Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC127624 | CD38 | 1 | 17000 | IC50 |
PMID: 21641214 |
| NPC133671 | P4HB | 1 | 19020 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | ALDH1A1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GLA | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178383 | TOP2A | 1 | 38600 | IC50 |
PMID: 11754608 |
| NPC190454 | CD38 | 1 | 16300 | IC50 |
PMID: 21641214 |
| NPC206264 | KDM4E | 1 | 43351.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC217052 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226453 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226453 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC264317 | POLB | 2 |
Median: 44925 Range: 43600 to 46250 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC264317 | GLI1 | 2 |
Median: 32000 Range: 32000 to 32000 |
IC50 |
PMID: 18842418 PMID: 19309080 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46274 | CD38 | 1 | 21800 | IC50 |
PMID: 21641214 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC86412 | L3MBTL1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC86412 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC86655 | CD38 | 1 | 20900 | IC50 |
PMID: 21641214 |
| NPC93730 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93730 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC93730 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93730 | LMNA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93730 | AR | 1 | 23500 | IC50 |
PMID: 19592245 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC137949 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC226331 | GLO1 | 1 | 11700 | IC50 |
PMID: 20801663 |
| NPC264317 | AKR1B1 | 1 | 11000 | IC50 |
PMID: 21561086 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
| NPC93730 | TP53 | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |