Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC109083 | KMT2A | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | CYP1A2 | 1 | 40000 | IC50 |
PMID: 18249473 |
| NPC109083 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | HBB | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | CYP2B6 | 1 | 24500 | IC50 |
PMID: 18249473 |
| NPC109083 | HPGD | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | VDR | 1 | 20000 | EC50 |
PMID: 23276449 |
| NPC109083 | ALDH1A1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | KDM4E | 2 |
Median: 24068.2 Range: 19952.6 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | STAT3 | 2 |
Median: 19250 Range: 19250 to 19250 |
IC50 |
PMID: 23376248 PMID: 23434226 |
| NPC109083 | CYP3A4 | 1 | 16300 | IC50 |
PMID: 18249473 |
| NPC109083 | TP53 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | TLR9 | 1 | 15266 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | TOP2A | 1 | 15000 | IC50 |
DOI: 10.1007/s00044-011-9587-3 |
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC124289 | PTPN1 | 1 | 35100 | IC50 |
PMID: 23387824 |
| NPC124289 | PTPN2 | 1 | 15700 | IC50 |
PMID: 23387824 |
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13991 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC160900 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | TP53 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | HBB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | KDM4E | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | PKM | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | CREBBP | 1 | 25000 | IC50 |
PMID: 26701186 |
| NPC160900 | MAOB | 1 | 21500 | Ki |
PMID: 26819666 |
| NPC160900 | ALOX12 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | GSK3B | 1 | 17950 | IC50 |
PMID: 26696252 |
| NPC160900 | CASP1 | 2 |
Median: 23735.85 Range: 15848.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | KMT2A | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | HPGD | 2 |
Median: 26968.05 Range: 14125.4 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC163984 | ALDH1A1 | 2 |
Median: 25285.5 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC171736 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC171736 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC171736 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC217226 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
| NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
| NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
| NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC285716 | STAT3 | 1 | 14210 | IC50 |
PMID: 26788588 |
| NPC287331 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | CYP19A1 | 1 | 44200 | IC50 |
PMID: 16643058 |
| NPC294548 | BLM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | F3 | 1 | 30000 | IC50 |
PMID: 9834151 |
| NPC294548 | HPGD | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | MAPT | 3 |
Median: 28183.8 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | LMNA | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PLA2G1B | 1 | 22300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | KDM4E | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PPARD | 1 | 16000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC294548 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | ATG4B | 1 | 15300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300940 | PTPN1 | 1 | 45600 | IC50 |
PMID: 23387824 |
| NPC300940 | PTPN2 | 1 | 26800 | IC50 |
PMID: 23387824 |
| NPC66677 | PTPN2 | 1 | 45900 | IC50 |
PMID: 23387824 |
| NPC66677 | PTPN1 | 1 | 35700 | IC50 |
PMID: 23387824 |
| NPC68269 | CAMK2A | 1 | 37000 | IC50 |
PMID: 22989913 |
| NPC68269 | PTGS2 | 1 | 36370 | IC50 |
PMID: 15780608 |
| NPC68269 | GLO1 | 2 |
Median: 18100 Range: 18000 to 18200 |
Ki |
PMID: 21237663 PMID: 21689932 |
| NPC68889 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC7491 | CYP2C9 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC83987 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99886 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99886 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC109083 | CAMK2A | 5 |
Median: 33000 Range: 13000 to 45000 |
IC50 |
PMID: 22989913 PMID: 22989913 PMID: 22989913 PMID: 22989913 PMID: 22989913 |
| NPC109083 | CA14 | 1 | 11730 | Ki |
PMID: 20674354 |
| NPC109083 | CA3 | 1 | 11300 | Ki |
PMID: 20674354 |
| NPC109083 | PRKCQ | 1 | 11080 | EC50 |
PMID: 20100661 |
| NPC109083 | PTGS2 | 2 |
Median: 45130 Range: 11060 to 79200 |
IC50 |
PMID: 15780608 PMID: 21345672 |
| NPC109083 | PRKCD | 1 | 10670 | EC50 |
PMID: 20100661 |
| NPC109083 | MMP13 | 1 | 10300 | IC50 |
PMID: 18358729 |
| NPC109083 | CA5A | 1 | 10250 | Ki |
PMID: 20674354 |
| NPC160900 | CASP7 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | ALOX15 | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC160900 | CYP3A4 | 4 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC259134 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC7491 | CYP2C19 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |