Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC161571 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | PMP22 | 1 | 42561.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | CYP1A1 | 1 | 34000 | IC50 |
PMID: 27265259 |
| NPC161571 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | ALDH1A1 | 4 |
Median: 37646 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | MAOB | 1 | 29370 | IC50 |
DOI: 10.1039/C3MD00376K |
| NPC161571 | BCR | 1 | 28000 | IC50 |
PMID: 16686543 |
| NPC161571 | CYP19A1 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 22115839 PMID: 22386564 |
| NPC161571 | SIRT1 | 3 |
Median: 46200 Range: 23600 to 87200 |
EC50 |
PMID: 18046409 PMID: 23316803 PMID: 23316803 |
| NPC161571 | KDM4E | 4 |
Median: 28370.85 Range: 22387.2 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | RELA | 1 | 20000 | IC50 |
Patent: Patent: US20130178536 A1 |
| NPC161571 | ODC1 | 1 | 19000 | IC50 |
PMID: 10075742 |
| NPC303422 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | GAA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | MAPK1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | POLB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC306462 | TREH | 1 | 40000 | IC50 |
PMID: 15546715 |
| NPC306462 | FUCA1 | 1 | 26000 | IC50 |
PMID: 7966130 |
| NPC306462 | GBA2 | 4 |
Median: 24900 Range: 20000 to 30000 |
IC50 |
PMID: 19853441 PMID: 19931460 PMID: 20000679 PMID: 21354674 |
| NPC306462 | GLA | 1 | 18000 | Ki |
PMID: 14684301 |