Plant ID: NPO4893
Plant Latin Name: Aconitum Ciliare
Taxonomy Genus: Aconitum
Taxonomy Family: Ranunculaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC99056
Ingredient ID: NPC97209
Ingredient ID: NPC94687
Ingredient ID: NPC89801
Ingredient ID: NPC88470
Ingredient ID: NPC88446
Ingredient ID: NPC87597
Ingredient ID: NPC87288
Ingredient ID: NPC86331
Ingredient ID: NPC8504
Ingredient ID: NPC83935
Ingredient ID: NPC81965
Ingredient ID: NPC71930
Ingredient ID: NPC69732
Ingredient ID: NPC69609
Ingredient ID: NPC66849
Ingredient ID: NPC62742
Ingredient ID: NPC62092
Ingredient ID: NPC60721
Ingredient ID: NPC60261
Ingredient ID: NPC60174
Ingredient ID: NPC56549
Ingredient ID: NPC55338
Ingredient ID: NPC54884
Ingredient ID: NPC54230
Ingredient ID: NPC51306
Ingredient ID: NPC49568
Ingredient ID: NPC48127
Ingredient ID: NPC4473
Ingredient ID: NPC43725
Ingredient ID: NPC36730
Ingredient ID: NPC34974
Ingredient ID: NPC33836
Ingredient ID: NPC33338
Ingredient ID: NPC33276
Ingredient ID: NPC31485
Ingredient ID: NPC312658
Ingredient ID: NPC310941
Ingredient ID: NPC306848
Ingredient ID: NPC305305
Ingredient ID: NPC304450
Ingredient ID: NPC302171
Ingredient ID: NPC302021
Ingredient ID: NPC302020
Ingredient ID: NPC300020
Ingredient ID: NPC298772
Ingredient ID: NPC296120
Ingredient ID: NPC291511
Ingredient ID: NPC290668
Ingredient ID: NPC290613
Ingredient ID: NPC29
Ingredient ID: NPC287766
Ingredient ID: NPC287764
Ingredient ID: NPC286569
Ingredient ID: NPC284525
Ingredient ID: NPC281470
Ingredient ID: NPC277941
Ingredient ID: NPC27699
Ingredient ID: NPC272290
Ingredient ID: NPC271472
Ingredient ID: NPC26777
Ingredient ID: NPC265482
Ingredient ID: NPC262376
Ingredient ID: NPC260441
Ingredient ID: NPC253157
Ingredient ID: NPC252519
Ingredient ID: NPC249360
Ingredient ID: NPC242406
Ingredient ID: NPC239421
Ingredient ID: NPC23790
Ingredient ID: NPC237384
Ingredient ID: NPC235258
Ingredient ID: NPC234791
Ingredient ID: NPC230301
Ingredient ID: NPC22767
Ingredient ID: NPC226473
Ingredient ID: NPC22573
Ingredient ID: NPC225453
Ingredient ID: NPC224601
Ingredient ID: NPC222627
Ingredient ID: NPC219233
Ingredient ID: NPC216737
Ingredient ID: NPC21442
Ingredient ID: NPC212106
Ingredient ID: NPC211468
Ingredient ID: NPC210262
Ingredient ID: NPC205595
Ingredient ID: NPC205
Ingredient ID: NPC20186
Ingredient ID: NPC198830
Ingredient ID: NPC19627
Ingredient ID: NPC194525
Ingredient ID: NPC192390
Ingredient ID: NPC18997
Ingredient ID: NPC187973
Ingredient ID: NPC184195
Ingredient ID: NPC179297
Ingredient ID: NPC174515
Ingredient ID: NPC173322
Ingredient ID: NPC172769
Ingredient ID: NPC17038
Ingredient ID: NPC170170
Ingredient ID: NPC168111
Ingredient ID: NPC16710
Ingredient ID: NPC166985
Ingredient ID: NPC166593
Ingredient ID: NPC165815
Ingredient ID: NPC163578
Ingredient ID: NPC160388
Ingredient ID: NPC159409
Ingredient ID: NPC15812
Ingredient ID: NPC149444
Ingredient ID: NPC149309
Ingredient ID: NPC145660
Ingredient ID: NPC145291
Ingredient ID: NPC14519
Ingredient ID: NPC145100
Ingredient ID: NPC140311
Ingredient ID: NPC139778
Ingredient ID: NPC137584
Ingredient ID: NPC1364
Ingredient ID: NPC128262
Ingredient ID: NPC124690
Ingredient ID: NPC124060
Ingredient ID: NPC118333
Ingredient ID: NPC117587
Ingredient ID: NPC115186
Ingredient ID: NPC112779
Ingredient ID: NPC110027
Ingredient ID: NPC108276
Ingredient ID: NPC106840
Ingredient ID: NPC104949
Ingredient ID: NPC101515
Ingredient ID: NPC100956
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 27 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00336947 | S-1 or Tegafur-Uracil in Treating Patients With Previously Treated Stage III or Stage IV Head and Neck Cancer | head and neck malignant neoplasia | Uracil (NPC27699) | NP level |
NCT00009815 | Combination Chemotherapy in Treating Patients With Advanced Solid Tumors | neoplasm | Uracil (NPC27699) | NP level |
NCT01082510 | Study of the Efficacy of Maintenance Therapy Using Uracil-tegafur (UFT) or Bacille Calmette-Guerin (BCG) for the Prevention of Recurrences of Superficial Bladder Cancer (EMBARK Study) | urinary bladder cancer | Uracil (NPC27699) | NP level |
NCT02447679 | Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence | hepatocellular carcinoma | Uracil (NPC27699) | NP level |
NCT00152191 | A Randomized Controlled Study of Postoperative Adjuvant Therapy of Uracil-tegafur (UFT) Compared With Cyclophosphamide/Methotrexate/5-fluorouracil (CMF) in Breast Cancer (NSAS-BC) | breast cancer | Uracil (NPC27699) | NP level |
NCT00003925 | Combination Chemotherapy In Treating Patients With Advanced Cancer | neoplasm | Uracil (NPC27699) | NP level |
NCT00660894 | Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma | rectum cancer | Uracil (NPC27699) | NP level |
NCT00152230 | A Randomized Controlled Study of Postoperative Adjuvant Chemotherapy of Uracil- Tegafur (UFT) Compared With Surgery Alone (NSAS-CC) | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT01037998 | UFUR (Tegafur/Uracil) Plus Iressa in Non-small-cell Lung Cancer | non-small cell lung carcinoma | Uracil (NPC27699) | NP level |
NCT00519688 | UFUR Plus Thalidomide for Advanced Hepatocellular Carcinoma | hepatocellular carcinoma | Uracil (NPC27699) | NP level |
NCT00905047 | Xeloda or UFT (Tegafur-uracil) With Folinic Acid in Advanced or Metastatic Colorectal Cancer | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT00152178 | The Comparative Trial of UFT + TAM With CMF + TAM in Adjuvant Therapy for Breast Cancer (CUBC) | breast cancer | Uracil (NPC27699) | NP level |
NCT03121313 | Maintenance Tegafur-uracil in Resected Oral Cavity Cancer With ECS+ | oral squamous cell carcinoma | Uracil (NPC27699) | NP level |
NCT00384800 | A Phase II Study of Tegafur/Uracil (UFUR®)Plus Thalidomide for the Treatment of Advanced or Metastatic Hepatocellular Carcinoma (HCC) | hepatocellular carcinoma | Uracil (NPC27699) | NP level |
NCT00705874 | Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or Lymphoma | cancer | Uracil (NPC27699) | NP level |
NCT00009828 | Paclitaxel Combined With Fluorouracil-Uracil and Leucovorin in Treating Patients With Solid Tumors | neoplasm | Uracil (NPC27699) | NP level |
NCT00005608 | Fluorouracil-Uracil and Leucovorin in Treating Women With Metastatic Breast Cancer | breast cancer | Uracil (NPC27699) | NP level |
NCT01262274 | Randomized Phase II Trial of Anastrozole Plus Metronomic Tegafur-uracil as Neo-adjuvant Therapy in Postmenopausal Breast Cancer | breast neoplasm | Uracil (NPC27699) | NP level |
NCT00385970 | A Phase III Trial Comparing UFT+PSK to UFT+LV in Stage IIB, III Colorectal Cancer | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT00152243 | A Randomized Controlled Study of Postoperative Adjuvant Chemotherapy of Uracil- Tegafur (UFT) Compared With Surgery Alone (NSAS-GC) | gastric cancer | Uracil (NPC27699) | NP level |
NCT00037089 | A Phase II Study of Paclitaxel, UFT, and Leucovorin in Patients With Metastatic Esophageal Cancer | neoplasm of esophagus | Uracil (NPC27699) | NP level |
NCT00855881 | Metronomic Chemotherapy With Tegafur/Uracil for Head and Neck Squamous Cell Carcinoma | head and neck malignant neoplasia | Uracil (NPC27699) | NP level |
NCT00004860 | Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT00378716 | Combination Chemotherapy in Treating Patients With Resected Colon Cancer | colorectal carcinoma | Uracil (NPC27699) | NP level |
NCT01539018 | Sorafenib Plus Tegafur-uracil (UFT) Versus Sorafenib as First Line Systemic Treatment for Patients With Advanced Stage HCC, Unresectable & Not Eligible for Local Ablation and/or TACE | hepatocellular carcinoma | Uracil (NPC27699) | NP level |
NCT00002801 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer | colorectal carcinoma | Uracil (NPC27699) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
NCT00004860,NCT00660894,NCT00152230,NCT00378716,NCT00002801,NCT00905047,NCT00385970
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT00519688,NCT02447679,NCT01539018,NCT00384800
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT00003925,NCT00009815,NCT00009828
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
NCT00005608,NCT00152191,NCT00152178
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
NCT00855881,NCT00336947
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
DRD3
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
DRD3
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
DRD3
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
DRD3
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
F2
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
DRD3
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
DRD3
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
F2
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
DRD3
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
DRD3
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
DRD3
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
DRD3
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
DRD3
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
F2
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
DRD3
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
DRD3
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
DRD3
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
DRD3
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
DRD3
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
F2
|
Psychoactive substances use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G |
DRD3
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
F2
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
F2
|
Gastroduodenal motor/secretory disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41 |
DRD3
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT01262274
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
NCT00152243
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
NCT00037089
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT01082510
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT00207831
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00705874
|
Squamous cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B60-2D01 |
NCT03121313
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT01037998
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
DRD3
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
F2
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
F2
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HSD17B10
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
F2
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
F2
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
F2
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
F2
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
F2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
F2
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
F2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
F2
|