Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC13826 POLB 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 RAD52 1 15210 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC16107 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC184026 DRD1 1 21270 IC50 PMID: 23332346
NPC184026 DRD2 1 18730 IC50 PMID: 23332346
NPC193949 APAF1 1 16300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC193949 L3MBTL1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202605 CYP3A4 1 30600 IC50 PMID: 17994701
NPC202768 POLB 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202768 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202768 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202768 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202768 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC224651 EGLN1 2 Median: 119500
Range: 19000 to 220000
IC50 PMID: 18942826
PMID: 23234607
NPC24019 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 CASP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 KDM4E 2 Median: 19118.05
Range: 15848.9 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC249797 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC249797 CASP1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC308267 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC308267 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC325871 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC325871 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC325871 HSD17B10 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC325871 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51957 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 TERT 1 37000 IC50 PMID: 22336246
NPC67978 KMT2A 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC77572 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 BLM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 THRB 2 Median: 42239.55
Range: 39810.7 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC78222 KDM4E 1 34435.5 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 CASP7 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 CASP1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC16452 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC16452 CYP2D6 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC202768 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202768 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 CYP2C9 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 KDM4E 2 Median: 24035.3
Range: 12589.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC24019 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 POLB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC249797 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC249797 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC308267 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51957 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78222 TP53 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862