CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Vitex Agnus-Castus

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TGTCGAAACCTGCAAATGAGACCGCGAACACGTGTTTTACCGCAACGGGGACGCGGCGCGGGGCGAGCGTGCCTCCCTCCCGTCGCGTTCCCACCCCCGTCGGCACGGGCGCCATCGCCTCGTGTCGTGCGGGCTAACGAACCCCGGCGCGGCATGCGCCAAGGAAAACAAAAATGAAGCGTTCGCCGCCCGACGCCCCGTTCCGGAGCGCGCGGGCGGACGGTGCGCCTTTCTAATGTCAAAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAAGCCATTAGGCCGAGGGCACGTCTGCCTGGGCGTCACGCATCGCGTCGCCCCCCCTCCTGCGCATCGCGTCGCGATGGGGGGGCGGAGACTGGCCTCCCGTGCCCCTCGGCGCGGCTGGCCCAAATGCGATCCCTTCGGCGACGCACGTCACGACCAGTGGTGGTTGATCTCAACTCGCGTGCTGTCGTGCGGCGCGGCGTCGTCCGCAGTGGAGTCAACGATAACGATGACCCAACGGTGCATGCGCGCCTACGACC

Click for details-----ITS1

Click for details-----ITS2

ATCGCGTCGCCCCCCCTCCTGCGCATCGCGTCGCGATGGGGGGGCGGAGACTGGCCTCCCGTGCCCCTCGGCGCGGCTGGCCCAAATGCGATCCCTTCGGCGACGCACGTCACGACCAGTGGTGGTTGATCTCAACTCGCGTGCTGTCGTGCGGCGCGGCGTCGTCCGCAGTGGAGTCAACGATAACGATGACCCAACGGTGCATGCGCGCCTACGACC

Taxonomic Information

Plant ID: NPO7728
Plant Latin Name: Vitex Agnus-Castus
Taxonomy Genus: Vitex
Taxonomy Family: Lamiaceae

Plant External Links:

NCBI TaxonomyDB: 54477
Plant-of-the-World-Online: 865568-1

Used in Medicines

Country/Region:

Brazil; Australia; Italy; India; France; Jordan; Germany

Traditional Medicine System:

Unani; Homeopathy

Medicinal Functions:

Anaphrodisiac; Aphrodisiac; Diaphoretic; Diuretic; Febrifuge; Galactogogue; Infertility; Ophthalmic; Sedative; Stomachic; Women's complaints

Geographical Distribution

Brazil; Afghanistan; Italy; Turkmenistan; France; Peru; Australia; Iran; Algeria; Cuba; Russia; Jordan; Germany; Dominican Republic; Iraq; Spain; Libya; Turkey; United States; Morocco; Haiti; Bulgaria; Pakistan; Albania; Honduras; Mexico; Egypt; Nicaragua; India; Tunisia; Greece; Cyprus

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

38 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

24 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)