Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110126 CYP2C19 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110126 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 TSHR 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 ALDH1A1 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC14958 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC17810 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC17810 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC213552 HTR7 1 47600 IC50 PMID: 16643021
NPC213552 CA4 1 44000 Ki PMID: 26498394
NPC294902 HPGD 3 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 APP 1 32800 IC50 PMID: 22921742
NPC294902 AKR1B1 1 32000 IC50 PMID: 22236472
NPC294902 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 POLB 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC300326 PTGS1 1 39200 IC50 PMID: 22386242
NPC300326 PTGS2 1 28000 IC50 PMID: 22386242
NPC326592 GAA 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC326592 POLB 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC94167 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94167 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94167 CASP7 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94167 CASP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94167 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94167 CYP3A4 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC94167 HSD17B10 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC213552 MET 1 12900 IC50 PMID: 27258622
NPC294902 THRB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 CA4 1 10100 Ki PMID: 20185318
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318
NPC81010 HCAR2 1 14000 Ki PMID: 21167710
NPC94167 HPGD 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862