Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC120066 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 CTSD 1 42300 IC50 DOI: 10.1007/s00044-012-0397-z
NPC136330 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 HPGD 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 ABCB1 2 Median: 44800
Range: 15500 to 74100
IC50 PMID: 12130727
PMID: 12130727
NPC136330 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 POLB 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 RAD52 1 15210 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC167096 TRPV1 1 19952.62 EC50 PMID: 20381363
NPC214036 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 MAPK1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC255817 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC49075 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC49075 PDE1A 1 22000 IC50 PMID: 1955879
NPC49075 CYP3A4 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 TERT 1 37000 IC50 PMID: 22336246
NPC120066 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC136330 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC13826 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13826 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC255817 SMN1;SMN2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC255817 HSD17B10 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC255817 CYP2D6 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC255817 ALDH1A1 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862