Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC138113 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC154176 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC18205 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC195788 SLCO1B1 1 46800 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC195788 SLCO1B3 1 43500 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC195788 ABCC1 1 30000 IC50 PMID: 17132069
NPC195788 CYP3A4 1 26000 IC50 PMID: 18980381
NPC195788 ABCC2 1 21000 IC50 PMID: 18321710
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC260909 SLCO1B1 1 44000 IC50 PMID: 22541068
NPC314333 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC315634 TDP1 2 Median: 49489.2
Range: 28183.8 to 70794.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC315634 KDM4E 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC315634 MAPT 2 Median: 22016.35
Range: 15848.9 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC79056 POLB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC79056 CTDSP1 1 20733 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC88445 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC88445 LMNA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260909 SLCO1B3 2 Median: 23890
Range: 11000 to 36780
IC50 PMID: 22541068
PMID: 25618019
NPC294909 HBB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294909 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294909 CYP2C19 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862