Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC131624 | PTGS2 | 3 |
Median: 46000 Range: 46000 to 46000 |
IC50 |
PMID: 16038536 PMID: 24631898 PMID: 25956953 |
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC237435 | CDK1 | 1 | 14360 | IC50 |
PMID: 18639462 |
| NPC239312 | THRB | 2 |
Median: 44668.4 Range: 44668.4 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | ABCB1 | 1 | 41000 | IC50 |
PMID: 15481991 |
| NPC239312 | PREP | 1 | 36000 | IC50 |
PMID: 18650094 |
| NPC239312 | SI | 2 |
Median: 43500 Range: 35000 to 52000 |
IC50 |
PMID: 9834167 PMID: 18255289 |
| NPC239312 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | GPR35 | 1 | 28200 | IC50 |
PMID: 24900447 |
| NPC239312 | L3MBTL1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC43211 | SLCO2B1 | 1 | 25900 | Ki |
PMID: 22822035 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC78540 | CALM1;CALM2;CALM3 | 1 | 33430 | IC50 |
PMID: 21129983 |
| NPC78540 | MAPK1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC78540 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC78540 | PTGS2 | 1 | 25500 | IC50 |
PMID: 24332492 |
| NPC78540 | TP53 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC192638 | TOP2A | 1 | 10400 | IC50 |
PMID: 11754608 |
| NPC237435 | PREP | 2 |
Median: 12150 Range: 12000 to 12300 |
IC50 |
PMID: 18650094 PMID: 20058865 |
| NPC239312 | CREB1 | 1 | 13500 | AC50 |
PMID: 18722769 |
| NPC239312 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | ALDH1A1 | 2 |
Median: 13104.55 Range: 11220.2 to 14988.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | GLO1 | 1 | 11000 | IC50 |
PMID: 18258440 |
| NPC239312 | PTPRS | 1 | 10300 | IC50 |
PMID: 26602279 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC78540 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |