Plant ID: NPO21507
Plant Latin Name: Ephedra Intermedia
Taxonomy Genus: Ephedra
Taxonomy Family: Ephedraceae
NCBI TaxonomyDB:
173278
Plant-of-the-World-Online:
n.a.
Antiasthmatic; Antidote; Antihydrotic; Diaphoretic; Diuretic; Vasoconstrictor; Vasodilator
India; China
Ingredient ID: NPC95039
Ingredient ID: NPC89956
Ingredient ID: NPC86477
Ingredient ID: NPC85339
Ingredient ID: NPC82843
Ingredient ID: NPC69934
Ingredient ID: NPC67485
Ingredient ID: NPC329501
Ingredient ID: NPC304761
Ingredient ID: NPC304078
Ingredient ID: NPC303611
Ingredient ID: NPC302731
Ingredient ID: NPC300205
Ingredient ID: NPC293799
Ingredient ID: NPC290515
Ingredient ID: NPC287902
Ingredient ID: NPC28677
Ingredient ID: NPC286400
Ingredient ID: NPC284039
Ingredient ID: NPC281090
Ingredient ID: NPC278552
Ingredient ID: NPC274769
Ingredient ID: NPC2724
Ingredient ID: NPC26974
Ingredient ID: NPC269340
Ingredient ID: NPC260382
Ingredient ID: NPC260061
Ingredient ID: NPC248874
Ingredient ID: NPC246757
Ingredient ID: NPC238247
Ingredient ID: NPC23706
Ingredient ID: NPC235589
Ingredient ID: NPC228400
Ingredient ID: NPC226779
Ingredient ID: NPC226778
Ingredient ID: NPC226096
Ingredient ID: NPC223673
Ingredient ID: NPC223576
Ingredient ID: NPC222505
Ingredient ID: NPC218168
Ingredient ID: NPC216630
Ingredient ID: NPC214584
Ingredient ID: NPC214201
Ingredient ID: NPC214200
Ingredient ID: NPC213063
Ingredient ID: NPC213
Ingredient ID: NPC199972
Ingredient ID: NPC195713
Ingredient ID: NPC182570
Ingredient ID: NPC182566
Ingredient ID: NPC173019
Ingredient ID: NPC171437
Ingredient ID: NPC164708
Ingredient ID: NPC164514
Ingredient ID: NPC150254
Ingredient ID: NPC149172
Ingredient ID: NPC148086
Ingredient ID: NPC147000
Ingredient ID: NPC143274
Ingredient ID: NPC143253
Ingredient ID: NPC124830
Ingredient ID: NPC121126
Ingredient ID: NPC108607
Ingredient ID: NPC108606
Ingredient ID: NPC108561
Ingredient ID: NPC10286
Ingredient ID: NPC10285
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 2 | CYP2C9 | Cytochrome P450 2C9 | P11712 | CHEMBL3397 |
Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
Therapeutic Target | Fatty acid binding protein family | FABP4 | Fatty acid binding protein adipocyte | P15090 | CHEMBL2083 |
Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Therapeutic Target | Nicotinic acetylcholine receptor | CHRNA3 | Neuronal acetylcholine receptor subunit alpha-3 | P32297 | CHEMBL3068 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Therapeutic Target | Peptide receptor (family A GPCR) | TSHR | Thyroid stimulating hormone receptor | P16473 | CHEMBL1963 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2A | Alpha-2a adrenergic receptor | P08913 | CHEMBL1867 |
Therapeutic Target | Small molecule receptor (family C GPCR) | GABBR1 | GABA-B receptor 1 | Q9UBS5 | CHEMBL2064 |
Therapeutic Target | Transcription factor | HIF1A | Hypoxia-inducible factor 1 alpha | Q16665 | CHEMBL4261 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 352 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT02840435 | Study on Sit to Quit Phone Intervention | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01478230 | An Exploratory Study Comparing Two Nicotine Inhalers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03059940 | Smoking Cessation Intervention During Low Dose CT (LDCT) Screening for Lung Cancer | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02905734 | Nicotine Replacement Therapy in Nicotine-dependent Arrestees | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00001925 | Effect of Alcohol on Tremors | Tremor | Alcohol (NPC2724) | NP level |
NCT02587312 | Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00873392 | Efficacy of Transdermal Nicotine, on Motor Symptoms in Advanced Parkinson's Disease | Parkinson disease | Nicotine (NPC182570) | NP level |
NCT01160848 | Photoactive Porphyrins (PAP) Levels After Topical Visonac Application in Acne Patients | acne | Alcohol (NPC2724) | NP level |
NCT03165942 | Neuroendocrine Response to Oral Alcohol Administration | alcohol abuse | Alcohol (NPC2724) | NP level |
NCT01536704 | Nicotine Lozenge Bioequivalence Study | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00851357 | Telephone Counseling and the Distribution of Nicotine Patches to Smokers | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02710097 | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II | cannabis dependence | Alcohol (NPC2724) | NP level |
NCT00296647 | Smoking Cessation Intervention: Effectiveness in Primary Care | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00471679 | Ethanol-Lock Treatment in Preventing Central Venous Catheter Infections in Patients With High-Risk Neuroblastoma | neuroblastoma | Alcohol (NPC2724) | NP level |
NCT02964182 | Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01989507 | Very Low-Nicotine Cigarettes in Smokers With SUD | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03294460 | Nicotinic Receptor Genetic Variation and Alcohol Reward | alcohol drinking | Alcohol (NPC2724) | NP level |
NCT00888459 | A Pilot Study Evaluating Nicotine Lozenges and Self Help | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01101412 | Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies | infection | Alcohol (NPC2724) | NP level |
NCT05335915 | Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00680459 | Ethanol Locks for the Treatment of Central Venous Line Infections | infection | Alcohol (NPC2724) | NP level |
NCT01586962 | Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI | respiratory tract infectious disorder | Pseudoephedrine (NPC147000) | NP level |
NCT01065506 | Smoking Termination Enhancement Project (STEP) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03272685 | Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01475331 | The CHARM Trial: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts | Pancreatic cysts | Alcohol (NPC2724) | NP level |
NCT01560754 | Disease-modifying Potential of Transdermal NICotine in Early Parkinson's Disease | Parkinson disease | Nicotine (NPC182570) | NP level |
NCT04251221 | Measuring the Neuroimmune Response to Alcohol | alcohol drinking | Alcohol (NPC2724) | NP level |
NCT02927847 | Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04003805 | Biomarkers of Exposure and Effect in Standardized Research E-cigarette (SREC) Users | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00240812 | A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting | enuresis | Pseudoephedrine Hydrochloride (NPC150254) | NP level |
NCT05024747 | A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03000387 | Personalized Dosing of Nicotine Replacement (NRT to Effect) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01184664 | Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study) | smoking cessation;nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01054859 | A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects. | erectile dysfunction | Alcohol (NPC2724) | NP level |
NCT03482583 | Tobacco Use Treatment in Cancer Patients | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02081144 | Texting to Promote Tobacco Abstinence in Emergency Department Smokers: A Pilot Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04554433 | New Treatment for COVID-19 Using Ethanol Vapor Inhalation . | COVID-19 | Alcohol (NPC2724) | NP level |
NCT01296698 | Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03879889 | Smoking Reduction Intervention for Smoking Parents of Paediatric Patients in Hong Kong | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02997657 | Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial | smoking cessation | Nicotine (NPC182570) | NP level |
NCT05233228 | Mobile Health Technology for Personalized Tobacco Cessation Support in Laos | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00969137 | Sensitivity to Intravenous Nicotine: Genetic Moderators | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00543881 | Telemedical Interventional Monitoring in Heart Failure | heart failure | Nicotine (NPC182570) | NP level |
NCT00437606 | A Study of the Pharmacokinetics/Pharmacodynamics of GK Activator (2) in Type 2 Diabetes Patients With Hepatic Impairment. | type 2 diabetes mellitus | Alcohol (NPC2724) | NP level |
NCT03860077 | Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00091468 | Nicotine Treatment of Mild Cognitive Impairment (MCI) | memory impairment | Nicotine (NPC182570) | NP level |
NCT03640507 | Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline | infection | Alcohol (NPC2724) | NP level |
NCT02355665 | Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00887367 | EtOH Interaction Study | substance dependence | Alcohol (NPC2724) | NP level |
NCT03168191 | Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02721082 | Changing the Default for Tobacco Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03580525 | Nicotine Delivery Rate and Its Abuse Potential: Impact of Menthol | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02955329 | Vaping THC From Electronic Cigarettes | cannabis dependence | Nicotine (NPC182570) | NP level |
NCT00553709 | Study of Nicotine for the Prevention of PONV | post operative nausea and vomiting | Nicotine (NPC182570) | NP level |
NCT02018263 | Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans | cocaine dependence | Nicotine (NPC182570) | NP level |
NCT00664755 | Menstrual Cycle Effects on Smoking Cessation and Cue Reactivity | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01372254 | Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00105482 | Targeted Interventions for Weight-Concerned Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01375556 | Genetics of the Acute Response to Alcohol in Social Drinkers | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT04608201 | Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients | COVID-19 | Nicotine (NPC182570) | NP level |
NCT04535362 | Nicotine's Potential Abuse With Menthol | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03432312 | Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00223691 | Treatment of Orthostatic Hypotension in Autonomic Failure | orthostatic hypotension | Pseudoephedrine (NPC147000) | NP level |
NCT02250534 | Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01560507 | Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02411175 | The Efficacy of Individualised Homeopathic Treatment on Constipation | Constipation | Alcohol (NPC2724) | NP level |
NCT03503773 | The TARGET BP OFF-MED Trial | hypertension | Alcohol (NPC2724) | NP level |
NCT00326781 | Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02720445 | Memory Improvement Through Nicotine Dosing (MIND) Study | Cognitive impairment | Nicotine (NPC182570) | NP level |
NCT03635333 | Effects of E-Cigarette Flavors on Adults TCORS 2.0 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05470972 | Relation Between Ethanol Sclerotherapy for Endometrioma Systemic Immune Milieu | endometriosis | Alcohol (NPC2724) | NP level |
NCT02371850 | Transdermal Patch CVD 1000: The Effect of Heat on Nicotine Release From Nicotine Patches in Adult Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00616746 | Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans | alcohol drinking | Nicotine (NPC182570) | NP level |
NCT01932996 | Enhancing Smoking Cessation in the Homeless Population | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05236894 | Appeal of Nicotine Pouches Versus Cigarettes in the Ohio Appalachia Population | carcinoma | Nicotine (NPC182570) | NP level |
NCT00879918 | Pharmacogenetics of Nicotine Metabolism in African-Americans | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00018187 | Combinations of Pharmacologic Smoking Cessation Treatments | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00931021 | Smoking Cessation Treatment for Head and Neck Cancer Patients | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00775944 | Trial Comparing Different Methods of Support With Stopping Smoking (PORTSSS/Stop Together Trial) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00377975 | "Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat | obesity | Ephedrine (NPC226778) | NP level |
NCT01075659 | Early Effects of a New Oral Nicotine Replacement Product and NiQuitin™ Lozenge | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02896400 | Optimizing Tobacco Dependence Treatment in the Emergency Department | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04488744 | Smoking by IV Pulsed Nicotine | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01819259 | Nicotine, Non-Smokers With and Without ADHD, and Genetics Study | attention deficit hyperactivity disorder | Nicotine (NPC182570) | NP level |
NCT04433767 | Depressed Mood Improvement Through Nicotine Dosing 2 | depressive disorder | Nicotine (NPC182570) | NP level |
NCT02213419 | Endoscopic Ultrasonography-guided Double Ethanol Lavage for Pancreatic Cysts: a Prospective Cohort Study | cystic, mucinous, and serous neoplasm | Alcohol (NPC2724) | NP level |
NCT00840242 | Smoking Reduction or Cessation With Nicotine Replacement Therapy | smoking cessation | Nicotine (NPC182570) | NP level |
NCT04124432 | Behavioral Pharmacology of Cannabis and Nicotine | cannabis dependence | Nicotine (NPC182570) | NP level |
NCT02482233 | The END Perioperative Smoking Pilot Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03808818 | Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices | in situ carcinoma | Nicotine (NPC182570) | NP level |
NCT05253573 | Mobile Health Technology for Personalized Tobacco Cessation Support Among Cancer Survivors in Laos | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01417429 | Galantamine Effects on Nicotine Responses in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01502306 | A Randomized Trial of Medi-Cal Beneficiaries Calling the California Smokers' Helpline | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00392379 | Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03856515 | Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes | carcinoma | Nicotine (NPC182570) | NP level |
NCT00967070 | Skin Sensitization Potential of a New Nicotine Patch | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02771587 | Interaction of Alcohol With Energy Drinks | alcohol-related disorders | Alcohol (NPC2724) | NP level |
NCT01847443 | Comparison of Pharmacokinetic Profiles of Two Nicotine Gum Formulations | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01186549 | The Effect of Combined Ephedrine and Lidocaine Pretreatment on Pain and Hemodynamic Changes Due to Propofol Injection | pain | Ephedrine (NPC226778) | NP level |
NCT00710034 | Efficacy of Oral Tobacco Products Compared to a Medicinal Nicotine | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04025918 | Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section | hypotension | Ephedrine (NPC226778) | NP level |
NCT01702519 | A Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04583410 | Efficacy of Nicotine in Preventing COVID-19 Infection | COVID-19;severe acute respiratory syndrome | Nicotine (NPC182570) | NP level |
NCT01314001 | Pharmacogenetics of Nicotine Addiction Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02501265 | Adaptive Pharmacotherapy for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02250664 | Project 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid Abusers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03163303 | Smoking Tobacco and Drinking Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00894166 | Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02046200 | Development of Ivermectin for Alcohol Use Disorders | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT02710331 | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III | cannabis dependence | Alcohol (NPC2724) | NP level |
NCT00276016 | The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579) | seasonal allergic rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT00801086 | Efficacy Study of Tempol to Prevent Hair Loss From Radiotherapy to the Brain | alopecia | Alcohol (NPC2724) | NP level |
NCT01517022 | Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosis | tuberculosis | Nicotine (NPC182570) | NP level |
NCT04974580 | Research and Innovation to Stop E-cigarette/Vaping in Young Adults | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03612960 | Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02384876 | Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age. | hypotension | Ephedrine (NPC226778) | NP level |
NCT03521141 | PRecision Interventions for SMoking in the SCCS | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01472965 | Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection | infection | Alcohol (NPC2724) | NP level |
NCT00307203 | Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01702532 | Nicotine Mouth Film for Craving Relief. | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00258479 | Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00657020 | Functional Magnetic Resonance Imaging (fMRI) Investigation of Nicotine Withdrawal Symptoms | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04696380 | Do Flavors Increase the Addiction Potential of Nicotine? | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01838460 | Sublingual Nicotine Tablets Compared With Swedish Snus | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02796391 | Facilitating Smoking Cessation With Reduced Nicotine Cigarettes | smoking cessation | Nicotine (NPC182570) | NP level |
NCT03290430 | End Nicotine Dependence Clinic | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00247585 | Hangover, Congeners, Sleep and Occupational Performance | neurobehavioral manifestations | Alcohol (NPC2724) | NP level |
NCT05060965 | Inpatient Smoking Cessation Pilot Program | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03492463 | The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00738595 | Phase II Study to Evaluate the Effectiveness of EVT 302 in Smoking Cessation. | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01451060 | Maternal and Neonatal Outcomes of the Use of Vasopressors to Treat Hypotension During Spinal Anesthesia for Cesarean | preeclampsia | Ephedrine (NPC226778) | NP level |
NCT03416348 | Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2 | Hyperhidrosis | Alcohol (NPC2724) | NP level |
NCT01783912 | Helping Those With Mental Illness Quit Smoking | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01085032 | Nicotine Patch Trial in Syrian Primary Care Settings | smoking cessation | Nicotine (NPC182570) | NP level |
NCT03257930 | Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules | thyroid nodule | Alcohol (NPC2724) | NP level |
NCT00032084 | S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery | lung cancer | Nicotine (NPC182570) | NP level |
NCT01457469 | Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05176418 | IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03421210 | Effects of Smoking Environments on Brain Reactivity | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04709471 | E-cigarette Nicotine Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01736085 | Providing Free Nicotine Patches to Quitline Smokers | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01806779 | Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00000454 | Smoking Cessation in Alcoholism Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02577718 | Safety and Effectiveness of Novel Nitroglycerin Based Catheter Lock Solution | infection | Alcohol (NPC2724) | NP level |
NCT03575403 | Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate) | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT02906644 | Combination Nicotine Patch / Lorcaserin for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02227329 | Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition | infection | Alcohol (NPC2724) | NP level |
NCT00881127 | To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fasting Conditions | allergic disease | Pseudoephedrine (NPC147000) | NP level |
NCT03972137 | Heart Rate Variability Biofeedback for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02910414 | TARGET BP I Clinical Trial | hypertension | Alcohol (NPC2724) | NP level |
NCT00586482 | Pilot Study: Preoperative Nicotine Lozenges | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00507975 | Study of Nicotine Patch in Pregnancy (SNIPP) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02487953 | Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00622752 | Effects of EVT 302 With or Without NRT on Craving and Withdrawal in Healthy Male Smokers Deprived of Cigarettes | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00965913 | Cumulative Skin Irritation Potential of a New 15 mg Nicotine Patch | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02158039 | Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms | cystic, mucinous, and serous neoplasm | Alcohol (NPC2724) | NP level |
NCT05159934 | Nicotine Differences in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00046813 | Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01018394 | Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00086411 | Comparing Smoking Treatment Programs for Lighter Smokers - 1 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00749463 | Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00755716 | Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01857531 | Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00734617 | Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01669122 | Pharmacokinetic Study of 4 mg Nicotine Lozenge. | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02414581 | Mouthwash With Chlorhexidine 0.12%/Ethyl Alcohol 7% Compared to Ethyl Alcohol 7% | neutropenia | Alcohol (NPC2724) | NP level |
NCT02245308 | Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00793468 | Relapse Prevention Study in Newly Abstinent Smokers | substance dependence | Nicotine (NPC182570) | NP level |
NCT00699556 | Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy | alcohol drinking | Nicotine (NPC182570) | NP level |
NCT00704496 | The Effect of Pseudoephedrine on Rhinitis and Sleep | rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT01621022 | Bupropion Alone or Combined With Nicotine Gum | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03253887 | Ethanol-lock Therapy for the Prevention of Non-tunneled Catheter-related Infection in Pediatric Patients | infection | Alcohol (NPC2724) | NP level |
NCT02919579 | A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder | major depressive disorder | Alcohol (NPC2724) | NP level |
NCT00000447 | Behavioral/Drug Therapy for Alcohol-Nicotine Dependence (Naltrexone/Nicotine Patch) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04521647 | Effects of Menthol in E-cigarettes on Smoking Behaviors | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01592695 | Tailored Tobacco Quitline for Rural Veterans | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02182518 | Epinastine + Pseudoephedrine SR (Slow Release) Versus Epinastine Alone in Patients With Perennial Allergic Rhinitis | Rhinitis, Allergic, Perennial | Pseudoephedrine (NPC147000) | NP level |
NCT02356913 | Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00000437 | Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00963443 | Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold | common cold | Pseudoephedrine (NPC147000) | NP level |
NCT01438944 | Evaluation of Transdermal Nicotine Replacement Therapy (NRT) Activity Through Metabolic Induction | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01306721 | Fexofenadine HCL - Pseudoephedrine HCL Combination Versus Allegra in Patients With Seasonal Allergic Rhinitis | seasonal allergic rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT01980550 | Association of Functional COMT Val108/Met Polymorphism With Smoking Cessation in Nicotine Replacement Therapy | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00806260 | A Study to Evaluate How VI-0521 Affect Psychomotor Performance in Healthy Overweight and Obese Subjects. | obesity | Alcohol (NPC2724) | NP level |
NCT00297492 | Gradual vs. Abrupt Cessation Treatment for Smoking | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01208935 | Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01199380 | Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04084210 | Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01058876 | Comparison of Low Yield Cigarettes in African Americans vs. Whites | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01205074 | ¹³C-Methacetin Breath Test (MBT) Methodology Study | cirrhosis of liver | Alcohol (NPC2724) | NP level |
NCT01867411 | Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04669392 | The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars | pulpitis | Alcohol (NPC2724) | NP level |
NCT04999631 | SADBE for Congenital Melanocytic Nevi | large congenital melanocytic nevus | Alcohol (NPC2724) | NP level |
NCT00000752 | Preventing Frequent Sinus Infections in HIV-Infected Patients | sinusitis | Pseudoephedrine Hydrochloride (NPC150254) | NP level |
NCT03069482 | Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04033237 | Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01091363 | Tobacco Dependence Treatment for Asian Americans | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00956943 | Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03131843 | Effectiveness of Alcohol Swabs for Preventing Infections During Vaccination | skin infection | Alcohol (NPC2724) | NP level |
NCT04946825 | Quit Smoking Study for People Who Use E-Cigarettes | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04262817 | The Interaction of Flavor With Nicotine Form in Adult Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00067158 | Smoking Cessation Treatment With Transdermal Nicotine Replacement Therapy - 1 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01509209 | Efficacy/Safety of Pseudoephedrine Plus Levocetirizine Versus Placebo in Patients With Vasomotor Rhinitis | vasomotor rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT03543137 | To Assess the Bioequivalence of the 4mg Prototype Mini Nicotine Lozenge to the Reference Product (Nicorette) in Healthy Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00108537 | Non-Nicotine Agents for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05206435 | Methadone-Maintained Smokers Switching to E-Cigarettes | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01907594 | Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00563342 | Catheters Dysfunction Rate After Instillation of Ethanol 60% Lock Solution in Tunneled Silicone Catheter of Chronic Hemodialysis Patients | chronic kidney disease | Alcohol (NPC2724) | NP level |
NCT03964350 | Behavior Brain Responses | alcohol drinking | Alcohol (NPC2724) | NP level |
NCT00673062 | Study of the Effect of SCH 900538 on Congestion in Subjects With Seasonal Allergic Rhinitis (Study P05031)(COMPLETED) | seasonal allergic rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT01926626 | Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00218296 | Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03897439 | Individualizing Pharmacotherapy for African American Smokers | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00061074 | Tobacco Cessation in Postmenopausal Women (Part II) - 2 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00037141 | Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate) | benign prostatic hyperplasia | Alcohol (NPC2724) | NP level |
NCT02082054 | StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study | seasonal allergic rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT03634839 | Effects of E-cigarette Flavors on Youth TCORS 2.0 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02147132 | Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02681510 | UW-CTRI Triple Medication Smoking Cessation Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00744913 | Study of Nicotine Replacement Therapy in Pregnancy | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00290290 | Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections | infection | Alcohol (NPC2724) | NP level |
NCT00064844 | Combination Nicotine Replacement for Alcoholic Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01289561 | Combined Effects of Alcohol and Caffeine | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT00939029 | Highdose Nicotine Patch Therapy for Smokeless Tobacco Use | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00985985 | Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01495819 | Nicotine Reinforcement and Aversion in Young Adult Light Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01292642 | Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence | cannabis dependence;nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01406223 | Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02709954 | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I | cannabis dependence | Alcohol (NPC2724) | NP level |
NCT00132236 | Nurse Smoking Cessation of Patients With Chronic Obstructive Pulmonary Disease (COPD) With Nicotine Replacement Therapy (NRT) and Behavioral Support | chronic obstructive pulmonary disease;nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01329614 | Effects of Nicotine Replacement and Repeated Cue Exposure on Cigarette Craving | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01104896 | Effect of Daily Nicotine Patch Application on Mechanical Ventilation Weaning in Smoking Patients | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01380691 | A Study of LY2216684 in Healthy Participants | major depressive disorder | Alcohol (NPC2724) | NP level |
NCT03757143 | Chlorhexidine-Alcohol Versus Povidone Iodine-Alcohol, Combined or Not With Use of a Bundle of New Devices, for Prevention of Intravascular-catheter Colonization and Catheter Failure | infection | Alcohol (NPC2724) | NP level |
NCT03047109 | Ephedrine and Phenylephrine for Spinal Hypotension | hypotension | Ephedrine (NPC226778) | NP level |
NCT00009854 | Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm | Central Nervous System Neoplasm | Alcohol (NPC2724) | NP level |
NCT02511704 | Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00764439 | Pilot Study of a New Nicotine Replacement Therapy | smoking cessation | Nicotine (NPC182570) | NP level |
NCT03408574 | The Nicotinic Cholinergic System and Cognitive Aging | aging | Nicotine (NPC182570) | NP level |
NCT00777569 | Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02232737 | Project 3, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in People With Current Affective Disorders | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02467543 | The Efficacy of Viburnum Opulus 3X in the Treatment of Primary Dysmenorrhea | Dysmenorrhea | Alcohol (NPC2724) | NP level |
NCT00000444 | Timing of Smoking Intervention in Alcohol Treatment (Nicotine Patch) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00715871 | Clinical Study of Smoke-Break Liquid Cigarettes | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01476202 | Provoked Craving Relief Study by NRT | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01654107 | Persistence-Targeted Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01898221 | Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation | atrial fibrillation;ventricular tachycardia | Alcohol (NPC2724) | NP level |
NCT00701207 | Study of Nicotine Patches in Patients With Sarcoidosis | pulmonary sarcoidosis | Nicotine (NPC182570) | NP level |
NCT02179034 | Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1 | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02271919 | Varenicline and Combined NRT for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03091699 | Effects of Exercise and Nicotine on Cognition in Smokers | smoking cessation | Nicotine (NPC182570) | NP level |
NCT04740008 | Impact of Low Nicotine Cigarette Messaging on Perceptions and Cigarette Choices | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05268419 | Efficacy and Safety of Ethanol Inhalation on COVID-19 Treatment (a Clinical Trial Study) | infection | Alcohol (NPC2724) | NP level |
NCT01444131 | Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01892813 | Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01664741 | Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01048944 | Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03432273 | Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02439944 | Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03538938 | Improving Quitline Support Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00006656 | Carmustine in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme | Central Nervous System Neoplasm | Alcohol (NPC2724) | NP level |
NCT01056926 | Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02419235 | The Effect of a Homoeopathic Complex on Blood Pressure in Refractory Hypertension | essential hypertension | Alcohol (NPC2724) | NP level |
NCT04999644 | Reduced Nicotine Cigarette Purchasing Decisions | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03442413 | Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03176784 | UW Quitting Using Intensive Treatment Study (QUITS) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00831155 | Extinction Based Treatment for Nicotine Dependence | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01136642 | Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05224050 | Heart Rate Variability Biofeedback for Smoking Cessation Treatment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01177852 | Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis | Cough;inflammation;rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT01034020 | Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03736343 | Impulsivity and Alcohol Response | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT00218283 | Nicotine Lozenge to Reduce Smokeless Tobacco Use | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05497700 | Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension | hypotension | Ephedrine (NPC226778) | NP level |
NCT00957918 | Study of NP002 in Subjects With Idiopathic Parkinson's Disease to Treat Dyskinesias Due to Levodopa Therapy | Parkinson disease | Nicotine (NPC182570) | NP level |
NCT03178422 | Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects | smoking cessation | Nicotine (NPC182570) | NP level |
NCT04063267 | Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00018161 | Treatment to Quit Smoking | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03611881 | Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00833404 | Smoking Cessation and Sexual Health in Men | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00364156 | Comparison of Standard Versus Extended Nicotine Patch Therapy for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00960778 | Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01287377 | Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00966901 | Photoirritation and Photoallergic Potential of a New Nicotine Patch | smoking cessation | Nicotine (NPC182570) | NP level |
NCT01443858 | Meclizine as a Potential Smoking Cessation Treatment | smoking cessation | Nicotine (NPC182570) | NP level |
NCT00967174 | Cumulative Skin Irritation Potential of a New 25 mg Nicotine Patch | smoking cessation | Nicotine (NPC182570) | NP level |
NCT05351606 | Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01429129 | Randomized Controlled Trial of Mailed Nicotine Replacement Therapy to Canadian Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04856566 | Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT02521662 | The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation | smoking cessation | Nicotine (NPC182570) | NP level |
NCT03838575 | ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions | infection | Alcohol (NPC2724) | NP level |
NCT03541044 | A Bioequivalence Study of Two Nicotine Lozenges in Fasting Conditions in Healthy Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04584684 | Mouth Rinses for Inactivation of COVID-19 | COVID-19 | Alcohol (NPC2724) | NP level |
NCT04490057 | A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01744106 | A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold | common cold | Pseudoephedrine Hydrochloride (NPC150254) | NP level |
NCT00616746 | Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans | alcohol drinking | Alcohol (NPC2724) | NP level |
NCT05154669 | Integrating Financial Coaching and Smoking Cessation Coaching | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03192306 | Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores | Herpes Labialis | Alcohol (NPC2724) | NP level |
NCT03216954 | Influence of n-Acetylcysteine Maintenance on Alcohol Effects | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT01050569 | Innovative Interventions for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01506908 | Provoked Craving Assessment | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02622126 | Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia | blood coagulation disease;hemorrhage | Ephedrine (NPC226778) | NP level |
NCT00295334 | Moderate Alcohol Intake Among Patients With Type 2 Diabetes | type 2 diabetes mellitus | Alcohol (NPC2724) | NP level |
NCT01006863 | Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study | hypotension | Ephedrine (NPC226778) | NP level |
NCT00881634 | To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fed Conditions | allergic disease | Pseudoephedrine (NPC147000) | NP level |
NCT02149901 | Water and Sudafed in Autonomic Failure | multiple system atrophy | Pseudoephedrine (NPC147000) | NP level |
NCT02942212 | Health Literacy and Smoking Cessation in Low-SES Diverse Smokers - Project HALT II | smoking cessation | Nicotine (NPC182570) | NP level |
NCT05018117 | Effects of Nicotine and Attention on Frequency Tuning in Auditory Cortex | aging | Nicotine (NPC182570) | NP level |
NCT04598594 | Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients | COVID-19;severe acute respiratory syndrome | Nicotine (NPC182570) | NP level |
NCT05130788 | WeChat Quit Coach Pilot Study | smoking cessation | Nicotine (NPC182570) | NP level |
NCT02162849 | Reward Sensitivity and Pharmacotherapy for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00004551 | Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch) | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01539434 | Behavioral Intervention to Maintain Physical Capacity and Activity in Patients With Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Nicotine (NPC182570) | NP level |
NCT01303861 | Concurrent Bupropion / Varenicline for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01186172 | Ethanol Lock for the Salvage of Infected Long-term Vascular Access | bacteriemia | Alcohol (NPC2724) | NP level |
NCT03809897 | Varenicline for Smoking Cessation in Hospitalized Patients With Psychiatric Disorders | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04590404 | Metabolism Informed Smoking Treatment: The MIST RCT | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03262233 | Stress Neuroadaptation in Tobacco Dependence | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04020718 | Engagement With an Adaptive Mobile Health Smoking Cessation Intervention | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02048215 | Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity | obesity | Ephedrine (NPC226778) | NP level |
NCT05311085 | Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion) | smoking cessation | Nicotine (NPC182570) | NP level |
NCT03010917 | Fish Oil vs. Placebo on Subjective Effects of Alcohol | alcohol dependence | Alcohol (NPC2724) | NP level |
NCT05487807 | Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT05301660 | Effect of Nicotine Transdermal Patch on Cognitive Function and Glycolipid Metabolism in Non-smoking Schizophrenia | schizophrenia | Nicotine (NPC182570) | NP level |
NCT02019459 | Very Low Nicotine Cigarettes in Smokers With Schizophrenia | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01241032 | Phase I Study to Investigate the Alcohol Interaction of DA8159 | erectile dysfunction | Alcohol (NPC2724) | NP level |
NCT00469079 | Health Effects of SLT, Cigarette Smoking, and New Tobacco Products | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01172561 | Community Awareness Resources and Education - Project 1 | cervical cancer | Nicotine (NPC182570) | NP level |
NCT01321931 | Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03243630 | Effects of Flavors on Nicotine Reinforcement in Smokers | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04969198 | UW Withdraw From Tobacco Study | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT04126135 | Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT02893345 | Safe@Home: A Self-Management Program for Individuals With TBI and Their Families | injury | Nicotine (NPC182570) | NP level |
NCT03361384 | Alcohol and Implicit Process in Sexual Risk Behavior in MSM | alcohol drinking | Alcohol (NPC2724) | NP level |
NCT02265874 | Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study | sarcoidosis | Nicotine (NPC182570) | NP level |
NCT02277730 | A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability | hypotension | Ephedrine (NPC226778) | NP level |
NCT00784433 | The CArdiovasCulAr Diabetes & Ethanol (CASCADE) Trial | prediabetes syndrome | Alcohol (NPC2724) | NP level |
NCT03404596 | Applying mHealth to Tobacco-related Health Disparities | smoking cessation | Nicotine (NPC182570) | NP level |
NCT04994444 | Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00018148 | Combined Nortriptyline and Transdermal Nicotine for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT03865121 | Pilot Trial of Transnasal Nicotine in Parkinson Disease | Parkinson disease | Nicotine (NPC182570) | NP level |
NCT00332644 | Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00527020 | First Time in Human Study With GSK1018921 | schizophrenia | Nicotine (NPC182570) | NP level |
NCT03083184 | Evaluation of the Efficacy of an inTerdialytic "Ethanol 40% v/v - enoxapaRin 1000 U/mL" Lock solutioN to Prevent Tunnelled Catheter Infections in Chronic Hemodialysis Patients | infection | Alcohol (NPC2724) | NP level |
NCT00804687 | An Efficacy Study of JNJ-39220675 and Pseudoephedrine in Participants With Allergic Rhinitis | allergic rhinitis | Pseudoephedrine (NPC147000) | NP level |
NCT01047527 | An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01484717 | Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT01351766 | Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation | nicotine dependence | Nicotine (NPC182570) | NP level |
NCT00295984 | Nicotine Skin Patch in Treating Patients With Kaposi's Sarcoma | sarcoma | Nicotine (NPC182570) | NP level |
NCT02428062 | Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly | Cognitive impairment | Ephedrine (NPC226778) | NP level |
NCT01985321 | Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores | Herpes Labialis | Alcohol (NPC2724) | NP level |
NCT04606797 | Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada | nicotine dependence | Nicotine (NPC182570) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
FABP5,GABBR2,CHRNA3,GABBR1,BLM,ADRA2A,CHRNA7,OR51E2,HIF1A
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
NCT01509209,NCT00704496,NCT00673062,NCT02082054,NCT00276016,NCT01306721,NCT00804687,NCT01177852
|
Alcohol dependenceDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40.2 |
NCT04856566,NCT03575403,NCT03736343,NCT03010917,NCT02046200,NCT01375556,NCT03216954,NCT01289561
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CHRNA4,TDP1,FABP5,HSD17B10,TSHR,GABBR2,CHRNA3,ALOX15
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
GABBR2,CHRNA3,BLM,ALOX15,OR51E2,CYP2C9,HIF1A,CBR1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CHRNA4,FABP5,GABBR2,BLM,ADRA2A,CHRNA7,OR51E2,CBR1
|
HypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA20-BA21 |
CHRNA4
NCT04025918,NCT05497700,NCT01006863,NCT02277730,NCT02384876,NCT03047109 |
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
GABBR1,CHRNA7,ADRA2A,CHRNA2,CHRFAM7A,CHRNA4,GABBR2
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
FABP5,GABBR2,CYP2C9,FABP5,TSHR,GABBR2,OR51E2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
FABP5,GABBR2,FABP4,CHRNA3,BLM,OR51E2,GABBR2
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
CHRNA7,GABBR1,CHRFAM7A,GABBR2
NCT00527020,NCT05301660 |
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
CHRFAM7A,CHRNA7
NCT03865121,NCT00873392,NCT00957918,NCT01560754 |
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
GABBR2,GABBR1,ADRA2A
NCT00887367,NCT03165942,NCT00793468 |
Alcohol beverageDisease Category: X.Extension CodesDisease ICD-11 Code: XM1A61 |
NCT03361384,NCT03294460,NCT00616746,NCT00699556,NCT03964350,NCT04251221
|
Cannabis use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C41 |
NCT04124432,NCT02709954,NCT02710097,NCT02955329,NCT02710331,NCT01292642
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
TDP1,FABP5,TSHR,GABBR2,CHRNA3,ALOX15
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
FABP5,CHRNA3,BLM,ADRA2A,CHRNA7,OR51E2
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
FABP5,FABP4,CHRNA3,BLM,CHRNA7,OR51E2
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
TSHR,BLM,CHRNA7,OR51E2,CYP2C9,CBR1
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
TDP1,SMN1,ALOX15,ADRA2A,OR51E2,CBR1
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
TSHR,GABBR2,BLM,ADRA2A,CYP2C9,CBR1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
FABP5,CHRNA3,BLM,CYP2C9,HIF1A,SMN1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04584684,NCT04598594,NCT04554433,NCT04608201,NCT04583410
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CHRNA4,CHRNA3,ALOX15,CHRNA7,CYP2C9
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
FABP5,HSD17B10,ALOX15,CHRNA2,CYP2C9
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
CHRFAM7A,CHRNA7,CHRNA4,CHRNA2
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
CHRNA4,ADRA2A
NCT01819259 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
HIF1A
NCT03503773,NCT02910414 |
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
CHRNA7,CHRNA4,CHRFAM7A
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
CHRFAM7A,CHRNA7,CBR1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
HIF1A,GABBR1,GABBR2
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT02213419,NCT02158039,NCT01177852
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00806260,NCT00377975,NCT02048215
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP2C9,BLM,GABBR2
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
ALOX15,OR51E2,FABP5
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM,ALOX15,CYP2C9
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
CHRNA4,GABBR2,BLM
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
FABP5,TSHR,BLM
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
GABBR2,GABBR1
|
Adaptive immunity immunodeficiencyDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01 |
CHRFAM7A,CHRNA7
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
CHRFAM7A,CHRNA7
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
GABBR2,GABBR1
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
CHRFAM7A,CHRNA7
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
CHRFAM7A,CHRNA7
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
GABBR2,GABBR1
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CHRNA7,CHRFAM7A
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
GABBR2,GABBR1
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
CHRFAM7A,CHRNA7
|
Sex development malformative disorderDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2A |
CHRFAM7A,CHRNA7
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ADRA2A
NCT01186549 |
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
GABBR2,GABBR1
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
GABBR2,GABBR1
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
GABBR2,GABBR1
|
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
CHRFAM7A,CHRNA7
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
GABBR2
NCT00000752 |
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT01539434,NCT00132236
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04598594,NCT04583410
|
Herpes simplex labialisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00.01 |
NCT01985321,NCT03192306
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01744106,NCT00963443
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT00881634,NCT00881127
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00006656,NCT00009854
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT00437606,NCT00295334
|
SarcoidosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B20 |
NCT00701207,NCT02265874
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT01380691,NCT02919579
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT05018117,NCT03408574
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT02720445,NCT02428062
|
Male erectile dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA01.1 |
NCT01241032,NCT01054859
|
Neuroendocrine carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C34 |
NCT03856515,NCT05236894
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
CYP2C9,TSHR
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
TSHR,BLM
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM,ALOX15
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
CHRNA2,CBR1
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ALOX15,BLM
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4,GABBR2
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
CHRNA4,HIF1A
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
CHRNA4,CHRFAM7A,CHRNA2,CHRNA7
NCT02147132,NCT05233228,NCT00000454,NCT03272685,NCT02905734,NCT00715871,NCT02232737,NCT00956943,NCT01783912,NCT01314001,NCT00392379,NCT02439944,NCT03000387,NCT00000437,NCT01621022,NCT05159934,NCT01506908,NCT02250664,NCT04003805,NCT01048944,NCT01892813,NCT01654107,NCT04709471,NCT04969198,NCT01018394,NCT03482583,NCT00108537,NCT02501265,NCT04262817,NCT01351766,NCT01292642,NCT00755716,NCT00018187,NCT02721082,NCT00586482,NCT00326781,NCT05024747,NCT00064844,NCT02081144,NCT03809897,NCT01050569,NCT01136642,NCT01047527,NCT01478230,NCT00218296,NCT00879918,NCT03168191,NCT05487807,NCT00777569,NCT05060965,NCT01065506,NCT03176784,NCT01980550,NCT04063267,NCT01457469,NCT00086411,NCT02906644,NCT01989507,NCT03972137,NCT00258479,NCT03541044,NCT02271919,NCT03521141,NCT02162849,NCT00969137,NCT01664741,NCT00000447,NCT02511704,NCT04974580,NCT04740008,NCT03611881,NCT05206435,NCT02487953,NCT03879889,NCT01199380,NCT01429129,NCT00657020,NCT02840435,NCT03421210,NCT02179034,NCT00307203,NCT03634839,NCT04535362,NCT00004551,NCT04696380,NCT03442413,NCT01560507,NCT04084210,NCT04590404,NCT01926626,NCT00218283,NCT03860077,NCT02681510,NCT04606797,NCT03163303,NCT01184664,NCT02355665,NCT01806779,NCT01702519,NCT00132236,NCT02587312,NCT01091363,NCT00061074,NCT02896400,NCT00332644,NCT01372254,NCT00364156,NCT01406223,NCT01484717,NCT05253573,NCT00831155,NCT00000444,NCT03492463,NCT01867411,NCT00105482,NCT01056926,NCT00734617,NCT04033237,NCT00507975,NCT02245308,NCT03538938,NCT00775944,NCT00046813,NCT00939029,NCT02964182,NCT05351606,NCT02927847,NCT03635333,NCT05335915,NCT00710034,NCT03069482,NCT02371850,NCT01444131,NCT00888459,NCT00664755,NCT01321931,NCT01058876,NCT03262233,NCT04999644,NCT01592695,NCT01104896,NCT01034020,NCT00018161,NCT03543137,NCT01932996,NCT00985985,NCT00296647,NCT01907594,NCT04490057,NCT04020718,NCT02019459,NCT01208935,NCT01495819,NCT02250534,NCT01296698,NCT00469079,NCT04994444,NCT04521647,NCT04126135,NCT01329614,NCT01438944,NCT05224050,NCT03580525,NCT03243630,NCT00018148,NCT00749463,NCT00960778,NCT01303861,NCT01417429,NCT04946825,NCT05176418,NCT05154669,NCT03612960,NCT02482233,NCT00067158 |
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT05268419,NCT01101412,NCT03838575,NCT01472965,NCT02577718,NCT03253887,NCT02227329,NCT00290290,NCT03083184,NCT03640507,NCT00680459,NCT03757143
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
TDP1,FABP5,HSD17B10,SMN1,TSHR,FABP4,CHRNA3,BLM,ADRA2A,OR51E2,CBR1
|
Hypertensive crisisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA03 |
CHRNA4
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
ADRA2A
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
HIF1A
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
HIF1A
|
Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
CHRNA2
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
CHRNA4
|
Digestive system diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DE2Z |
CHRNA4
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
CHRNA4
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CHRNA2
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CYP2C9
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
TSHR
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
HIF1A
|
Aneurysm/dissectionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD50 |
CHRNA4
|
EnuresisDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C00 |
NCT00240812
|
Congenital melanocytic naevus, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH5YN0 |
NCT04999631
|
ConstipationDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05.0 |
NCT02411175
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
NCT00223691
|
Cyst of pancreasDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC30.0 |
NCT01475331
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
NCT03808818
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT00563342
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
NCT00037141
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT00784433
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
NCT00295984
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
NCT01586962
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
NCT00543881
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT00032084
|
Ventricular tachycardiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71.0 |
NCT01898221
|
NeutropeniaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B00 |
NCT02414581
|
Other specified neuromusculoskeletal and movement-related functionsDisease Category: V.Supplementary section for functioning assessmentDisease ICD-11 Code: VV6Y |
NCT00001925
|
Multiple system atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87.0 |
NCT02149901
|
PulpitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA09.0 |
NCT04669392
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT00553709
|
Alcohol-related neurological disordersDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D44 |
NCT02771587
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
NCT01160848
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
NCT01517022
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
NCT01451060
|
Age-associated cognitive declineDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.0 |
NCT00091468
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NCT03131843
|
Other allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08.03 |
NCT02182518
|
Nontoxic single thyroid noduleDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A01.1 |
NCT03257930
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT02893345
|
HyperhidrosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EE00 |
NCT03416348
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
NCT05470972
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
NCT01172561
|
Blood-forming organ diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3C0Z |
NCT02622126
|
AlopeciaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED70 |
NCT00801086
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT04433767
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT01898221
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT02018263
|
DysmenorrhoeaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34.3 |
NCT02467543
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Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT01205074
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Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT02622126
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CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
NCT01177852
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Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
NCT00247585
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BacteraemiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MA15.0 |
NCT01186172
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Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
NCT02419235
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Neuroblastoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH85Z0 |
NCT00471679
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Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
TSHR
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PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
FABP5
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
CHRNA4
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
FABP4
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
FABP4
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
ADRA2A
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4
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Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
CHRNA7
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Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ADRA2A
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
FABP4
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
GABBR2
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Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CHRNA3
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Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
OR51E2
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM
|