Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC103540 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103540 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103540 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103540 | TDP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103540 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103540 | ALOX15 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC199357 | EPHX2 | 1 | 24300 | IC50 |
PMID: 26483136 |
| NPC199463 | EPHX2 | 1 | 26300 | IC50 |
PMID: 26483136 |
| NPC213052 | EPHX2 | 1 | 37500 | IC50 |
PMID: 26483136 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC245531 | ALDH1A1 | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | EPHX2 | 1 | 36400 | IC50 |
PMID: 26483136 |
| NPC254847 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | TP53 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | PTP4A3 | 2 |
Median: 31500 Range: 28000 to 35000 |
IC50 |
PMID: 22137788 PMID: 22137788 |
| NPC254847 | NPC1 | 1 | 20596.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | ALOX12 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | USP2 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | KDM4E | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | BRCA1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ELANE | 1 | 18000 | IC50 |
PMID: 1578486 |
| NPC282923 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | PLEC | 2 |
Median: 93960.05 Range: 32104.8 to 155815.3 |
IC50 |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALDH1A1 | 2 |
Median: 33997.25 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | THRB | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | CASP7 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | PTPN7 | 1 | 19620 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | BCHE | 1 | 17000 | IC50 |
PMID: 24568372 |
| NPC288089 | CASP1 | 5 |
Median: 25118.9 Range: 15848.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC3224 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC37543 | EPHX2 | 1 | 26400 | IC50 |
PMID: 26483136 |
| NPC46958 | EPHX2 | 1 | 40600 | IC50 |
PMID: 26483136 |
| NPC70622 | EPHX2 | 1 | 26800 | IC50 |
PMID: 26372074 |
| NPC103540 | HTT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | TDP1 | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | CYP2D6 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | ALDH1A1 | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | MAPK1 | 2 |
Median: 11904.75 Range: 11220.2 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | TDP1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278175 | TP53 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | KDM4E | 2 |
Median: 21154.6 Range: 14125.4 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | LMNA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC288089 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |