Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC168829 POLB 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC168829 GAA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC168829 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC189470 PTPRCAP 1 17000 IC50 DOI: 10.1016/0960-894X(95)00250-W
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC288411 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288411 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 HPGD 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 MAPT 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC43246 SLC28A2 1 32000 IC50 PMID: 23388705
NPC49074 PTGS1 1 36000 IC50 PMID: 16038536
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288411 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862