Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC264317 POLB 2 Median: 44925
Range: 43600 to 46250
IC50 PMID: 14640519
PMID: 18343122
NPC264317 GLI1 2 Median: 32000
Range: 32000 to 32000
IC50 PMID: 18842418
PMID: 19309080
NPC306397 SIRT5 1 46600 IC50 PMID: 24900427
NPC306397 SIRT1 7 Median: 73000
Range: 25000 to 149000
IC50 PMID: 19700324
PMID: 23318905
PMID: 24900427
PMID: 25275824
PMID: 25549554
PMID: 26696402
DOI: 10.1039/C1MD00199J
NPC43246 SLC28A2 1 32000 IC50 PMID: 23388705
NPC92830 CA1 1 36400 Ki PMID: 22892213
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264317 AKR1B1 1 11000 IC50 PMID: 21561086