspecified phase)
0.7037 Intermediate Similarity NPD2762 Phase 2
0.7035 Intermediate Similarity NPD5426 Phase 3
0.7022 Intermediate Similarity NPD9382 Approved
0.7022 Intermediate Similarity NPD9383 Approved
0.7021 Intermediate Similarity NPD2391 Clinical (unspecified phase)
0.7021 Intermediate Similarity NPD5596 Phase 2
0.7016 Intermediate Similarity NPD4021 Phase 2
0.7015 Intermediate Similarity NPD7947 Clinical (unspecified phase)
0.7 Intermediate Similarity NPD972 Clinical (unspecified phase)
0.6995 Remote Similarity NPD4502 Phase 2
0.6989 Remote Similarity NPD2882 Phase 1
0.6979 Remote Similarity NPD1213 Phase 3
0.6976 Remote Similarity NPD5902 Approved
0.6976 Remote Similarity NPD5903 Approved
0.6968 Remote Similarity NPD4204 Approved
0.6968 Remote Similarity NPD7414 Clinical (unspecified phase)
0.6968 Remote Similarity NPD4203 Approved
0.6966 Remote Similarity NPD276 Clinical (unspecified phase)
0.6961 Remote Similarity NPD862 Approved
0.6961 Remote Similarity NPD863 Approved
0.6961 Remote Similarity NPD861 Approved
0.6961 Remote Similarity NPD8093 Discontinued
0.6959 Remote Similarity NPD4551 Phase 2
0.6954 Remote Similarity NPD5999 Phase 2
0.6952 Remote Similarity NPD1620 Clinical (unspecified phase)
0.6951 Remote Similarity NPD9284 Approved
0.6949 Remote Similarity NPD2837 Discontinued
0.6944 Remote Similarity NPD4454 Phase 2
0.6944 Remote Similarity NPD1403 Approved
0.6944 Remote Similarity NPD1404 Approved
0.6943 Remote Similarity NPD5912 Clinical (unspecified phase)
0.6943 Remote Similarity NPD5913 Phase 3
0.6942 Remote Similarity NPD6147 Clinical (unspecified phase)

Structure

External Identifiers

PubChem CID   16054
ChEMBL   CHEMBL404923
ZINC  

Physicochemical Properties

Molecular Weight:  133.05
ALogP:  -0.8807
MLogP:  2.12
XLogP:  1.276
# Rotatable Bonds:  1
Polar Surface Area:  36.02
# H-Bond Aceptor:  1
# H-Bond Donor:  2
# Rings:  2
# Heavy Atoms:  10

Download Data

Data Type Select
General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs