Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC119133 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC167400 | ALDH1A1 | 1 | 18029.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178383 | TOP2A | 1 | 38600 | IC50 |
PMID: 11754608 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC18205 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203891 | XDH | 1 | 36500 | IC50 |
PMID: 10425142 |
| NPC203891 | PKM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC203891 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | PTGS1 | 2 |
Median: 58350 Range: 36700 to 80000 |
IC50 |
PMID: 11858749 PMID: 16038536 |
| NPC219876 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | BLM | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | MAPT | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | APEX1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC240431 | EPHX2 | 1 | 17230 | IC50 |
PMID: 24679441 |
| NPC250436 | CREBBP | 1 | 50000 | IC50 |
PMID: 26701186 |
| NPC250436 | EP300 | 1 | 30000 | IC50 |
PMID: 26701186 |
| NPC250436 | MMP7 | 1 | 21500 | IC50 |
PMID: 19524436 |
| NPC250436 | PIN1 | 1 | 20000 | IC50 |
PMID: 23796453 |
| NPC252603 | ADORA1 | 1 | 17104 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC256849 | ADORA1 | 5 |
Median: 44900 Range: 44000 to 44900 |
Ki |
PMID: 21664729 PMID: 23602401 PMID: 24139167 PMID: 24139167 PMID: 24164628 |
| NPC256849 | ADORA2A | 1 | 20472 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC264317 | POLB | 2 |
Median: 44925 Range: 43600 to 46250 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC264317 | GLI1 | 2 |
Median: 32000 Range: 32000 to 32000 |
IC50 |
PMID: 18842418 PMID: 19309080 |
| NPC38779 | ACHE | 1 | 28000 | IC50 |
PMID: 20053484 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC53889 | MMP14 | 1 | 15600 | IC50 |
PMID: 17850214 |
| NPC82295 | CA2 | 1 | 32500 | Ki |
PMID: 22245047 |
| NPC82295 | CA1 | 1 | 27400 | Ki |
PMID: 22245047 |
| NPC126029 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | KDM4E | 2 |
Median: 16803.7 Range: 11220.2 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC219876 | KDM4E | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | POLB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225585 | PTPN1 | 1 | 12800 | IC50 |
PMID: 18798681 |
| NPC250436 | ELANE | 1 | 12800 | IC50 |
PMID: 20004577 |
| NPC252603 | ADORA2A | 1 | 12007 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC256849 | ADORA3 | 3 |
Median: 13300 Range: 13300 to 13300 |
Ki |
PMID: 12139454 PMID: 24139167 PMID: 24139167 |
| NPC256849 | ADORA2B | 10 |
Median: 27150 Range: 10400 to 33800 |
Ki |
PMID: 12014951 PMID: 19569717 PMID: 19569717 PMID: 20188574 PMID: 20537438 PMID: 21664729 PMID: 24139167 PMID: 24139167 PMID: 24164628 PMID: 26824742 |
| NPC256849 | GDA | 1 | 10200 | Ki |
PMID: 20716488 |
| NPC264317 | AKR1B1 | 1 | 11000 | IC50 |
PMID: 21561086 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |