Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC210460 ABCB1 1 32000 IC50 DOI: 10.1039/C4MD00196F
NPC210460 MAPT 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 POLB 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243509 BACE1 2 Median: 61150
Range: 30500 to 91800
IC50 PMID: 19939683
PMID: 22222157
NPC243509 GAA 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC243509 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243509 ABCB1 1 28000 IC50 DOI: 10.1039/C4MD00196F
NPC33320 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC78612 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33320 CYP3A4 4 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC78612 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862