Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC115207 | PTPN1 | 1 | 18690 | IC50 |
PMID: 24224843 |
| NPC124302 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC124302 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC131624 | PTGS2 | 3 |
Median: 46000 Range: 46000 to 46000 |
IC50 |
PMID: 16038536 PMID: 24631898 PMID: 25956953 |
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | RAD52 | 1 | 15210 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC16107 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161557 | PPARD | 1 | 49500 | EC50 |
PMID: 22381047 |
| NPC202605 | CYP3A4 | 1 | 30600 | IC50 |
PMID: 17994701 |
| NPC202768 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | HPGD | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC257124 | AR | 2 |
Median: 19027.305 Range: 19000 to 19054.61 |
IC50 |
PMID: 20226658 PMID: 20226658 |
| NPC257582 | CYP3A4 | 1 | 25600 | IC50 |
PMID: 21138310 |
| NPC296482 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296482 | BCHE | 1 | 18970 | IC50 |
PMID: 21924611 |
| NPC296482 | MAPT | 2 |
Median: 21450.85 Range: 17782.8 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC305016 | CYP3A4 | 1 | 23200 | Ki |
PMID: 16248836 |
| NPC36229 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC36229 | MAPT | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | ALDH1A1 | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | TERT | 1 | 37000 | IC50 |
PMID: 22336246 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73020 | CYP2D6 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73020 | CYP2C9 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77572 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC87125 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC87125 | TDP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC87125 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC87125 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115207 | ALOX5 | 1 | 13800 | IC50 |
PMID: 17378609 |
| NPC13826 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | NPSR1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | PTGS1 | 1 | 11000 | IC50 |
PMID: 16038536 |
| NPC296482 | CYP3A4 | 4 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | TSHR | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | MAPT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC87125 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99572 | CYP3A4 | 1 | 13700 | IC50 |
PMID: 15679319 |