Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC10251 | L3MBTL1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116709 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | BCHE | 1 | 43100 | Ki |
PMID: 19879672 |
| NPC116775 | ALDH1A1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | CDK6 | 2 |
Median: 22000 Range: 22000 to 22000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC116775 | GLO1 | 1 | 20600 | IC50 |
PMID: 18258440 |
| NPC116775 | KDM4E | 2 |
Median: 27829.8 Range: 15848.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | HSD17B10 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | BACE1 | 1 | 14700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC132307 | LMNA | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC133671 | P4HB | 1 | 19020 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137958 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137958 | SLC1A3 | 1 | 35000 | Ki |
PMID: 18578477 |
| NPC156461 | GAPDH | 7 |
Median: 35000000 Range: 35000 to 100000000 |
IC50 |
PMID: 7562915 PMID: 7562915 PMID: 7562915 PMID: 7932587 PMID: 7932587 PMID: 7932587 PMID: 9822549 |
| NPC156461 | ADORA2B | 3 |
Median: 24000 Range: 24000 to 24000 |
EC50 |
PMID: 20541935 PMID: 21388809 PMID: 24164628 |
| NPC156461 | SLC29A1 | 1 | 17000 | IC50 |
PMID: 23388705 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
| NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
| NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC193471 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
| NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
| NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
| NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
| NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
| NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
| NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
| NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
| NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
| NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
| NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
| NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
| NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
| NPC208793 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC208793 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC208793 | CYP2C19 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC224651 | EGLN1 | 2 |
Median: 119500 Range: 19000 to 220000 |
IC50 |
PMID: 18942826 PMID: 23234607 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC262962 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC262962 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273330 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273330 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPT | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | EPHX2 | 1 | 21760 | IC50 |
PMID: 24679441 |
| NPC282895 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282895 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300326 | PTGS1 | 1 | 39200 | IC50 |
PMID: 22386242 |
| NPC300326 | PTGS2 | 1 | 28000 | IC50 |
PMID: 22386242 |
| NPC43246 | SLC28A2 | 1 | 32000 | IC50 |
PMID: 23388705 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC95381 | TTR | 1 | 23000 | EC50 |
PMID: 25314129 |
| NPC10251 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | MAPT | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC156461 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18335 | XDH | 1 | 10890 | IC50 |
PMID: 17379526 |
| NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
| NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
| NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
| NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
| NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
| NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
| NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
| NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
| NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
| NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC293378 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |