Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC100980 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC167400 | ALDH1A1 | 1 | 18029.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178383 | TOP2A | 1 | 38600 | IC50 |
PMID: 11754608 |
| NPC187770 | TYR | 1 | 32500 | IC50 |
PMID: 25726329 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC231772 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TP53 | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | GALK1 | 1 | 47269 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2C9 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | GAA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | DAPK1 | 1 | 21000 | IC50 |
PMID: 26322379 |
| NPC279121 | CDK2 | 1 | 20000 | IC50 |
PMID: 17178224 |
| NPC279121 | TDP1 | 2 |
Median: 29881.65 Range: 19952.6 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | ABCB1 | 1 | 19600 | IC50 |
PMID: 15240100 |
| NPC279121 | GPR35 | 1 | 18600 | IC50 |
PMID: 24900447 |
| NPC279121 | AMY1A;AMY1B;AMY1C | 1 | 18400 | IC50 |
PMID: 18507367 |
| NPC279121 | MMP3 | 1 | 16200 | IC50 |
PMID: 22658537 |
| NPC279121 | CYP2C19 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | BLM | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC287895 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287895 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC8466 | TRPA1 | 1 | 16000 | EC50 |
PMID: 20356305 |
| NPC8466 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC9743 | HIF1A | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC9743 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100980 | CA14 | 4 |
Median: 11500 Range: 11500 to 11500 |
Ki |
PMID: 20185318 PMID: 20590092 PMID: 20674354 PMID: 23010455 |
| NPC100980 | CA1 | 9 |
Median: 10200 Range: 10200 to 10200 |
Ki |
PMID: 20185318 PMID: 20590092 PMID: 20674354 PMID: 21282059 PMID: 23010455 PMID: 23265898 PMID: 24189056 PMID: 26073005 PMID: 26520662 |
| NPC231772 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | SMN1;SMN2 | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | USP2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MAPT | 3 |
Median: 12589.3 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | SYK | 1 | 12000 | IC50 |
PMID: 22257213 |
| NPC279121 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MMP13 | 1 | 10050 | IC50 |
PMID: 22658537 |
| NPC9743 | ALOX12 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC9743 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |