Plant ID: NPO9623
Plant Latin Name: Hypericum Erectum
Taxonomy Genus: Hypericum
Taxonomy Family: Hypericaceae
NCBI TaxonomyDB:
282539
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC70957
Ingredient ID: NPC275463
Ingredient ID: NPC227839
Ingredient ID: NPC194055
Ingredient ID: NPC168494
Ingredient ID: NPC156910
Ingredient ID: NPC138883
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
Plant level | 5 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00131885 | Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel | Contraception | Hypericum Erectum | Plant level As single plant |
NCT00005013 | Treatment of Major Depression With St. John's Wort (Hypericum) | Major Depression | Hypericum Erectum | Plant level As single plant |
NCT00118833 | St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD) | Anxiety Disorders|Mental Health | Hypericum Erectum | Plant level As single plant |
NCT00048815 | Drug Therapy to Treat Minor Depression | Depression | Hypericum Erectum | Plant level As single plant |
NCT00557427 | Hypericum vs Fluoxetine for Mild to Moderate Adolescent Depression | Depression | Hypericum Erectum | Plant level As single plant |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
NCT00557427,NCT00005013,NCT00048815
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
NCT00118833
|