Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC119949 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC119949 | SMN1;SMN2 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC123526 | PPARD | 1 | 33900 | EC50 |
PMID: 22381047 |
| NPC123526 | PPARG | 1 | 18900 | EC50 |
PMID: 22381047 |
| NPC127326 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC129687 | CYP2D6 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC135961 | PPARD | 1 | 22600 | EC50 |
PMID: 26916438 |
| NPC135961 | PPARG | 1 | 19300 | EC50 |
PMID: 17060520 |
| NPC135961 | PPARA | 1 | 15700 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13991 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161557 | PPARD | 1 | 49500 | EC50 |
PMID: 22381047 |
| NPC163984 | ALDH1A1 | 2 |
Median: 25285.5 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC186098 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC186098 | HPGD | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | CYP2D6 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | KMT2A | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | ABCB11 | 1 | 30700 | IC50 |
PMID: 21965623 |
| NPC190945 | MAPK1 | 2 |
Median: 32464.8 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | GSR | 1 | 23400 | IC50 |
PMID: 21795044 |
| NPC190945 | TDP1 | 5 |
Median: 44668.4 Range: 22387.2 to 56234.1 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | ALOX12 | 2 |
Median: 27005 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | ADORA2A | 2 |
Median: 22200 Range: 22200 to 22200 |
Ki |
PMID: 9258366 PMID: 9258366 |
| NPC190945 | TBXAS1 | 1 | 18594 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC190945 | HTR2C | 1 | 18273 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC190945 | MTOR | 1 | 16481.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC193666 | PPARG | 1 | 48700 | EC50 |
PMID: 22381047 |
| NPC240684 | CDK2 | 1 | 25000 | IC50 |
PMID: 20097066 |
| NPC247871 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC255566 | PPARD | 1 | 47600 | EC50 |
PMID: 22381047 |
| NPC255566 | PPARG | 1 | 22600 | EC50 |
PMID: 22381047 |
| NPC257124 | AR | 2 |
Median: 19027.305 Range: 19000 to 19054.61 |
IC50 |
PMID: 20226658 PMID: 20226658 |
| NPC287331 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC291066 | ALOX12 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC291066 | CYP2A6 | 2 |
Median: 25001.725 Range: 25000 to 25003.45 |
IC50 |
PMID: 15658857 PMID: 19110342 |
| NPC292792 | PPARA | 1 | 46500 | EC50 |
PMID: 22381047 |
| NPC292792 | PPARG | 1 | 40000 | EC50 |
PMID: 22381047 |
| NPC292792 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC307123 | ADRB2 | 1 | 14634 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC32441 | GSK3B | 1 | 45700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC32441 | AKR1B1 | 1 | 28870 | IC50 |
PMID: 22261024 |
| NPC32441 | CYP1A2 | 1 | 26339 | IC50 |
PMID: 20696580 |
| NPC32441 | CALM1;CALM2;CALM3 | 1 | 22010 | IC50 |
PMID: 21129983 |
| NPC32441 | CBR1 | 1 | 21480 | IC50 |
PMID: 19097799 |
| NPC32441 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC32441 | CYP1A1 | 1 | 15167 | IC50 |
PMID: 20696580 |
| NPC32441 | HSD17B2 | 1 | 14400 | IC50 |
PMID: 18533708 |
| NPC54542 | PPARA | 1 | 46100 | EC50 |
PMID: 22381047 |
| NPC56271 | MAPT | 3 |
Median: 35481.3 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC56271 | BACE1 | 1 | 20000 | IC50 |
PMID: 27046190 |
| NPC56271 | KDR | 2 |
Median: 14800 Range: 14800 to 14800 |
IC50 |
PMID: 21353546 DOI: 10.1039/C0MD00183J |
| NPC68889 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC69213 | CDK2 | 1 | 15000 | IC50 |
PMID: 20097066 |
| NPC71853 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX15 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC82337 | PPARD | 1 | 48500 | EC50 |
PMID: 8759172 |
| NPC82337 | PPARG | 1 | 21700 | EC50 |
PMID: 24369840 |
| NPC82337 | PPARA | 1 | 19500 | EC50 |
PMID: 1965200 |
| NPC85661 | ALDH1A1 | 2 |
Median: 42239.55 Range: 39810.7 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC97870 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC97870 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC97870 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC130398 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | KDM4E | 5 |
Median: 22387.2 Range: 14125.4 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | HPGD | 3 |
Median: 15848.9 Range: 11220.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC190945 | NFKB1 | 2 |
Median: 11220.2 Range: 11220.2 to 11220.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | PTGS1 | 1 | 11000 | IC50 |
PMID: 16038536 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC32441 | ESR2 | 1 | 13473 | IC50 |
PMID: 17149865 |
| NPC32441 | CYP2C9 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX12 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85661 | MAPT | 3 |
Median: 14125.4 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |