Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100551 CA14 1 49800 Ki PMID: 18579385
NPC100551 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC107482 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 BACE1 1 33000 IC50 DOI: 10.1007/s00044-012-0353-y
NPC19174 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 MTOR 1 26121.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 APP 1 19700 IC50 PMID: 23786711
NPC19174 GMNN 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 PMP22 1 15101.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 CA6 2 Median: 1165950
Range: 11900 to 2320000
Ki PMID: 18579385
PMID: 21669522
NPC100551 CA4 1 11100 Ki PMID: 18579385
NPC19174 CHRNA7 1 11600 EC50 PMID: 25232969