CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Symphytum Tuberosum

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TCGAAACCTGCACAGCAGAACCACTCGCGAACTAGTTCATAAAACAACGGGCACTATCAAGTGTCGGTATTCCCTAGCATTTGATAGCGCCCAACGGCACTCGGCATTTTGCAAAGAGTGCTAAACAAACCCCCGGCGTGAGAAGCGCCAAGTAATACTTTAATGAGGGTCTGACCCAATCTCTCCCGCTCACGCGGTCAAGGGTATTGGGAATGGCTTCTTTCTAAATCACAACGACTCTCGGCAACGGATATCTTGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAAGCCATTAGGCTAAAGGCACGTCTGCCTGGGCGTCACGCATCCCGTCACCTCATCCCTAATTCTTGTGGATCGGTGGAATGTGACCTCCTGTTCCTAGTTGTGCAGTTGGTTAAAACTTGAGTATGTGGATTATGACTTCATGACAAGTGGTGGTTGGATAACAACTCTCGTCATGTCGTGTGCCAAACCTACGTGACTTTCAAGACCCTAAGGTGCAGGTTAACCTCATATTTTTGTTGGAAACTTGTTCTATG

Click for details-----ITS1

GAAACCTGCACAGCAGAACCACTCGCGAACTAGTTCATAAAACAACGGGCACTATCAAGTGTCGGTATTCCCTAGCATTTGATAGCGCCCAACGGCACTCGGCATTTTGCAAAGAGTGCTAAACAAACCCCCGGCGTGAGTAAGCGCCAAGTAATACTTTAATGAGGGTCTGACCCAATCTCTCCCGCTCACGCGGTCAAGGGAATTGGGAATGGCTTCTTTCTAAATCACAA

Click for details-----ITS2

ATCCCGTCACCTCATCCCTAATTCTTGTGGATCGGTGGAATGTGACCTCCTGTTCCTAGTTGTGCAGTTGGTTAAAACTTGAGTATGTGGATTATGACTTCATGACAAGTGGTGGTTGGATAACAACTCTCGTCATGTCGTGTGCCAAACCTACGTGACTTTCAAGACCCTAAGGTGCAGGTTAACCTCATATTTTTGTTGGAAACTTGTTCTATG

Taxonomic Information

Plant ID: NPO9866
Plant Latin Name: Symphytum Tuberosum
Taxonomy Genus: Symphytum
Taxonomy Family: Boraginaceae

Plant External Links:

NCBI TaxonomyDB: 256504
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

China; Spain

Traditional Medicine System:

TCM

Geographical Distribution

China; Spain

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

47 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

11 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)