Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC107482 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC119949 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC119949 SMN1;SMN2 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC143168 CYP2C19 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC143168 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC143168 ALDH1A1 2 Median: 21854.2
Range: 19952.6 to 23755.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC163556 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC163556 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC279026 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC279026 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC279026 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC279026 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC292792 PPARA 1 46500 EC50 PMID: 22381047
NPC292792 PPARG 1 40000 EC50 PMID: 22381047
NPC292792 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68889 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP19A1 1 48000 IC50 PMID: 16643058
NPC85813 F3 1 41000 IC50 PMID: 9834151
NPC85813 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC143168 HPGD 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC143168 TP53 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 FABP4 2 Median: 15650
Range: 13600 to 17700
IC50 PMID: 20471252
PMID: 25461324
NPC85813 PTGS1 1 13000 IC50 PMID: 16038536